Click here to switch to the map view.

The map label for this gene is ucpA [H]

Identifier: 126446459

GI number: 126446459

Start: 1184297

End: 1185070

Strand: Direct

Name: ucpA [H]

Synonym: BMA10247_A1215

Alternate gene names: 126446459

Gene position: 1184297-1185070 (Clockwise)

Preceding gene: 126445935

Following gene: 126446759

Centisome position: 50.34

GC content: 71.06

Gene sequence:

>774_bases
ATGCGCATGACGACATCACGCACCACGCTGATCACGGGCGCCGCGGGCGGCATCGGCCAGGCGCTCGTGCGCGGCTTTCT
CGCCGCGGGCGACCGCGTGCTCGCGCTCGACCGCGACCGCGCGGCGCTCGCCGCGTTCGTCGACGCACTGGGCGACGCGG
CCGTCGCACCGATCATCGACGATCTGACCGACGCCGAACGCCTCGCGGCCGCGCTCGCGAACGAGCCTGTCGACGTGCTC
GTCGCGAACGCGGGCACGGCCGCGTCGGCGACGCTGCGCACGACGACGAGCGCATCGTGGCGCGCGGATCTCGACGCGAA
CCTGACCGCCACCTACGCGAGCGTCGAGGCCGTGCTCGCCGGCATGCGCGCGCGGCGACGCGGCGCGATCACGATCATCG
GCTCGGTCAACGGCGTCGCCGCGCTCGGGCACCCCGCCTACAGTGCGGCGAAGGCGGGACTCATCAGCTATGCGAAATCG
CTCGCCATCGAATACGGGCGCGACGGCGTGCGCGCGAACGTCGTGTGCCCCGGCACCGTGAAGACGCCCGCGTGGGAAGC
GCGCGTGCGGCAGAATCCGCAGGTGTTCGAGCAATTGAAGAAATGGTATCCGCTCGAGGATTTCGCGACGCCCGACGACG
TCGCGAACGCCGCCCTGTTCCTGTCGTCGGACGCCGCGCGCGCGATCACCGGCGCGATGCTGCCCGTCGACGGCGGGCTG
CTCGCGGGCAATCGCGTGATGGCGCAGGAGTTGACGCTCGAATCGTTTTATTGA

Upstream 100 bases:

>100_bases
CGCGCGAACGAAAAGACGGCGCGCGCGCAGCTCGGGCTGTGAAGCGCGCCGACGCCGCACGGCTGGCGGCGCCGGCGGCG
TTGGGTTTCGAACCGGAGGA

Downstream 100 bases:

>100_bases
CGCGCGGCGAACGATGCGCGCGTGCGCCGTCCACTCAATGCGCGGCCGAGCGCCGCGCGTGCGCCTCGCCCGCGCCCATC
CGCGCGAGCACGTGCTCGGT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MRMTTSRTTLITGAAGGIGQALVRGFLAAGDRVLALDRDRAALAAFVDALGDAAVAPIIDDLTDAERLAAALANEPVDVL
VANAGTAASATLRTTTSASWRADLDANLTATYASVEAVLAGMRARRRGAITIIGSVNGVAALGHPAYSAAKAGLISYAKS
LAIEYGRDGVRANVVCPGTVKTPAWEARVRQNPQVFEQLKKWYPLEDFATPDDVANAALFLSSDAARAITGAMLPVDGGL
LAGNRVMAQELTLESFY

Sequences:

>Translated_257_residues
MRMTTSRTTLITGAAGGIGQALVRGFLAAGDRVLALDRDRAALAAFVDALGDAAVAPIIDDLTDAERLAAALANEPVDVL
VANAGTAASATLRTTTSASWRADLDANLTATYASVEAVLAGMRARRRGAITIIGSVNGVAALGHPAYSAAKAGLISYAKS
LAIEYGRDGVRANVVCPGTVKTPAWEARVRQNPQVFEQLKKWYPLEDFATPDDVANAALFLSSDAARAITGAMLPVDGGL
LAGNRVMAQELTLESFY
>Mature_257_residues
MRMTTSRTTLITGAAGGIGQALVRGFLAAGDRVLALDRDRAALAAFVDALGDAAVAPIIDDLTDAERLAAALANEPVDVL
VANAGTAASATLRTTTSASWRADLDANLTATYASVEAVLAGMRARRRGAITIIGSVNGVAALGHPAYSAAKAGLISYAKS
LAIEYGRDGVRANVVCPGTVKTPAWEARVRQNPQVFEQLKKWYPLEDFATPDDVANAALFLSSDAARAITGAMLPVDGGL
LAGNRVMAQELTLESFY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=34.3096234309623, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=31.6, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI66933014, Length=223, Percent_Identity=30.0448430493274, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=29.4354838709677, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=32.4894514767932, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=27.1604938271605, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=28.1632653061224, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=29.9559471365639, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503301, Length=170, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI7657478, Length=195, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=25.5060728744939, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI31542939, Length=254, Percent_Identity=27.5590551181102, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=33.852140077821, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=34.0248962655602, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=32.2709163346614, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=29.718875502008, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=28.2786885245902, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=28.8065843621399, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787820, Length=236, Percent_Identity=30.5084745762712, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=22.9508196721311, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=26.0162601626016, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30.8, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=31.3008130081301, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=29.5081967213115, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=26.8199233716475, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.7575757575758, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=117, Percent_Identity=34.1880341880342, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=28.6259541984733, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=27.0676691729323, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=264, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=234, Percent_Identity=31.1965811965812, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=239, Percent_Identity=25.5230125523013, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=31.3807531380753, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644337, Length=222, Percent_Identity=29.7297297297297, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=31.3492063492063, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=28.3400809716599, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=30.6772908366534, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=28.4046692607004, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581726, Length=207, Percent_Identity=27.0531400966184, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=30.2083333333333, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI18859837, Length=186, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26662; Mature: 26662

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTTSRTTLITGAAGGIGQALVRGFLAAGDRVLALDRDRAALAAFVDALGDAAVAPIID
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHH
DLTDAERLAAALANEPVDVLVANAGTAASATLRTTTSASWRADLDANLTATYASVEAVLA
HHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHH
GMRARRRGAITIIGSVNGVAALGHPAYSAAKAGLISYAKSLAIEYGRDGVRANVVCPGTV
HHHHHCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
KTPAWEARVRQNPQVFEQLKKWYPLEDFATPDDVANAALFLSSDAARAITGAMLPVDGGL
CCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHEEEEECCCHHHHHHCCCCCCCCCE
LAGNRVMAQELTLESFY
EECCCHHHHHHHHHHCC
>Mature Secondary Structure
MRMTTSRTTLITGAAGGIGQALVRGFLAAGDRVLALDRDRAALAAFVDALGDAAVAPIID
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHH
DLTDAERLAAALANEPVDVLVANAGTAASATLRTTTSASWRADLDANLTATYASVEAVLA
HHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHH
GMRARRRGAITIIGSVNGVAALGHPAYSAAKAGLISYAKSLAIEYGRDGVRANVVCPGTV
HHHHHCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
KTPAWEARVRQNPQVFEQLKKWYPLEDFATPDDVANAALFLSSDAARAITGAMLPVDGGL
CCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHEEEEECCCHHHHHHCCCCCCCCCE
LAGNRVMAQELTLESFY
EECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]