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The map label for this gene is ycgM [H]

Identifier: 126446757

GI number: 126446757

Start: 1124683

End: 1125387

Strand: Reverse

Name: ycgM [H]

Synonym: BMA10247_A1149

Alternate gene names: 126446757

Gene position: 1125387-1124683 (Counterclockwise)

Preceding gene: 126446059

Following gene: 126446123

Centisome position: 47.83

GC content: 72.06

Gene sequence:

>705_bases
ATGACCGATTACGTTTTTGCGCCGCCCGCCGTGCCGTCCGTCGAGATCGCCGGCTGCGCCGCGCGCTTTGCGGTGCGCCG
CGTGTTCTGCGTCGGCCGCAACTATGCGGACCACGCGCGCGAGATGGGCGCCGATCCGAACCGCGAGCCGCCGTTCTTCT
TCACGAAGCCGGCCGACGCGATCGTGCCCGCGAGCGGCACGGTGCCATACCCGACGCTCACGTCCGAGCTGCATCACGAG
ATCGAACTCGTGATCGCGATCGGCCGCGGCGGGCGCGCGATCGCCGCCGACGCGGCGCTCGATCACGTGTGGGGCTATGG
CGTCGGCGTCGACCTGACGCGGCGCGACTTGCAGGCCGAGGCGAAGAAGGCCGGCAGGCCGTGGGACTGGGCGAAGGGCT
TCGACGCGTCGGGCCCGGTGACGGCGCTGCATCCGGCCGCGTCGATCGGCCATCCGCAGCGCGGCCGGATCTGGCTCGCC
GTGAACGGCGCCTTGCGCCAGCAAGGCGATCTCGCCGACATGATCTGGCCGATCCCCGACGTGATCGCGTATGCGTCGCG
CGCGGTCGAACTGCGCGCGGGCGACCTGATCTTCACCGGCACGCCGGCGGGCGTCGCCGCGCTGCAGCCGGGCGAGCGCG
TGACGGGCGGCGTCGACGGCGTCGCGTCGTTCGAGTTCGTCGTCGGAGAAAAACCGGCCGCGTGA

Upstream 100 bases:

>100_bases
CCGCGCCCGCCCCGGCGCGCGGCCGGGCAGCGCACCGCCCGCACGCGCCGTCGCTTTCGCTTTCGCTTTCACTTTTCGAC
ACCTTTTCAGAGACCCGAAG

Downstream 100 bases:

>100_bases
GCCGCCTCGCCGCTCCCGCTTCGCCGTTTTCCCTCCGGAGGCTGTCCGCTTGGGGCGTGCCCGGCGCGCGCCGCCCGCCC
GGGCCCCGCACGGGCGGCAT

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTDYVFAPPAVPSVEIAGCAARFAVRRVFCVGRNYADHAREMGADPNREPPFFFTKPADAIVPASGTVPYPTLTSELHHE
IELVIAIGRGGRAIAADAALDHVWGYGVGVDLTRRDLQAEAKKAGRPWDWAKGFDASGPVTALHPAASIGHPQRGRIWLA
VNGALRQQGDLADMIWPIPDVIAYASRAVELRAGDLIFTGTPAGVAALQPGERVTGGVDGVASFEFVVGEKPAA

Sequences:

>Translated_234_residues
MTDYVFAPPAVPSVEIAGCAARFAVRRVFCVGRNYADHAREMGADPNREPPFFFTKPADAIVPASGTVPYPTLTSELHHE
IELVIAIGRGGRAIAADAALDHVWGYGVGVDLTRRDLQAEAKKAGRPWDWAKGFDASGPVTALHPAASIGHPQRGRIWLA
VNGALRQQGDLADMIWPIPDVIAYASRAVELRAGDLIFTGTPAGVAALQPGERVTGGVDGVASFEFVVGEKPAA
>Mature_233_residues
TDYVFAPPAVPSVEIAGCAARFAVRRVFCVGRNYADHAREMGADPNREPPFFFTKPADAIVPASGTVPYPTLTSELHHEI
ELVIAIGRGGRAIAADAALDHVWGYGVGVDLTRRDLQAEAKKAGRPWDWAKGFDASGPVTALHPAASIGHPQRGRIWLAV
NGALRQQGDLADMIWPIPDVIAYASRAVELRAGDLIFTGTPAGVAALQPGERVTGGVDGVASFEFVVGEKPAA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=44.4444444444444, Blast_Score=191, Evalue=6e-49,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=43.8775510204082, Blast_Score=184, Evalue=4e-47,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=43.8775510204082, Blast_Score=184, Evalue=5e-47,
Organism=Homo sapiens, GI156231349, Length=202, Percent_Identity=35.1485148514851, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI40786394, Length=202, Percent_Identity=34.1584158415842, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1787428, Length=204, Percent_Identity=43.6274509803922, Blast_Score=165, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17557057, Length=208, Percent_Identity=35.5769230769231, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=245, Percent_Identity=32.6530612244898, Blast_Score=136, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571789, Length=205, Percent_Identity=34.1463414634146, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28572127, Length=208, Percent_Identity=31.7307692307692, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24663695, Length=208, Percent_Identity=27.4038461538462, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24759; Mature: 24628

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYVFAPPAVPSVEIAGCAARFAVRRVFCVGRNYADHAREMGADPNREPPFFFTKPADA
CCCCEECCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEECCCCC
IVPASGTVPYPTLTSELHHEIELVIAIGRGGRAIAADAALDHVWGYGVGVDLTRRDLQAE
EECCCCCCCCCCHHHHHCCEEEEEEEECCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHH
AKKAGRPWDWAKGFDASGPVTALHPAASIGHPQRGRIWLAVNGALRQQGDLADMIWPIPD
HHHCCCCCCHHCCCCCCCCEEEECCHHHCCCCCCCEEEEEECCCHHCCCCHHHHHCCHHH
VIAYASRAVELRAGDLIFTGTPAGVAALQPGERVTGGVDGVASFEFVVGEKPAA
HHHHHHHHEEEECCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TDYVFAPPAVPSVEIAGCAARFAVRRVFCVGRNYADHAREMGADPNREPPFFFTKPADA
CCCEECCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEECCCCC
IVPASGTVPYPTLTSELHHEIELVIAIGRGGRAIAADAALDHVWGYGVGVDLTRRDLQAE
EECCCCCCCCCCHHHHHCCEEEEEEEECCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHH
AKKAGRPWDWAKGFDASGPVTALHPAASIGHPQRGRIWLAVNGALRQQGDLADMIWPIPD
HHHCCCCCCHHCCCCCCCCEEEECCHHHCCCCCCCEEEEEECCCHHCCCCHHHHHCCHHH
VIAYASRAVELRAGDLIFTGTPAGVAALQPGERVTGGVDGVASFEFVVGEKPAA
HHHHHHHHEEEECCCEEEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]