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The map label for this gene is dacA [H]

Identifier: 126447167

GI number: 126447167

Start: 1206254

End: 1207255

Strand: Direct

Name: dacA [H]

Synonym: BMA10247_A1242

Alternate gene names: 126447167

Gene position: 1206254-1207255 (Clockwise)

Preceding gene: 126447214

Following gene: 126446511

Centisome position: 51.27

GC content: 72.16

Gene sequence:

>1002_bases
ATGACGACCGAGCCTCTTTCGACAACCGTCGCACGCGGCAGCCGCCGCGCGGCATGTGCGCTGCTCCGCACGCCCTCGCG
CCTGTTCGCCGCGCTCTTCGTGTCCGCGGCATGCGCCGCTCCGAACGGCGCGCGAGCCGCGCCGGCCCCGGCACCGGCGA
TCCAGGCCGCGTCCTGGCTCGTCGTCGACGCCGATTCCGGCAAGACGCTCGGCGCGCACAATGTCGACGCGCGCCGCGAG
CCGGCGTCGCTGACCAAGCTGATGACCGCGTACGTCGCGTTCGACGCCCTCGAGCGCGCCGCGCTGCGCTGGGACGACAC
CGTCACGGTGGCCGCCGACGACATCGCCTCCGTCGGCCGCGACGAGGCGCGCATGTATCTGACGCCCGGGCAGCGCGTTC
GCGTGCGCGACCTGATGCGCGGCCTGATCGTCGCCTCCGCGAACGACGCGGCGCTCGTGCTCGCGAAGCGCATCGGCGGC
AGCCCCGCCGGCTTCGCGACGATGATGAACGACACGGCGCGCCGGCTCGGCATGCGCGATTCGCACTTCGTGTCGCCGTC
CGGCATCACGACGCCCAATCACTATTCGACCGCGCACGACCTATCGATTCTCGCGCAGCGTCTGAACCGCGATTTCCCGG
CGTTCTACACGTTCTCGTCGCAACGGCATTTCGCGTACGGCGCGTTCGCGAAGACCAACAAGAATCGTCTGCTCGGCGCC
GATCCGAGCGTCGACGGCATGAAGACCGGCCATACGAACGCAGCCGGATGGTGCATGGTCGTCACCGCGAAGCGGCCCGT
CGGCGGCGCGCGCGCGCGGCACCGCGTGATCGCGGTGCTGCTCGGCGAGCCGACCGAGAAGCAGCGGCTCGCCGACGCCC
GCGCGCTCCTCGATCAGGGCTTCGCGTCGCTCGGCGCCGACGCGCCGGCGGCGAACGCCGTGCAACGGGCGAACGCGCGC
CCCGGCGAGCATCGCGCGCAAGCGCGGGCGCGCATGCTCTGA

Upstream 100 bases:

>100_bases
GCCGGCGATTTGCGCTTCGCCGTTCCAGCCGCTTTCGCGAGCCGCCTTCCCGATCCCGCGTCTTCTGCCGTTTTCCATCC
TCTGCATACCTGATTTCCCC

Downstream 100 bases:

>100_bases
CGCCCGCGCGGCGCCGCGTGCGGGCGCGCCGGCGGCGCGACATGCGCGTGCAGTTGTCGCGTTGTCGTTGTCGTTGTCGT
TGTCGATGTTGTCGTCGTCT

Product: D-alanyl-D-alanine carboxypeptidase family protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTTEPLSTTVARGSRRAACALLRTPSRLFAALFVSAACAAPNGARAAPAPAPAIQAASWLVVDADSGKTLGAHNVDARRE
PASLTKLMTAYVAFDALERAALRWDDTVTVAADDIASVGRDEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGG
SPAGFATMMNDTARRLGMRDSHFVSPSGITTPNHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQGFASLGADAPAANAVQRANAR
PGEHRAQARARML

Sequences:

>Translated_333_residues
MTTEPLSTTVARGSRRAACALLRTPSRLFAALFVSAACAAPNGARAAPAPAPAIQAASWLVVDADSGKTLGAHNVDARRE
PASLTKLMTAYVAFDALERAALRWDDTVTVAADDIASVGRDEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGG
SPAGFATMMNDTARRLGMRDSHFVSPSGITTPNHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQGFASLGADAPAANAVQRANAR
PGEHRAQARARML
>Mature_332_residues
TTEPLSTTVARGSRRAACALLRTPSRLFAALFVSAACAAPNGARAAPAPAPAIQAASWLVVDADSGKTLGAHNVDARREP
ASLTKLMTAYVAFDALERAALRWDDTVTVAADDIASVGRDEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGGS
PAGFATMMNDTARRLGMRDSHFVSPSGITTPNHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGAD
PSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQGFASLGADAPAANAVQRANARP
GEHRAQARARML

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082022, Length=286, Percent_Identity=39.8601398601399, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1787062, Length=277, Percent_Identity=36.4620938628159, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1786851, Length=273, Percent_Identity=35.5311355311355, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI87082054, Length=226, Percent_Identity=30.9734513274336, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 35397; Mature: 35265

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEPLSTTVARGSRRAACALLRTPSRLFAALFVSAACAAPNGARAAPAPAPAIQAASWL
CCCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCEEE
VVDADSGKTLGAHNVDARREPASLTKLMTAYVAFDALERAALRWDDTVTVAADDIASVGR
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
DEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGGSPAGFATMMNDTARRLGMRD
CCCEEEECCCCEEHHHHHHHHHEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
SHFVSPSGITTPNHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
CCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHEECCCCCEECC
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQG
CCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
FASLGADAPAANAVQRANARPGEHRAQARARML
HHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TTEPLSTTVARGSRRAACALLRTPSRLFAALFVSAACAAPNGARAAPAPAPAIQAASWL
CCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCEEE
VVDADSGKTLGAHNVDARREPASLTKLMTAYVAFDALERAALRWDDTVTVAADDIASVGR
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
DEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGGSPAGFATMMNDTARRLGMRD
CCCEEEECCCCEEHHHHHHHHHEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
SHFVSPSGITTPNHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
CCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHEECCCCCEECC
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQG
CCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
FASLGADAPAANAVQRANARPGEHRAQARARML
HHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]