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The map label for this gene is fusC [H]

Identifier: 126446778

GI number: 126446778

Start: 1770317

End: 1772554

Strand: Direct

Name: fusC [H]

Synonym: BMA10247_A1840

Alternate gene names: 126446778

Gene position: 1770317-1772554 (Clockwise)

Preceding gene: 126446930

Following gene: 126447302

Centisome position: 75.25

GC content: 70.38

Gene sequence:

>2238_bases
ATGAAGCACGAGCCCGCGCTACAGCGATTCCCCATCGACCCGCACCGATGGCAGGAGCGGCTGCGAAGCACCGGCAGGCT
CGCGCGCGACTGGGCGGGCCGCGACGGCCTCGTCTGGCTGCATCTCGCGAAAACGGTGGCCGCCGCGCTGCTCGCGATGG
GCATCGCGATGCTGCTCGATCTATCGCAGCCGCGCATCGCGATGACGACCGTGTTCGTGCTGATGCAGCCGATGAGCGGG
ATGGTGCTCGCGAAGAGTTTCTACCGCGTCGTCGGCACGGGCGTCGGGCTCGTGGCGGCGCTCGCGCTCGGCGGCCTGTT
CGCGCAGCAGCCGGAGCTATACATGGCGGGCATCACGCTGTGGGTCGCGGGCTGCATCGCGGCGGCCGTGCGCAACCGGC
ACTTTCGCTGGTACGGCTACGTGCTCGCCGGCTACACCGCCGCGCTGATCGGCCTGCCCGCGGTGATGGCGCCGAACACG
CTGTTTCTGTCGGCGCTCACGCGCGCGGCCGAAGTCGCGGTCGGCATCTTCTGCTCGGGCGCCGTCAGCGCGCTCGTGCT
TCCGCTCAGCTCGAGCGATGCGCTGATGCGCACGCTGAGCGCGCGGCACGCCGATTTCGTCGCGTTCGCGGCGAGCACGA
CGGCGGGCGCGGTCGAGCGCGGCGAGTTCGAGCGGCGCTTCGCCGACTTCGTCGACGGCATCGTCGGCTTCGAGGCGACG
CGCGCGTTCGCGACCTTCGAGGATCCGTACATCCGCGCGCGCAGCCGCCGGCTCGCGCGGCTGAACAGCGAGTTCATGAA
CGCATGCGCGCGCCTCCATGCATTCCATCAGTTGCTCAGGCGCCTGCGCGCGAATCATGCGGCCGAGGTGCTCACGGCGA
TCGCCCCGCATGTCGATGCGCTGTCGGGCGTGCTGTACGCGCTGCGCGCCGATCTCGCGCGGCCACGCGCGCGATCGGCG
CCGTCGCCGTCGCCGTCGCCTTCGCCTGCGCTCGTCGCGCTGAGTGCGTATCTGGCCGCGCTGCCCAAGCGCGCGCGCGC
ATCGCGCCGCGGGCTCGAGACGCTCGCACCCGCCGGCGTGCTCGACTTCGATACCGCGATCGAGCTGCTCTACCGCTTCG
TCGACGAATTCCTCGGCTACGCGGAAACGCACGCGTCGCTCGCGCTCGACAGTCACGTGCTCGAACGTTCGGTCACGCGG
TATGCGGTGAAGACCAACCGCTACTTCGTCGGCTTCACGTTCCTGCGCACGCTCGTCGCGATGGGTGCGATGAGCGCGTT
CTGGATCGCGTCCGAATGGTCGAGCGGCTCGCTCGCCGTGATCGGCACCGCGATCGCGTGCGCGCTCAGCTCGACCGCGC
CGCGCGCGAGCCGCTTCGTCGCGCAGATGGCCGCCGGCGCGGCGCTCGCCACGCTCACGGGTTACCTGTACGTGTGCCGC
GTGTATCCGAACATCGACGGCTTCCCGCTGCTGTGCGCGGCGCTCGCGCCCGTGCTCGCGGCGGGCGCGTATCTCGCGAC
GCGTCCGGGCAAGTCCGGCTACGGGATCGGCTTCGTCGTGTTCTTCTGCCTGCTCGCGGGGCCGGACAACGTGATCGTCT
ACGCGCCCGACGTGCTGATCAACAACGGGCTCGCGCTCGTCGTGTCGATGCTCGCCGCATCGATCGCGTTCGCGGTGGTG
TTTCCCGCCGAGATGCCGTGGCTCACCGGCCGGATCGCGCGCGACCTGCGCCGGCAGATCGCGCTCGCGTGCGACGGCCC
GCTGCAAGGGCTCGATCAGCGCTTTCAGTCGAGCTCGCACGATCTGATGTCGCAACTGCGCAATCTGCTGATGAAGCGCT
CACGGCGGCATCGGGACGCGCTTCGCTGGATGCTCGCGACGCTCGAAATCGGCCACGCGGTGATCGATCTGCGGCGCGAG
ATGCAGGCGTTCACGGCCGCGCAACCCGCGCAGGCGCTGCGCTGGCGCGCGTTGATCGACGCGGTGCGCGAGGCGCTGCC
GAGGCTGTTCGAGACGCCCGACGCGCACCGCCTCGCGCGTGCGCTGAAGTCGGTCAATCTCGCGATCCGCGCGGTCCGGC
ACACGCAGCACCTGTGGTACGCGGTGCCCGACGAGCGGCGCCGGATGCAGCGCATCGTCAGTTGCCTGCACTTCATCCGC
AGCGCGCTGATCGATCAGGACGCGCCGTTCAATCGCGGCTCGCGCGCCCGCGAACGCGTGCGCGCAAGGCGCATGTGA

Upstream 100 bases:

>100_bases
GGCTCCTACAATCGGCGCCTCTCCGGTCAGACTGGCGTCGTCGCGCGAGGCCGGAGGCCCCCGATCCGCGCCCGCCAGAA
GCACCGCCCCGCCCACTGCC

Downstream 100 bases:

>100_bases
CGTGCGAAACGATCGTTGTGCGAAATGGAAGGAAGCTCCGCAGGCCGGGCGATTAATCCAAACCCGGCCGAGTCATATAG
TTTCATCACCGTCGAGCAAG

Product: fusaric acid resistance domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 745; Mature: 745

Protein sequence:

>745_residues
MKHEPALQRFPIDPHRWQERLRSTGRLARDWAGRDGLVWLHLAKTVAAALLAMGIAMLLDLSQPRIAMTTVFVLMQPMSG
MVLAKSFYRVVGTGVGLVAALALGGLFAQQPELYMAGITLWVAGCIAAAVRNRHFRWYGYVLAGYTAALIGLPAVMAPNT
LFLSALTRAAEVAVGIFCSGAVSALVLPLSSSDALMRTLSARHADFVAFAASTTAGAVERGEFERRFADFVDGIVGFEAT
RAFATFEDPYIRARSRRLARLNSEFMNACARLHAFHQLLRRLRANHAAEVLTAIAPHVDALSGVLYALRADLARPRARSA
PSPSPSPSPALVALSAYLAALPKRARASRRGLETLAPAGVLDFDTAIELLYRFVDEFLGYAETHASLALDSHVLERSVTR
YAVKTNRYFVGFTFLRTLVAMGAMSAFWIASEWSSGSLAVIGTAIACALSSTAPRASRFVAQMAAGAALATLTGYLYVCR
VYPNIDGFPLLCAALAPVLAAGAYLATRPGKSGYGIGFVVFFCLLAGPDNVIVYAPDVLINNGLALVVSMLAASIAFAVV
FPAEMPWLTGRIARDLRRQIALACDGPLQGLDQRFQSSSHDLMSQLRNLLMKRSRRHRDALRWMLATLEIGHAVIDLRRE
MQAFTAAQPAQALRWRALIDAVREALPRLFETPDAHRLARALKSVNLAIRAVRHTQHLWYAVPDERRRMQRIVSCLHFIR
SALIDQDAPFNRGSRARERVRARRM

Sequences:

>Translated_745_residues
MKHEPALQRFPIDPHRWQERLRSTGRLARDWAGRDGLVWLHLAKTVAAALLAMGIAMLLDLSQPRIAMTTVFVLMQPMSG
MVLAKSFYRVVGTGVGLVAALALGGLFAQQPELYMAGITLWVAGCIAAAVRNRHFRWYGYVLAGYTAALIGLPAVMAPNT
LFLSALTRAAEVAVGIFCSGAVSALVLPLSSSDALMRTLSARHADFVAFAASTTAGAVERGEFERRFADFVDGIVGFEAT
RAFATFEDPYIRARSRRLARLNSEFMNACARLHAFHQLLRRLRANHAAEVLTAIAPHVDALSGVLYALRADLARPRARSA
PSPSPSPSPALVALSAYLAALPKRARASRRGLETLAPAGVLDFDTAIELLYRFVDEFLGYAETHASLALDSHVLERSVTR
YAVKTNRYFVGFTFLRTLVAMGAMSAFWIASEWSSGSLAVIGTAIACALSSTAPRASRFVAQMAAGAALATLTGYLYVCR
VYPNIDGFPLLCAALAPVLAAGAYLATRPGKSGYGIGFVVFFCLLAGPDNVIVYAPDVLINNGLALVVSMLAASIAFAVV
FPAEMPWLTGRIARDLRRQIALACDGPLQGLDQRFQSSSHDLMSQLRNLLMKRSRRHRDALRWMLATLEIGHAVIDLRRE
MQAFTAAQPAQALRWRALIDAVREALPRLFETPDAHRLARALKSVNLAIRAVRHTQHLWYAVPDERRRMQRIVSCLHFIR
SALIDQDAPFNRGSRARERVRARRM
>Mature_745_residues
MKHEPALQRFPIDPHRWQERLRSTGRLARDWAGRDGLVWLHLAKTVAAALLAMGIAMLLDLSQPRIAMTTVFVLMQPMSG
MVLAKSFYRVVGTGVGLVAALALGGLFAQQPELYMAGITLWVAGCIAAAVRNRHFRWYGYVLAGYTAALIGLPAVMAPNT
LFLSALTRAAEVAVGIFCSGAVSALVLPLSSSDALMRTLSARHADFVAFAASTTAGAVERGEFERRFADFVDGIVGFEAT
RAFATFEDPYIRARSRRLARLNSEFMNACARLHAFHQLLRRLRANHAAEVLTAIAPHVDALSGVLYALRADLARPRARSA
PSPSPSPSPALVALSAYLAALPKRARASRRGLETLAPAGVLDFDTAIELLYRFVDEFLGYAETHASLALDSHVLERSVTR
YAVKTNRYFVGFTFLRTLVAMGAMSAFWIASEWSSGSLAVIGTAIACALSSTAPRASRFVAQMAAGAALATLTGYLYVCR
VYPNIDGFPLLCAALAPVLAAGAYLATRPGKSGYGIGFVVFFCLLAGPDNVIVYAPDVLINNGLALVVSMLAASIAFAVV
FPAEMPWLTGRIARDLRRQIALACDGPLQGLDQRFQSSSHDLMSQLRNLLMKRSRRHRDALRWMLATLEIGHAVIDLRRE
MQAFTAAQPAQALRWRALIDAVREALPRLFETPDAHRLARALKSVNLAIRAVRHTQHLWYAVPDERRRMQRIVSCLHFIR
SALIDQDAPFNRGSRARERVRARRM

Specific function: Involved in the resistance (detoxification) of the fungal toxin fusaric acid [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1787933, Length=614, Percent_Identity=26.2214983713355, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789636, Length=470, Percent_Identity=20.8510638297872, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 81548; Mature: 81548

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHEPALQRFPIDPHRWQERLRSTGRLARDWAGRDGLVWLHLAKTVAAALLAMGIAMLLD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
LSQPRIAMTTVFVLMQPMSGMVLAKSFYRVVGTGVGLVAALALGGLFAQQPELYMAGITL
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHH
WVAGCIAAAVRNRHFRWYGYVLAGYTAALIGLPAVMAPNTLFLSALTRAAEVAVGIFCSG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
AVSALVLPLSSSDALMRTLSARHADFVAFAASTTAGAVERGEFERRFADFVDGIVGFEAT
HHHHHEECCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFATFEDPYIRARSRRLARLNSEFMNACARLHAFHQLLRRLRANHAAEVLTAIAPHVDA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVLYALRADLARPRARSAPSPSPSPSPALVALSAYLAALPKRARASRRGLETLAPAGV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCC
LDFDTAIELLYRFVDEFLGYAETHASLALDSHVLERSVTRYAVKTNRYFVGFTFLRTLVA
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
MGAMSAFWIASEWSSGSLAVIGTAIACALSSTAPRASRFVAQMAAGAALATLTGYLYVCR
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VYPNIDGFPLLCAALAPVLAAGAYLATRPGKSGYGIGFVVFFCLLAGPDNVIVYAPDVLI
ECCCCCCHHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHH
NNGLALVVSMLAASIAFAVVFPAEMPWLTGRIARDLRRQIALACDGPLQGLDQRFQSSSH
HCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHH
DLMSQLRNLLMKRSRRHRDALRWMLATLEIGHAVIDLRREMQAFTAAQPAQALRWRALID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AVREALPRLFETPDAHRLARALKSVNLAIRAVRHTQHLWYAVPDERRRMQRIVSCLHFIR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHH
SALIDQDAPFNRGSRARERVRARRM
HHHCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKHEPALQRFPIDPHRWQERLRSTGRLARDWAGRDGLVWLHLAKTVAAALLAMGIAMLLD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
LSQPRIAMTTVFVLMQPMSGMVLAKSFYRVVGTGVGLVAALALGGLFAQQPELYMAGITL
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHH
WVAGCIAAAVRNRHFRWYGYVLAGYTAALIGLPAVMAPNTLFLSALTRAAEVAVGIFCSG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
AVSALVLPLSSSDALMRTLSARHADFVAFAASTTAGAVERGEFERRFADFVDGIVGFEAT
HHHHHEECCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFATFEDPYIRARSRRLARLNSEFMNACARLHAFHQLLRRLRANHAAEVLTAIAPHVDA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVLYALRADLARPRARSAPSPSPSPSPALVALSAYLAALPKRARASRRGLETLAPAGV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCC
LDFDTAIELLYRFVDEFLGYAETHASLALDSHVLERSVTRYAVKTNRYFVGFTFLRTLVA
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHH
MGAMSAFWIASEWSSGSLAVIGTAIACALSSTAPRASRFVAQMAAGAALATLTGYLYVCR
HHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VYPNIDGFPLLCAALAPVLAAGAYLATRPGKSGYGIGFVVFFCLLAGPDNVIVYAPDVLI
ECCCCCCHHHHHHHHHHHHHHCCHHEECCCCCCCCHHHHHHHHHHCCCCCEEEEECHHHH
NNGLALVVSMLAASIAFAVVFPAEMPWLTGRIARDLRRQIALACDGPLQGLDQRFQSSSH
HCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHH
DLMSQLRNLLMKRSRRHRDALRWMLATLEIGHAVIDLRREMQAFTAAQPAQALRWRALID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AVREALPRLFETPDAHRLARALKSVNLAIRAVRHTQHLWYAVPDERRRMQRIVSCLHFIR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHH
SALIDQDAPFNRGSRARERVRARRM
HHHCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1370369 [H]