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The map label for this gene is hipO-1 [H]

Identifier: 126446703

GI number: 126446703

Start: 730648

End: 731835

Strand: Direct

Name: hipO-1 [H]

Synonym: BMA10247_A0794

Alternate gene names: 126446703

Gene position: 730648-731835 (Clockwise)

Preceding gene: 126445855

Following gene: 126446162

Centisome position: 31.06

GC content: 70.71

Gene sequence:

>1188_bases
ATGAACGACGCACGTTTTACCGAGGTCGACGACCTCGCCCCGCTCGCCGAAGCACTGCGCGAGATCCGCCATCGCATCCA
CCGCCATCCGGAACTCGCGTACGAGGAGGTCGAGACGGCCGCGCTCGTCGCGGACAAGCTCGAAGCCTGGGGCTGGCGGG
TGACGCGCGGCGTGGGCGGCACGGGCGTGGTCGGCACGCTGCGCGTGGGCGACGGCGCGCGCAGCGTCGGCGTGCGCGCG
GACATGGACGCGCTGCCGATCGCCGAGGCGACCGGGCTGCCTTATGCGAGCGCGGTGCCCGGCAAGATGCACGCGTGCGG
CCACGACGGCCACACTGCGATGCTGCTCGGCGCCGCATGGCGGCTCGCGCAGGCGCGCCACTTCTCCGGCACCGTTCATC
TGTATTTTCAGCCGGCCGAGGAGCACGGCGTCGACAGCGGCGCGAAGCGCATGATCGACGACGGCCTTTTCGAGCGCTTT
CCGTGCGACGCGGTGTTCGGGATGCACAACCATCCGGGCGTCGAGCCGGGCGTGTTCCTCACGCGGCGGGGGGCGTTCAT
GTCGGCGGGCGACAAGGCGGTGATCGACATCCACGGCGTGGGCGGCCATGCGGCGCGGCCGCATCTGGCGGTCGATCCGG
TCGTCGTCGCGGCGAGCGTCGTGATGGCGCTGCAGACGATCGTCGCGCGCAACGTCGATCCCGCGCAGCCCGCCGTCGTG
ACGGTCGGCTCGCTGCACGCCGGCACCGCGAACAACGTCATTCCGAGCCGCGCGCGGCTCGAGCTCTCCGTGCGCTCGTT
CGATCCCGAGGTGCGCGCGCTGCTCAGGCGCCGGATCACCGAGCTCGCCCAGGCGCAGGCGGCCAGCTACGGCGCGAGCG
CGAACGTCGAGTACATCGAGGGCTACCCGGTCGTCGTCAATTCGGACGCCGAAACCGACTTCGCCGCGCAGGTCGCGAAG
GAGCTGGTGGGCGAGCGCAATGTCGTCGAGCAGGCCGACATCCTGATGGGCAGCGAGGATTTCGCGTTCATGCTGCAGCG
GCGGCCGGGCTCGTTCGTGCGGCTCGGCAACGGCGCGGGCGAGGAAGGCTGCATGGTGCACAACCCGAAATACGACTTCA
ACGATCGCAACCTCGTGACGGGCGCGGCGTTCTGGGCGCGGCTCGTCGAGCGGTATCTGGCGCGGTAG

Upstream 100 bases:

>100_bases
CGGTGAAAAAAACGGCATCTTATTGAATCGTTATGGCGTCGCTATAGTGCCCCCTCCTGCGCGTCCGATTGCCCGGACGC
CGCCGTCACGGAGCCTTTCG

Downstream 100 bases:

>100_bases
GCGGCAGGCGGCGCGGGTGGGGCGTTGGTGGCAAACGGCGGGCGGCAAGTGACGAGTGCCGAGCAGCAAGCGACAAGCGA
TGAACGGCCGACGCCAGTCG

Product: hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNDARFTEVDDLAPLAEALREIRHRIHRHPELAYEEVETAALVADKLEAWGWRVTRGVGGTGVVGTLRVGDGARSVGVRA
DMDALPIAEATGLPYASAVPGKMHACGHDGHTAMLLGAAWRLAQARHFSGTVHLYFQPAEEHGVDSGAKRMIDDGLFERF
PCDAVFGMHNHPGVEPGVFLTRRGAFMSAGDKAVIDIHGVGGHAARPHLAVDPVVVAASVVMALQTIVARNVDPAQPAVV
TVGSLHAGTANNVIPSRARLELSVRSFDPEVRALLRRRITELAQAQAASYGASANVEYIEGYPVVVNSDAETDFAAQVAK
ELVGERNVVEQADILMGSEDFAFMLQRRPGSFVRLGNGAGEEGCMVHNPKYDFNDRNLVTGAAFWARLVERYLAR

Sequences:

>Translated_395_residues
MNDARFTEVDDLAPLAEALREIRHRIHRHPELAYEEVETAALVADKLEAWGWRVTRGVGGTGVVGTLRVGDGARSVGVRA
DMDALPIAEATGLPYASAVPGKMHACGHDGHTAMLLGAAWRLAQARHFSGTVHLYFQPAEEHGVDSGAKRMIDDGLFERF
PCDAVFGMHNHPGVEPGVFLTRRGAFMSAGDKAVIDIHGVGGHAARPHLAVDPVVVAASVVMALQTIVARNVDPAQPAVV
TVGSLHAGTANNVIPSRARLELSVRSFDPEVRALLRRRITELAQAQAASYGASANVEYIEGYPVVVNSDAETDFAAQVAK
ELVGERNVVEQADILMGSEDFAFMLQRRPGSFVRLGNGAGEEGCMVHNPKYDFNDRNLVTGAAFWARLVERYLAR
>Mature_395_residues
MNDARFTEVDDLAPLAEALREIRHRIHRHPELAYEEVETAALVADKLEAWGWRVTRGVGGTGVVGTLRVGDGARSVGVRA
DMDALPIAEATGLPYASAVPGKMHACGHDGHTAMLLGAAWRLAQARHFSGTVHLYFQPAEEHGVDSGAKRMIDDGLFERF
PCDAVFGMHNHPGVEPGVFLTRRGAFMSAGDKAVIDIHGVGGHAARPHLAVDPVVVAASVVMALQTIVARNVDPAQPAVV
TVGSLHAGTANNVIPSRARLELSVRSFDPEVRALLRRRITELAQAQAASYGASANVEYIEGYPVVVNSDAETDFAAQVAK
ELVGERNVVEQADILMGSEDFAFMLQRRPGSFVRLGNGAGEEGCMVHNPKYDFNDRNLVTGAAFWARLVERYLAR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=434, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787598, Length=214, Percent_Identity=30.8411214953271, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42536; Mature: 42536

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDARFTEVDDLAPLAEALREIRHRIHRHPELAYEEVETAALVADKLEAWGWRVTRGVGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCC
TGVVGTLRVGDGARSVGVRADMDALPIAEATGLPYASAVPGKMHACGHDGHTAMLLGAAW
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RLAQARHFSGTVHLYFQPAEEHGVDSGAKRMIDDGLFERFPCDAVFGMHNHPGVEPGVFL
HHHHHHCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEE
TRRGAFMSAGDKAVIDIHGVGGHAARPHLAVDPVVVAASVVMALQTIVARNVDPAQPAVV
EECCCEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TVGSLHAGTANNVIPSRARLELSVRSFDPEVRALLRRRITELAQAQAASYGASANVEYIE
EEECCCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
GYPVVVNSDAETDFAAQVAKELVGERNVVEQADILMGSEDFAFMLQRRPGSFVRLGNGAG
CCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHEECCCCCEEEECCCCC
EEGCMVHNPKYDFNDRNLVTGAAFWARLVERYLAR
CCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDARFTEVDDLAPLAEALREIRHRIHRHPELAYEEVETAALVADKLEAWGWRVTRGVGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCC
TGVVGTLRVGDGARSVGVRADMDALPIAEATGLPYASAVPGKMHACGHDGHTAMLLGAAW
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RLAQARHFSGTVHLYFQPAEEHGVDSGAKRMIDDGLFERFPCDAVFGMHNHPGVEPGVFL
HHHHHHCCCCEEEEEEECHHHCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEE
TRRGAFMSAGDKAVIDIHGVGGHAARPHLAVDPVVVAASVVMALQTIVARNVDPAQPAVV
EECCCEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TVGSLHAGTANNVIPSRARLELSVRSFDPEVRALLRRRITELAQAQAASYGASANVEYIE
EEECCCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
GYPVVVNSDAETDFAAQVAKELVGERNVVEQADILMGSEDFAFMLQRRPGSFVRLGNGAG
CCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHEECCCCCEEEECCCCC
EEGCMVHNPKYDFNDRNLVTGAAFWARLVERYLAR
CCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]