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The map label for this gene is nahR [H]

Identifier: 126446781

GI number: 126446781

Start: 2236068

End: 2237135

Strand: Direct

Name: nahR [H]

Synonym: BMA10247_A2309

Alternate gene names: 126446781

Gene position: 2236068-2237135 (Clockwise)

Preceding gene: 126447633

Following gene: 126445854

Centisome position: 95.04

GC content: 69.94

Gene sequence:

>1068_bases
TTGCAAACGCCGCTCATGCCTGTCGCACCCGCCGCGCCCACCGTGCGCGCGCAAGCGTCGGGCGCGCGCGCATGCCCGCG
CCGCCCTCGCGCATCCGGCGCGCCGCCTGCCCCCATTCCGGAGCGCCGCCGTATGATCCAGAATCTGCGACAGCTCGACC
TGAACCTGCTGCTCGTGTTCGACGCGCTGATGCAGGAGCAGAACCTGTCGCGCGCCGCCATCCGGCTGCACATGAGCCAG
CCGGCCGTCAGCAATGCGCTGACGCGGCTGCGTCAGCAGCTCGGCGAGCCGCTCTTCACGCGCACCGCGCGCGGCATGAC
GCCGACCGCGCAGGCGCGCACGCTGTACGAGCCGGTCCGCCAGGCGCTGTATCTGCTGCAGATCGGGCTCGGCCCGCAAG
CCGATTTCGAGCCCGACACGCACCACCTGTTCAAGCTGTCGATGAACGATTACGGGCAAACGGTGCTGCTGCCCGATCTG
CTCGCGCACATCAAGTCGCGCGCGCCGAACGTGATGCTCTCGGTGCAGAGCGACGACGCCGGCTCGATTCCCGCGCAACT
GACGACGGGCACGCTCGATCTCGCGATCGACTACCTGCATTTCGACAATCCGGAGCTCTGCTACGAGCCGCTGCACGAGG
AGCACCTCGTCGTGATCGGGCGCGCCGGCCATCCGGCGTTCGCCGGCGGGCTCGCGCTGCGCGGCTACGAGGAGAGCGGG
CACGTGTCGATCCAGCCGCGCGACAGGCGCGGCTCGCCGCTCGAGATCGTGCTCGGCTCCGCGCGCGTGCGGCGCGTCGT
GCATCTGCAGGTGCCGCACTATCTGACGATTCCCGCGCTCGTCGCGAAATCGGACCTGCTCGGCACGATCCCGCGCCGGC
TCGCCGAGCGGTTCGCCGATGTCTATGCGCTGCAGATCGCGCCGCTGCCGATCGACATCGCGCCGATCCAGGTGAGCCTC
ATCTGGCATCGTCAGCAGGATGCGCAGCCCGGCCTGCGCTGGCTGCGCGAGCAGGTCGTTCTCACGCATCGCGCGATCAT
CGGATGCGGCGAGCACGCGCCGGCGTGA

Upstream 100 bases:

>100_bases
GTAGCCCCGATGATTTCTCCAATGGACAATCGTGATTTGACTTATTCACCGATCTGAATTCGATCATGCGCCGCGCCGAT
ATGTCGAACGATCCCGTCGA

Downstream 100 bases:

>100_bases
CAGGCGTCGTGCGAGATGTGCCGCGCGCGCGGCATCGGCCGCCAGGCACGCGGCAACGCGACCGCGCCGTCGCCGATCGC
GGCCGCCGCGATCGGCGCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQTPLMPVAPAAPTVRAQASGARACPRRPRASGAPPAPIPERRRMIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQ
PAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDL
LAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESG
HVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSL
IWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA

Sequences:

>Translated_355_residues
MQTPLMPVAPAAPTVRAQASGARACPRRPRASGAPPAPIPERRRMIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQ
PAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDL
LAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESG
HVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSL
IWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>Mature_355_residues
MQTPLMPVAPAAPTVRAQASGARACPRRPRASGAPPAPIPERRRMIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQ
PAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDL
LAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESG
HVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSL
IWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=293, Percent_Identity=35.1535836177474, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87081766, Length=286, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790147, Length=301, Percent_Identity=24.5847176079734, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786820, Length=264, Percent_Identity=23.1060606060606, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=251, Percent_Identity=23.1075697211155, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI157672245, Length=166, Percent_Identity=28.3132530120482, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 39204; Mature: 39204

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPLMPVAPAAPTVRAQASGARACPRRPRASGAPPAPIPERRRMIQNLRQLDLNLLLVF
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
DALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVR
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHH
QALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDA
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEEEECCCC
GSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESG
CCCCCEEECCCCEEEEEEEECCCHHHHHCCCCCCCEEEEECCCCCCHHCCEEEECCCCCC
HVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFAD
EEEEEECCCCCCCEEEEECCHHHEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
EEEEEEECCCEEECCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MQTPLMPVAPAAPTVRAQASGARACPRRPRASGAPPAPIPERRRMIQNLRQLDLNLLLVF
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
DALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVR
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHH
QALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDA
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEEEECCCC
GSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESG
CCCCCEEECCCCEEEEEEEECCCHHHHHCCCCCCCEEEEECCCCCCHHCCEEEECCCCCC
HVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFAD
EEEEEECCCCCCCEEEEECCHHHEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
EEEEEEECCCEEECCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]