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The map label for this gene is 126446932

Identifier: 126446932

GI number: 126446932

Start: 834461

End: 835393

Strand: Direct

Name: 126446932

Synonym: BMA10247_A0881

Alternate gene names: NA

Gene position: 834461-835393 (Clockwise)

Preceding gene: 126445765

Following gene: 126445605

Centisome position: 35.47

GC content: 72.88

Gene sequence:

>933_bases
ATGAAGCACATCCACATCATCGATTCGCACACGGGCGGCGAACCCACGCGCGTCGTCGTGTCCGGCTTTCCGGCGCTCGG
CGGCGGCACGATGGCCGAGCGTCTGGCCGTGCTCGCGCGCGAGCACGACCGCTACCGCGCCGCCTGCATCCTCGAGCCGC
GCGGCAGCGACGTGCTCGTCGGCGCGCTGCTGTGCGAGCCCGTCTCGGCCGGCGCGGCGGCGGGCGTGATCTTCTTCAAC
AACGCGGGCTATCTCGGCATGTGCGGGCACGGCACGATCGGCCTCGTGCGCACGCTGCACCACATGGGGCGCATCGGGCC
GGGCGTGCATCGGATCGAGACGCCGGTGGGCGACGTCGAGGCGACGCTGCACGACGATCTGTCCGTGAGCGTGCGCAACG
TGCTCGTGTACCGGCACGCGAAGGACGTCGTCGTCGACGTGCCGGGGCACGGCGCGGTGACGGGCGACGTCGCGTGGGGC
GGCAACTGGTTCTTCCTCGTGAGCGATCACGGCCAGCGCGTCGCGGGCGAGAACGTCGCGGCGCTCGCCGCGTACGCGTC
GGCGGTGCGCGCGGCGCTCGAGCGCGCGGGCGTGACGGGCCGCGACGGCGCGCCGATCGATCACATCGAGCTGTTCGCCG
ACGATCCCGAGTACGACAGCCGCAGCTTCGTGCTCTGCCCGGGCCACGCGTACGACCGCTCGCCGTGCGGCACCGGCACG
AGCGCGAAGCTCGCGTGCCTCGCCGCCGACGGCAAGCTCGTGGCGGGCGTGACGTGGCGGCAGGCGAGCGTGATCGGCAG
CGTGTTCTCGGCGAGCTACGCGGCGGCCGAAGGCGGCGTCGTGCCGACGATCCGCGGCAGCGCGCACCTGAGCGCGGAGG
CGACGCTCGTGATCGAGGACGACGATCCGTTCGGCTGGGGCATCGCATCGTGA

Upstream 100 bases:

>100_bases
GGGCTGTGCCGATTTCGTCGCGCGCGTCATCGAAAACCCACAAGCGGCGCGATCCGCGACAAGGGAAGCTATGCGCATTT
CCACCCTGGATCGACGCGAC

Downstream 100 bases:

>100_bases
CCGATTCGCCGACCGACGTCATCGTGATCGGCGCGGGCATCGTCGGCGCCGCGTGCGCGCACGAGTTCGCGCTGCGCGGG
CTGCGCGTCGTCGTCGTCGA

Product: hydroxyproline-2-epimerase

Products: NA

Alternate protein names: Hydroxyproline-2-epimerase; BpHyPRE [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKHIHIIDSHTGGEPTRVVVSGFPALGGGTMAERLAVLAREHDRYRAACILEPRGSDVLVGALLCEPVSAGAAAGVIFFN
NAGYLGMCGHGTIGLVRTLHHMGRIGPGVHRIETPVGDVEATLHDDLSVSVRNVLVYRHAKDVVVDVPGHGAVTGDVAWG
GNWFFLVSDHGQRVAGENVAALAAYASAVRAALERAGVTGRDGAPIDHIELFADDPEYDSRSFVLCPGHAYDRSPCGTGT
SAKLACLAADGKLVAGVTWRQASVIGSVFSASYAAAEGGVVPTIRGSAHLSAEATLVIEDDDPFGWGIAS

Sequences:

>Translated_310_residues
MKHIHIIDSHTGGEPTRVVVSGFPALGGGTMAERLAVLAREHDRYRAACILEPRGSDVLVGALLCEPVSAGAAAGVIFFN
NAGYLGMCGHGTIGLVRTLHHMGRIGPGVHRIETPVGDVEATLHDDLSVSVRNVLVYRHAKDVVVDVPGHGAVTGDVAWG
GNWFFLVSDHGQRVAGENVAALAAYASAVRAALERAGVTGRDGAPIDHIELFADDPEYDSRSFVLCPGHAYDRSPCGTGT
SAKLACLAADGKLVAGVTWRQASVIGSVFSASYAAAEGGVVPTIRGSAHLSAEATLVIEDDDPFGWGIAS
>Mature_310_residues
MKHIHIIDSHTGGEPTRVVVSGFPALGGGTMAERLAVLAREHDRYRAACILEPRGSDVLVGALLCEPVSAGAAAGVIFFN
NAGYLGMCGHGTIGLVRTLHHMGRIGPGVHRIETPVGDVEATLHDDLSVSVRNVLVYRHAKDVVVDVPGHGAVTGDVAWG
GNWFFLVSDHGQRVAGENVAALAAYASAVRAALERAGVTGRDGAPIDHIELFADDPEYDSRSFVLCPGHAYDRSPCGTGT
SAKLACLAADGKLVAGVTWRQASVIGSVFSASYAAAEGGVVPTIRGSAHLSAEATLVIEDDDPFGWGIAS

Specific function: Allows intracellular utilization of 4-hydroxyproline, one of the major constituents of host collagen, by converting 4- hydroxy-L-proline to 4-hydroxy-D-proline, which can be further metabolized by intracellular 4-hydroxy-D-proline oxidases [H]

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family. 4- hydroxyproline epimerase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=335, Percent_Identity=30.7462686567164, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: =5.1.1.8 [H]

Molecular weight: Translated: 32175; Mature: 32175

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIHIIDSHTGGEPTRVVVSGFPALGGGTMAERLAVLAREHDRYRAACILEPRGSDVLV
CCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEE
GALLCEPVSAGAAAGVIFFNNAGYLGMCGHGTIGLVRTLHHMGRIGPGVHRIETPVGDVE
EEEECCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEE
ATLHDDLSVSVRNVLVYRHAKDVVVDVPGHGAVTGDVAWGGNWFFLVSDHGQRVAGENVA
EEECCCCEEEEEEEEEEEECCCEEEECCCCCEEEECEEECCEEEEEECCCCCCCCCCCHH
ALAAYASAVRAALERAGVTGRDGAPIDHIELFADDPEYDSRSFVLCPGHAYDRSPCGTGT
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCC
SAKLACLAADGKLVAGVTWRQASVIGSVFSASYAAAEGGVVPTIRGSAHLSAEATLVIED
CCEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCEEECCEEEEEEEC
DDPFGWGIAS
CCCCCCCCCC
>Mature Secondary Structure
MKHIHIIDSHTGGEPTRVVVSGFPALGGGTMAERLAVLAREHDRYRAACILEPRGSDVLV
CCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEE
GALLCEPVSAGAAAGVIFFNNAGYLGMCGHGTIGLVRTLHHMGRIGPGVHRIETPVGDVE
EEEECCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEE
ATLHDDLSVSVRNVLVYRHAKDVVVDVPGHGAVTGDVAWGGNWFFLVSDHGQRVAGENVA
EEECCCCEEEEEEEEEEEECCCEEEECCCCCEEEECEEECCEEEEEECCCCCCCCCCCHH
ALAAYASAVRAALERAGVTGRDGAPIDHIELFADDPEYDSRSFVLCPGHAYDRSPCGTGT
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCC
SAKLACLAADGKLVAGVTWRQASVIGSVFSASYAAAEGGVVPTIRGSAHLSAEATLVIED
CCEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCEEECCEEEEEEEC
DDPFGWGIAS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA