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The map label for this gene is ttuB [H]

Identifier: 126447030

GI number: 126447030

Start: 1790302

End: 1791624

Strand: Direct

Name: ttuB [H]

Synonym: BMA10247_A1860

Alternate gene names: 126447030

Gene position: 1790302-1791624 (Clockwise)

Preceding gene: 126446351

Following gene: 126445997

Centisome position: 76.1

GC content: 65.08

Gene sequence:

>1323_bases
ATGATTCCCAGCCAAGCAGCCGCGGCCCGGCCGCTCGAGGCGGCCGGACAGGCCGAGCTCGATCTGACCTACCGGAAAGT
GTTCTGGCGCATCGTGCCGTTCCTGATGCTCTGCTACGTGGTGGCGTACCTGGACCGCGTGAACGTCGGCTTCGCGAAGC
TGCAGATGTCGCAGGATCTCGCGTTCAGCGAAACCGTGTTCGGCCTCGGCGCGGGCATCTTCTTTCTCGGCTACTTCCTG
TTCGAGTTGCCGAGCAACATGCTGATGCACCGCATCGGCGCGCGCATCTGGATCGCGCGGATCATGATCACGTGGGGCCT
GCTGTCCGCGCTGTTCGCGTTCGTGAAGACGCCCACGCAGTTCTACGTGCTGCGCTTCCTGCTGGGCCTCGCGGAGGCGG
GCTTCTACCCGGGCGTGATCCTGTATCTCACTTACTGGTTCCCGACGCACCGCCGCGCGAAGATCATCGCGGTGTTCATG
TCGGCGATTCCGGTGTCGGGCATCTTCGGCAATCCGCTGTCCGGCTGGATCATGGAGCGCTTCCACGGCGGCTCGGGCTT
TCACGGCTGGCAATGGATGTTCGTGATCGAGGCGGTGCCCGCGATCGCGATCGGCATCGCGACGATCCTCTATCTCGACA
ACAACATCCGCGGCGCGAAGTGGCTCACCGAGCGCGAGAAAAAACTGCTGGCCGACGAGATCGAAGCGCAGCCGCACGAG
CGCGACAAGCATGCGCATTCGCTTTCGACGGTGCTGCGCGATCCACGGACGTGGTGGATGTCGCTGATCTATTTCACGTT
CGTCACCGGCCAGTACGGGCTCACGTTCTGGATGCCCACGCTCGTCAAATCGACGGGCATCACCGATACGCTGCGCATCG
GCCTGCTGAGCGCGATTCCGTTCGCGTTCGCGATCGTCGCGATGAACCTGTTCGGCCGCAGCGCGGACAAGCGCCGCGAG
CGCCGCTGGCACCTGATCGTGCCCGCGCTGATGGGCACCGTCGGCTTCTCGGTGGCCGCCGCGTATTCGCACAACACCAC
CGTGTCGATCCTGTTCCTGTCGATCGCCGCGGGCGGCGTGCTCACCTGCGCGCCGCTCTTCTGGTCGCTGCCCACCGCGT
TTCTCGCGGGCACGGGCGCGGCCGCCGGCATCGCGATCATCAATTCGATCGGCAACCTCGCCGGCTTCGCGAGCCCCTAT
CTGATCGGCTATCTGAAGGACGCGACGAGCAGCACGTCGGCCGGCATGTACGTGCTCGCCGCGATGCTCGTGATCGGCGC
GCTCGCCGTGTGGCTCACACCGGCGAAGCTCGTCAACCGATAG

Upstream 100 bases:

>100_bases
AGTCCTGCCCGCCGTGTGCGCGGGCCCTCTCACCAGCACACGACAAAGCGCACGGCCGCGCGCAAGCGGCCGGCGTCGAC
AACTCATGGAGACAGCGAAA

Downstream 100 bases:

>100_bases
ATAATCGACCGTCGGCGGCGCCGCGCGCGTTCGGGCGCGCCCTCGCCGCCCCTTTCACCCACCGGACCTGGAACCGACGC
CATGCCGCGCTTCGCCGCCA

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIPSQAAAARPLEAAGQAELDLTYRKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGIFFLGYFL
FELPSNMLMHRIGARIWIARIMITWGLLSALFAFVKTPTQFYVLRFLLGLAEAGFYPGVILYLTYWFPTHRRAKIIAVFM
SAIPVSGIFGNPLSGWIMERFHGGSGFHGWQWMFVIEAVPAIAIGIATILYLDNNIRGAKWLTEREKKLLADEIEAQPHE
RDKHAHSLSTVLRDPRTWWMSLIYFTFVTGQYGLTFWMPTLVKSTGITDTLRIGLLSAIPFAFAIVAMNLFGRSADKRRE
RRWHLIVPALMGTVGFSVAAAYSHNTTVSILFLSIAAGGVLTCAPLFWSLPTAFLAGTGAAAGIAIINSIGNLAGFASPY
LIGYLKDATSSTSAGMYVLAAMLVIGALAVWLTPAKLVNR

Sequences:

>Translated_440_residues
MIPSQAAAARPLEAAGQAELDLTYRKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGIFFLGYFL
FELPSNMLMHRIGARIWIARIMITWGLLSALFAFVKTPTQFYVLRFLLGLAEAGFYPGVILYLTYWFPTHRRAKIIAVFM
SAIPVSGIFGNPLSGWIMERFHGGSGFHGWQWMFVIEAVPAIAIGIATILYLDNNIRGAKWLTEREKKLLADEIEAQPHE
RDKHAHSLSTVLRDPRTWWMSLIYFTFVTGQYGLTFWMPTLVKSTGITDTLRIGLLSAIPFAFAIVAMNLFGRSADKRRE
RRWHLIVPALMGTVGFSVAAAYSHNTTVSILFLSIAAGGVLTCAPLFWSLPTAFLAGTGAAAGIAIINSIGNLAGFASPY
LIGYLKDATSSTSAGMYVLAAMLVIGALAVWLTPAKLVNR
>Mature_440_residues
MIPSQAAAARPLEAAGQAELDLTYRKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGIFFLGYFL
FELPSNMLMHRIGARIWIARIMITWGLLSALFAFVKTPTQFYVLRFLLGLAEAGFYPGVILYLTYWFPTHRRAKIIAVFM
SAIPVSGIFGNPLSGWIMERFHGGSGFHGWQWMFVIEAVPAIAIGIATILYLDNNIRGAKWLTEREKKLLADEIEAQPHE
RDKHAHSLSTVLRDPRTWWMSLIYFTFVTGQYGLTFWMPTLVKSTGITDTLRIGLLSAIPFAFAIVAMNLFGRSADKRRE
RRWHLIVPALMGTVGFSVAAAYSHNTTVSILFLSIAAGGVLTCAPLFWSLPTAFLAGTGAAAGIAIINSIGNLAGFASPY
LIGYLKDATSSTSAGMYVLAAMLVIGALAVWLTPAKLVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=415, Percent_Identity=38.0722891566265, Blast_Score=277, Evalue=9e-76,
Organism=Escherichia coli, GI2367379, Length=440, Percent_Identity=23.8636363636364, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789515, Length=400, Percent_Identity=24, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082320, Length=423, Percent_Identity=24.822695035461, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789152, Length=443, Percent_Identity=24.1534988713318, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=323, Percent_Identity=26.0061919504644, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=231, Percent_Identity=27.7056277056277, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=294, Percent_Identity=25.5102040816327, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322612, Length=327, Percent_Identity=25.6880733944954, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323032, Length=244, Percent_Identity=27.0491803278689, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=177, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=156, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584153, Length=367, Percent_Identity=23.433242506812, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48577; Mature: 48577

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSQAAAARPLEAAGQAELDLTYRKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDL
CCCCCCHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
AFSETVFGLGAGIFFLGYFLFELPSNMLMHRIGARIWIARIMITWGLLSALFAFVKTPTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FYVLRFLLGLAEAGFYPGVILYLTYWFPTHRRAKIIAVFMSAIPVSGIFGNPLSGWIMER
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FHGGSGFHGWQWMFVIEAVPAIAIGIATILYLDNNIRGAKWLTEREKKLLADEIEAQPHE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCH
RDKHAHSLSTVLRDPRTWWMSLIYFTFVTGQYGLTFWMPTLVKSTGITDTLRIGLLSAIP
HHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
FAFAIVAMNLFGRSADKRRERRWHLIVPALMGTVGFSVAAAYSHNTTVSILFLSIAAGGV
HHHHHHHHHHHCCCHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
LTCAPLFWSLPTAFLAGTGAAAGIAIINSIGNLAGFASPYLIGYLKDATSSTSAGMYVLA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHH
AMLVIGALAVWLTPAKLVNR
HHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]