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The map label for this gene is kdgR [H]

Identifier: 126447375

GI number: 126447375

Start: 1709503

End: 1710243

Strand: Direct

Name: kdgR [H]

Synonym: BMA10247_A1774

Alternate gene names: 126447375

Gene position: 1709503-1710243 (Clockwise)

Preceding gene: 126446691

Following gene: 126447723

Centisome position: 72.66

GC content: 67.75

Gene sequence:

>741_bases
ATGAGTTATGTCGTCGATGCCGTTGACAATGCGCTGAAGCTGTTGAATTGCGTGGCCGAGCACCCGAACCTCGGCGTGAC
CCGGCTCGCATCGAAGCTCGGCATCAACAAGTCGCGCACGTACCGCATGCTGTGCACGCTCGAACTGCACCACTTCGTGA
CACGGGACGCGCGAACGTCGACTTATGTGCTCGGAACGCAGGCATTCGTGATCGGCGTCGCCGCGGCGCTGCAAAGCGCG
CTCGTGCGAGCCGCCGAGCACCCGATGCTCGCGCTCGGCCAATCCGTCAACGAAACGGTGATGCTGCGGGTTCGCGAAGG
CTTCGATACGGTTTGCGTCGCGCGGCACGCAACGGTGCGCGACGCTCGCATGGCGGGCTCCGTCTGCAACCGGCGGCCGC
TCGGCGTCGGCGCGGCGGGCAAGGTACTACTGGCGTTCGCGCTCGATGCGGTGCGCGACGAATACCTCGCCCGCCGCGAG
AAGACCGCGCCGGGCGGCTCGGCCGCGCTCGCCGACGAACTGGACACGATCGCGCGCAGAGGCTACGCGATCGGCATCGG
CGAAGCGGCGGCGAGCACCGTCGAGATCGCCGTGCCGGTGCGGGACGGGCGCGGCGCGACGATCGCCTCCTTGAGCGTGG
CGGGGCCGAACCTGCGGATGCCCCACGCCGACACGGCGCGCTATCTCGAGAAGTTGCAGGCGTGCAGCCGCGCCATTTCG
GCCGAATTCGAATACATGTAA

Upstream 100 bases:

>100_bases
ATCCGGCGGCAGACAAACACGAATTCGCGTGCGATGAGCACGCTTTCCCCCAATAAAAAAATCCGCGATTTCCAATGTTA
TTCGTACTTCGAGAGTCGAA

Downstream 100 bases:

>100_bases
CGGCGCGCCTCATGATCACCCGGCGCGAACCGCACCCGCCGGGCCGCGCGCCGCGATCGCCTCACGCCGGCCGCCATCGC
GCCGCGGCATCGCGAAGCGA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSYVVDAVDNALKLLNCVAEHPNLGVTRLASKLGINKSRTYRMLCTLELHHFVTRDARTSTYVLGTQAFVIGVAAALQSA
LVRAAEHPMLALGQSVNETVMLRVREGFDTVCVARHATVRDARMAGSVCNRRPLGVGAAGKVLLAFALDAVRDEYLARRE
KTAPGGSAALADELDTIARRGYAIGIGEAAASTVEIAVPVRDGRGATIASLSVAGPNLRMPHADTARYLEKLQACSRAIS
AEFEYM

Sequences:

>Translated_246_residues
MSYVVDAVDNALKLLNCVAEHPNLGVTRLASKLGINKSRTYRMLCTLELHHFVTRDARTSTYVLGTQAFVIGVAAALQSA
LVRAAEHPMLALGQSVNETVMLRVREGFDTVCVARHATVRDARMAGSVCNRRPLGVGAAGKVLLAFALDAVRDEYLARRE
KTAPGGSAALADELDTIARRGYAIGIGEAAASTVEIAVPVRDGRGATIASLSVAGPNLRMPHADTARYLEKLQACSRAIS
AEFEYM
>Mature_245_residues
SYVVDAVDNALKLLNCVAEHPNLGVTRLASKLGINKSRTYRMLCTLELHHFVTRDARTSTYVLGTQAFVIGVAAALQSAL
VRAAEHPMLALGQSVNETVMLRVREGFDTVCVARHATVRDARMAGSVCNRRPLGVGAAGKVLLAFALDAVRDEYLARREK
TAPGGSAALADELDTIARRGYAIGIGEAAASTVEIAVPVRDGRGATIASLSVAGPNLRMPHADTARYLEKLQACSRAISA
EFEYM

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=249, Percent_Identity=30.5220883534137, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786468, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082359, Length=225, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789999, Length=244, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 26267; Mature: 26135

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVVDAVDNALKLLNCVAEHPNLGVTRLASKLGINKSRTYRMLCTLELHHFVTRDARTS
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCC
TYVLGTQAFVIGVAAALQSALVRAAEHPMLALGQSVNETVMLRVREGFDTVCVARHATVR
EEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
DARMAGSVCNRRPLGVGAAGKVLLAFALDAVRDEYLARREKTAPGGSAALADELDTIARR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GYAIGIGEAAASTVEIAVPVRDGRGATIASLSVAGPNLRMPHADTARYLEKLQACSRAIS
CEEEEECCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AEFEYM
CCCCCC
>Mature Secondary Structure 
SYVVDAVDNALKLLNCVAEHPNLGVTRLASKLGINKSRTYRMLCTLELHHFVTRDARTS
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCC
TYVLGTQAFVIGVAAALQSALVRAAEHPMLALGQSVNETVMLRVREGFDTVCVARHATVR
EEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
DARMAGSVCNRRPLGVGAAGKVLLAFALDAVRDEYLARREKTAPGGSAALADELDTIARR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GYAIGIGEAAASTVEIAVPVRDGRGATIASLSVAGPNLRMPHADTARYLEKLQACSRAIS
CEEEEECCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AEFEYM
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]