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The map label for this gene is plcH [H]

Identifier: 126446790

GI number: 126446790

Start: 1751796

End: 1753463

Strand: Direct

Name: plcH [H]

Synonym: BMA10247_A1822

Alternate gene names: 126446790

Gene position: 1751796-1753463 (Clockwise)

Preceding gene: 126446598

Following gene: 126447310

Centisome position: 74.46

GC content: 67.03

Gene sequence:

>1668_bases
ATGTTTCGTCGAGCCTGGATCGCCACCGCGTGCGCCGGATCGGCCATCGCCCTCTATGCGTGCGGCGGCACCGACAGCAA
CGCGCCCGTCACGTCGCAAAACGCATTGCGGACCGCGACGCCGATCAAGCATCTCGTCGTGATCTACGGCGAGAACGTGT
CGTTCGACCACTACTTCGGCACCTACCCGAACGCCGCGAACCCGCCGGGCGAGCCGGCGTTCAGCGCCGCGTCGGGCACG
CCGTCGATCAACGGCCTGTCGGGCCTGCTGCTCACCGCGAACCCGAACGCGACGAATCCGGCGAACGGCGCGGGCGCGAG
CAATCCGTTCCGCCTCGACCGCACACAGGCCGCGACGGCCGATCAGAACCACGCGTACACCGCCGAGGAGCAGGCGTACG
ACAACGGCCTCGCCGATCTCTTCCCGAAATACACGGGCAACGGCTCGAGCGGCGGCGCGGGCGCGTTCGGCACGACCGGC
CAGGTGATGGGTTACTTCGACGGCAACACGGTGACCGCGCTGTGGAACTACGCGCAGCGCTTCGCGATGAGCGACAACGC
ATACACGTCGACCTACGGCCCGTCGACGCCGGGCGCGCTGAACGTGATCGCCGGCCAGACCGACGGGATGCAGATCGTGA
AGACGTCGAAGGCCGTGTCGACGCTCGCGAAGACGTCGTACTACATCAACGACGGCCAGGGCGGCCTCACGATGATCAAC
GATGTCGACCCCGGCTACGACGTGTGCTCGAGCACGACCGATCAGGCGATGATGTCCGGCAAGAACATCGGCGATCTGCT
GAACGCGCGCAACGTCACGTGGGGCGGCTTCATGGGCGGCTTCAATCTGTCGACGACGAACGCGAACGGCACGACGGGCT
GCAAGCGCAGCACGATCGCGACCGCGGTGAACGCGGCGACGACCGACTACATCCCGCACCACAACTGGTTCCAGTACTAC
GCGTCGACCGCGAACCCGCAGCACACGCGCCCGAGCTCGATCGCGGCGATCGGCTCGAGCGTCCAGACGGACGGCAAGAC
GCCCGAGCCCGCGAATCACCAGTACGATTCGGACGACTTCTTCGCGGCCGTGAAGGCGGGCAACTTCCCGTCGGTCAGCT
TCCTGAAGGCGCCCGCCACGCAAGACGCGCACGCCGGCTACTCGGATCCGCTCGACGAGCAGCAGTTCGTGACGAAGGTC
GTCAACTTCCTGCAGCAGCAGCCCGACTGGGCGAGCACCGCGGTGATCGTCACGTATGACGACTCGGACGGCTGGTACGA
CCATGCGTACACCGCGCCGACGCGCGCGTCGTTCGATGCGGTCGACCAACTGAACGGCAACGGCGCGTGCGGCTCCGGCG
CCGCGACGACGGGCATCAACGGCGCCGCCGTCAACGGCCGCTGCGGTCCCGGCACGCGGATTCCGTTCGTCGTCGTGTCG
CCGTGGGCGAAGCAGAACTACGTGAGCCACACGCTGATCGATCAGGCGTCGGTCGTGCGCTTCATCGAGGACAACTGGCT
CGGCGGCCAGCGGATCGGCGGCGGCTCGTTCGATGCGACCGCGGGCAACATGCGCGATCTGTTCGATTTCTCGGGCGCGG
TGAACAAGACGCCGTTGTACCTCGATCCGACGCTCGGCACGAAGCTCGCAACCGCGCCTTCGATCTGA

Upstream 100 bases:

>100_bases
GCGCGTCCCCGACGCCCGCTCTCGCCGCGCGCCGGCTCCCGTCGGGCGACCCTTCGCGGATCGCCGTCAACCGAGCGATC
TTTCATTGGAGTCCTGTCTG

Downstream 100 bases:

>100_bases
GCGGTGCGCCGCGCACGCTCGGCGCGGCGCCGCCCGCACGCGACGCGCGCCCGATACATCACCGATGCACGGCCGGCCGG
CGCACGCAACGCCGGCCGTC

Product: phosphoesterase family protein

Products: NA

Alternate protein names: Heat-labile hemolysin; PLC-H; Phosphatidylcholine cholinephosphohydrolase [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MFRRAWIATACAGSAIALYACGGTDSNAPVTSQNALRTATPIKHLVVIYGENVSFDHYFGTYPNAANPPGEPAFSAASGT
PSINGLSGLLLTANPNATNPANGAGASNPFRLDRTQAATADQNHAYTAEEQAYDNGLADLFPKYTGNGSSGGAGAFGTTG
QVMGYFDGNTVTALWNYAQRFAMSDNAYTSTYGPSTPGALNVIAGQTDGMQIVKTSKAVSTLAKTSYYINDGQGGLTMIN
DVDPGYDVCSSTTDQAMMSGKNIGDLLNARNVTWGGFMGGFNLSTTNANGTTGCKRSTIATAVNAATTDYIPHHNWFQYY
ASTANPQHTRPSSIAAIGSSVQTDGKTPEPANHQYDSDDFFAAVKAGNFPSVSFLKAPATQDAHAGYSDPLDEQQFVTKV
VNFLQQQPDWASTAVIVTYDDSDGWYDHAYTAPTRASFDAVDQLNGNGACGSGAATTGINGAAVNGRCGPGTRIPFVVVS
PWAKQNYVSHTLIDQASVVRFIEDNWLGGQRIGGGSFDATAGNMRDLFDFSGAVNKTPLYLDPTLGTKLATAPSI

Sequences:

>Translated_555_residues
MFRRAWIATACAGSAIALYACGGTDSNAPVTSQNALRTATPIKHLVVIYGENVSFDHYFGTYPNAANPPGEPAFSAASGT
PSINGLSGLLLTANPNATNPANGAGASNPFRLDRTQAATADQNHAYTAEEQAYDNGLADLFPKYTGNGSSGGAGAFGTTG
QVMGYFDGNTVTALWNYAQRFAMSDNAYTSTYGPSTPGALNVIAGQTDGMQIVKTSKAVSTLAKTSYYINDGQGGLTMIN
DVDPGYDVCSSTTDQAMMSGKNIGDLLNARNVTWGGFMGGFNLSTTNANGTTGCKRSTIATAVNAATTDYIPHHNWFQYY
ASTANPQHTRPSSIAAIGSSVQTDGKTPEPANHQYDSDDFFAAVKAGNFPSVSFLKAPATQDAHAGYSDPLDEQQFVTKV
VNFLQQQPDWASTAVIVTYDDSDGWYDHAYTAPTRASFDAVDQLNGNGACGSGAATTGINGAAVNGRCGPGTRIPFVVVS
PWAKQNYVSHTLIDQASVVRFIEDNWLGGQRIGGGSFDATAGNMRDLFDFSGAVNKTPLYLDPTLGTKLATAPSI
>Mature_555_residues
MFRRAWIATACAGSAIALYACGGTDSNAPVTSQNALRTATPIKHLVVIYGENVSFDHYFGTYPNAANPPGEPAFSAASGT
PSINGLSGLLLTANPNATNPANGAGASNPFRLDRTQAATADQNHAYTAEEQAYDNGLADLFPKYTGNGSSGGAGAFGTTG
QVMGYFDGNTVTALWNYAQRFAMSDNAYTSTYGPSTPGALNVIAGQTDGMQIVKTSKAVSTLAKTSYYINDGQGGLTMIN
DVDPGYDVCSSTTDQAMMSGKNIGDLLNARNVTWGGFMGGFNLSTTNANGTTGCKRSTIATAVNAATTDYIPHHNWFQYY
ASTANPQHTRPSSIAAIGSSVQTDGKTPEPANHQYDSDDFFAAVKAGNFPSVSFLKAPATQDAHAGYSDPLDEQQFVTKV
VNFLQQQPDWASTAVIVTYDDSDGWYDHAYTAPTRASFDAVDQLNGNGACGSGAATTGINGAAVNGRCGPGTRIPFVVVS
PWAKQNYVSHTLIDQASVVRFIEDNWLGGQRIGGGSFDATAGNMRDLFDFSGAVNKTPLYLDPTLGTKLATAPSI

Specific function: Hydrolyzes sphingomyelin in addition to phosphatidylcholine [H]

COG id: COG3511

COG function: function code M; Phospholipase C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial phospholipase C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007312
- InterPro:   IPR008475
- InterPro:   IPR017767
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05506 DUF756; PF04185 Phosphoesterase [H]

EC number: =3.1.4.3 [H]

Molecular weight: Translated: 58140; Mature: 58140

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRRAWIATACAGSAIALYACGGTDSNAPVTSQNALRTATPIKHLVVIYGENVSFDHYFG
CCCHHEEHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCEEEEEEEECCCCCCCCCC
TYPNAANPPGEPAFSAASGTPSINGLSGLLLTANPNATNPANGAGASNPFRLDRTQAATA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCHHCCC
DQNHAYTAEEQAYDNGLADLFPKYTGNGSSGGAGAFGTTGQVMGYFDGNTVTALWNYAQR
CCCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEHHHHHHHHH
FAMSDNAYTSTYGPSTPGALNVIAGQTDGMQIVKTSKAVSTLAKTSYYINDGQGGLTMIN
HHCCCCCEECCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHEEEEECCCCCEEEEE
DVDPGYDVCSSTTDQAMMSGKNIGDLLNARNVTWGGFMGGFNLSTTNANGTTGCKRSTIA
CCCCCHHHHCCCHHHHHHCCCCHHHHHHCCCCEECCCCCCCEEEECCCCCCCCCCHHHHH
TAVNAATTDYIPHHNWFQYYASTANPQHTRPSSIAAIGSSVQTDGKTPEPANHQYDSDDF
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCE
FAAVKAGNFPSVSFLKAPATQDAHAGYSDPLDEQQFVTKVVNFLQQQPDWASTAVIVTYD
EEEEECCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEE
DSDGWYDHAYTAPTRASFDAVDQLNGNGACGSGAATTGINGAAVNGRCGPGTRIPFVVVS
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEC
PWAKQNYVSHTLIDQASVVRFIEDNWLGGQRIGGGSFDATAGNMRDLFDFSGAVNKTPLY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEE
LDPTLGTKLATAPSI
ECCCCCCCCCCCCCC
>Mature Secondary Structure
MFRRAWIATACAGSAIALYACGGTDSNAPVTSQNALRTATPIKHLVVIYGENVSFDHYFG
CCCHHEEHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCEEEEEEEECCCCCCCCCC
TYPNAANPPGEPAFSAASGTPSINGLSGLLLTANPNATNPANGAGASNPFRLDRTQAATA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCHHCCC
DQNHAYTAEEQAYDNGLADLFPKYTGNGSSGGAGAFGTTGQVMGYFDGNTVTALWNYAQR
CCCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEHHHHHHHHH
FAMSDNAYTSTYGPSTPGALNVIAGQTDGMQIVKTSKAVSTLAKTSYYINDGQGGLTMIN
HHCCCCCEECCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHEEEEECCCCCEEEEE
DVDPGYDVCSSTTDQAMMSGKNIGDLLNARNVTWGGFMGGFNLSTTNANGTTGCKRSTIA
CCCCCHHHHCCCHHHHHHCCCCHHHHHHCCCCEECCCCCCCEEEECCCCCCCCCCHHHHH
TAVNAATTDYIPHHNWFQYYASTANPQHTRPSSIAAIGSSVQTDGKTPEPANHQYDSDDF
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCE
FAAVKAGNFPSVSFLKAPATQDAHAGYSDPLDEQQFVTKVVNFLQQQPDWASTAVIVTYD
EEEEECCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEE
DSDGWYDHAYTAPTRASFDAVDQLNGNGACGSGAATTGINGAAVNGRCGPGTRIPFVVVS
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEC
PWAKQNYVSHTLIDQASVVRFIEDNWLGGQRIGGGSFDATAGNMRDLFDFSGAVNKTPLY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEE
LDPTLGTKLATAPSI
ECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3087958; 10984043 [H]