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The map label for this gene is evgS [H]

Identifier: 126446255

GI number: 126446255

Start: 2195708

End: 2198023

Strand: Reverse

Name: evgS [H]

Synonym: BMA10247_A2264

Alternate gene names: 126446255

Gene position: 2198023-2195708 (Counterclockwise)

Preceding gene: 126446333

Following gene: 126447203

Centisome position: 93.43

GC content: 72.71

Gene sequence:

>2316_bases
ATGGCGAATTTTGTACGAGGACACGCAAAAAATTACGCGGCGGTGACGGGCTTCATCGCGATCGGTACGTTGCTGCAGGC
GGCGCTCGTGCGCTTCGGCGGCGCCGACATGCCGCTCGCGCCGTATTTTCCGTTCATCGCGGCGGCCGCCTGGGCGACGT
CGCTCGCGGGGGGGATCGCCGCGACCGCCGCGAGCGCGGCGCTCGCGTGGCTGCTGTTCCTGAACGATCCGGCCGCGTAT
TCGGCGCCGCTCGCGTGGCGGCTCATGCAGCTCGCGACGTTCGCCGTCGTGAGTTGCGCGATCTGCGCGATCGTCGTCGC
GCTCAAGGGCTCGCGCCGCGCGAACGACGCGTTGCGCCGCCGCGAGGCGGGGGCGCGCCACTACTACGAGACCCTGCTGC
AGTCGCTCACGCAGGGCGTCGTCGTCAGCGACCGGCACGGCATGCTCACGTACATGAACCCGAGCGCGGCCGCGCTGATC
GGCTGCGATGCGACGGCCGTGCGCGGTCTGCCGTTTCGCGACGTGTACCGCGCCTACGACGGGCGCGGCGCGCGCGTGCG
CGCGTCCGCGCTCGAGCACGTGCTGAGGAGCGGCAGGAGCGCGAGCGTCGAAGGGCACTGGCTTGCTCCGCACGACGGGC
AGCGGGTGCCGATCGCCGAAGCCGCGTCGCCGCTCGTCGATTCGGCGGGCGACATGACGGGCGCGGTGCTGATCGTGCGC
GACATCAGCATCGAGCGCGAGCGATCGGCGGCCAGCCAGATGCTGCGGCGGCTCGTCGAGGCCTCGCCCGACGCGATCGT
CGGGGTCGGCTCGAATCGCCGCATCACGAGCTGGAACCCGGCCGCGCGCCGGATGTTCGGCTACGACGAGCACGCGGCGC
GCGGGTGCGACGTCGCGATGCTGATCGCGCCGCGCTGGCTGCGCAATCATCCGCTGCCCGAATCGGTGCCCGACATGCGC
GAGCCGATCGAGAACGTCGACGTGCTGTGCGTGCGGCAGGACGGCGGGCGGATGCGCGCGACGATGTCGGCGTCGCCCGT
GTTCGACGAGCGCGACGCGTGCATCGCGCTGTCGCTGACGCTGCGCGACACGGGCGAGCAGCGCCGGCGCGAACGCCGCG
TGCACCGCTCGCTGCGCGGCGCGCGCGACGCGCGCCGGCAGGCCGACACGTCGAACCGGCTGAAGGACGAGCTGCTCGCC
ACCGTGTCGCACGAGCTGCGCACGCCGCTGAACGTGATCTACGGCTGGATCGAGGTGCTGCGCAATCCGGTGGACGGCGC
GCTGCAGCAGCAGGCGATCGATGCGATCGACCGCAGCGCGCGCTCGCTGTCGCGGATGGTCGGCGACATTCTCGATGCAT
CGTCGCTCGCGACGGGCAAGCTGCGGCTCGATGCGATGCCGGTCGATCTCGTGCGCATCGTCAACGACGTGACGGGCGCG
CTCGGCGCGGCCGCGCAGGCCGACGGGATCGCGCTGTCGGTCGAATGCGCGCTCGCCACGTGCATCGTGTCCGGCGACGG
CGAGCGGCTGCGGCAGATGCTGTCGAACCTGCTGTCGAACGCGTTCAAGTTCACGCCGCGCGGCGGCCGCGTGACCGTGT
CGCTCGAGCGCCACGACGCGCAGGCGAAGCTGACGGTCGCCGATACGGGCCATGGCATCTCGCCCGAATTCCTGCCGCAC
GTGTTCGAGGCGTTCCGGCGCGCGGAAGGCGCGCCCGCATCGCCGCGGCGCGGGCTCGGCCTCGGGCTGTCGATCGTGCG
GCACATCGCGGAGCTGCACGGCGGCAAGGTCGAGGCCGCGAGCGCGGGCAAGAACCGCGGCACGACGTTCGCGATCACGC
TGCCCGCCGGCTGGCAGCCGATGGGCGCGCTCGCATGGGCCGCGCAGGCCGAGGGCGGCGCGCGGATGACGCTCGACGCG
CAGCGGATCCTGCTCGTCGACGACGACGCGACCTCGCGTGCGAGCCTGGCCGCCGCGCTGAAGACGCTCGGCGCGGAGGT
GGTCGTCGCGTCGTCGGGGCGCGAGGCGATCGGGAAGGTGGACGCGATGCGGCCGACCGTCGTGCTGTCCGATCTCGCGA
TGCCCGACGGCGACGGCTACTGGCTGCTCGACACGCTGCGCCACGTGGACGCGGATGCGGATGCGGACACGCGCACGCGC
GCGGCGAACGACGCGCCGGTGCTCGCCGTCACCGCGCATGCGGGGCGCGACAGCGAGCGGCGCGTGCTCGCGGCGGGCTT
CGACGGCTATCTATGCAAGCCGGTCGATCTGCAGACGCTCGCGCGTGCGATCCTGCGCGCGACGGGCAGCGGCTGA

Upstream 100 bases:

>100_bases
TGCGCGGCTTGCCCGTGCGGAGCCGCAACTTCCGTGCCGCCGCGGCGCGTCCGGCTGCGCGCGCGCGCCGCGCGCCCACG
CGGCGGCAGGAGGGGATGTG

Downstream 100 bases:

>100_bases
CGCGCGCGGGTGAGCTCGCGAATCGCGAACCGTGTGGGTCTCGAGCATGGCCCCGAGCGCAGCGTACCGCGAGCTATGAG
GCATGAACCACGAACCACCC

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 770

Protein sequence:

>771_residues
MANFVRGHAKNYAAVTGFIAIGTLLQAALVRFGGADMPLAPYFPFIAAAAWATSLAGGIAATAASAALAWLLFLNDPAAY
SAPLAWRLMQLATFAVVSCAICAIVVALKGSRRANDALRRREAGARHYYETLLQSLTQGVVVSDRHGMLTYMNPSAAALI
GCDATAVRGLPFRDVYRAYDGRGARVRASALEHVLRSGRSASVEGHWLAPHDGQRVPIAEAASPLVDSAGDMTGAVLIVR
DISIERERSAASQMLRRLVEASPDAIVGVGSNRRITSWNPAARRMFGYDEHAARGCDVAMLIAPRWLRNHPLPESVPDMR
EPIENVDVLCVRQDGGRMRATMSASPVFDERDACIALSLTLRDTGEQRRRERRVHRSLRGARDARRQADTSNRLKDELLA
TVSHELRTPLNVIYGWIEVLRNPVDGALQQQAIDAIDRSARSLSRMVGDILDASSLATGKLRLDAMPVDLVRIVNDVTGA
LGAAAQADGIALSVECALATCIVSGDGERLRQMLSNLLSNAFKFTPRGGRVTVSLERHDAQAKLTVADTGHGISPEFLPH
VFEAFRRAEGAPASPRRGLGLGLSIVRHIAELHGGKVEAASAGKNRGTTFAITLPAGWQPMGALAWAAQAEGGARMTLDA
QRILLVDDDATSRASLAAALKTLGAEVVVASSGREAIGKVDAMRPTVVLSDLAMPDGDGYWLLDTLRHVDADADADTRTR
AANDAPVLAVTAHAGRDSERRVLAAGFDGYLCKPVDLQTLARAILRATGSG

Sequences:

>Translated_771_residues
MANFVRGHAKNYAAVTGFIAIGTLLQAALVRFGGADMPLAPYFPFIAAAAWATSLAGGIAATAASAALAWLLFLNDPAAY
SAPLAWRLMQLATFAVVSCAICAIVVALKGSRRANDALRRREAGARHYYETLLQSLTQGVVVSDRHGMLTYMNPSAAALI
GCDATAVRGLPFRDVYRAYDGRGARVRASALEHVLRSGRSASVEGHWLAPHDGQRVPIAEAASPLVDSAGDMTGAVLIVR
DISIERERSAASQMLRRLVEASPDAIVGVGSNRRITSWNPAARRMFGYDEHAARGCDVAMLIAPRWLRNHPLPESVPDMR
EPIENVDVLCVRQDGGRMRATMSASPVFDERDACIALSLTLRDTGEQRRRERRVHRSLRGARDARRQADTSNRLKDELLA
TVSHELRTPLNVIYGWIEVLRNPVDGALQQQAIDAIDRSARSLSRMVGDILDASSLATGKLRLDAMPVDLVRIVNDVTGA
LGAAAQADGIALSVECALATCIVSGDGERLRQMLSNLLSNAFKFTPRGGRVTVSLERHDAQAKLTVADTGHGISPEFLPH
VFEAFRRAEGAPASPRRGLGLGLSIVRHIAELHGGKVEAASAGKNRGTTFAITLPAGWQPMGALAWAAQAEGGARMTLDA
QRILLVDDDATSRASLAAALKTLGAEVVVASSGREAIGKVDAMRPTVVLSDLAMPDGDGYWLLDTLRHVDADADADTRTR
AANDAPVLAVTAHAGRDSERRVLAAGFDGYLCKPVDLQTLARAILRATGSG
>Mature_770_residues
ANFVRGHAKNYAAVTGFIAIGTLLQAALVRFGGADMPLAPYFPFIAAAAWATSLAGGIAATAASAALAWLLFLNDPAAYS
APLAWRLMQLATFAVVSCAICAIVVALKGSRRANDALRRREAGARHYYETLLQSLTQGVVVSDRHGMLTYMNPSAAALIG
CDATAVRGLPFRDVYRAYDGRGARVRASALEHVLRSGRSASVEGHWLAPHDGQRVPIAEAASPLVDSAGDMTGAVLIVRD
ISIERERSAASQMLRRLVEASPDAIVGVGSNRRITSWNPAARRMFGYDEHAARGCDVAMLIAPRWLRNHPLPESVPDMRE
PIENVDVLCVRQDGGRMRATMSASPVFDERDACIALSLTLRDTGEQRRRERRVHRSLRGARDARRQADTSNRLKDELLAT
VSHELRTPLNVIYGWIEVLRNPVDGALQQQAIDAIDRSARSLSRMVGDILDASSLATGKLRLDAMPVDLVRIVNDVTGAL
GAAAQADGIALSVECALATCIVSGDGERLRQMLSNLLSNAFKFTPRGGRVTVSLERHDAQAKLTVADTGHGISPEFLPHV
FEAFRRAEGAPASPRRGLGLGLSIVRHIAELHGGKVEAASAGKNRGTTFAITLPAGWQPMGALAWAAQAEGGARMTLDAQ
RILLVDDDATSRASLAAALKTLGAEVVVASSGREAIGKVDAMRPTVVLSDLAMPDGDGYWLLDTLRHVDADADADTRTRA
ANDAPVLAVTAHAGRDSERRVLAAGFDGYLCKPVDLQTLARAILRATGSG

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=375, Percent_Identity=31.7333333333333, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI48994928, Length=566, Percent_Identity=27.5618374558304, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1789149, Length=295, Percent_Identity=29.8305084745763, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI87081816, Length=392, Percent_Identity=29.8469387755102, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI1786600, Length=296, Percent_Identity=30.7432432432432, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=30.8370044052863, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=32.7272727272727, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788549, Length=371, Percent_Identity=24.2587601078167, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=28.4552845528455, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=30.0813008130081, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=31.0810810810811, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=28.0701754385965, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=225, Percent_Identity=29.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790551, Length=211, Percent_Identity=28.9099526066351, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=27.1493212669683, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=210, Percent_Identity=29.5238095238095, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=29.5566502463054, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=27.4678111587983, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82290; Mature: 82159

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFVRGHAKNYAAVTGFIAIGTLLQAALVRFGGADMPLAPYFPFIAAAAWATSLAGGIA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATAASAALAWLLFLNDPAAYSAPLAWRLMQLATFAVVSCAICAIVVALKGSRRANDALRR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
REAGARHYYETLLQSLTQGVVVSDRHGMLTYMNPSAAALIGCDATAVRGLPFRDVYRAYD
HHCCHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCEEEEECCHHHHCCCCHHHHHHHHC
GRGARVRASALEHVLRSGRSASVEGHWLAPHDGQRVPIAEAASPLVDSAGDMTGAVLIVR
CCCCEEHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEE
DISIERERSAASQMLRRLVEASPDAIVGVGSNRRITSWNPAARRMFGYDEHAARGCDVAM
ECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCHHHHHHCCCCHHHCCCCCEEE
LIAPRWLRNHPLPESVPDMREPIENVDVLCVRQDGGRMRATMSASPVFDERDACIALSLT
EECCHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEE
LRDTGEQRRRERRVHRSLRGARDARRQADTSNRLKDELLATVSHELRTPLNVIYGWIEVL
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RNPVDGALQQQAIDAIDRSARSLSRMVGDILDASSLATGKLRLDAMPVDLVRIVNDVTGA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHH
LGAAAQADGIALSVECALATCIVSGDGERLRQMLSNLLSNAFKFTPRGGRVTVSLERHDA
HCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCC
QAKLTVADTGHGISPEFLPHVFEAFRRAEGAPASPRRGLGLGLSIVRHIAELHGGKVEAA
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEC
SAGKNRGTTFAITLPAGWQPMGALAWAAQAEGGARMTLDAQRILLVDDDATSRASLAAAL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHH
KTLGAEVVVASSGREAIGKVDAMRPTVVLSDLAMPDGDGYWLLDTLRHVDADADADTRTR
HHCCCEEEEECCCCHHHHHHHCCCCHHEEHHHCCCCCCCEEHHHHHHHCCCCCCCCCHHC
AANDAPVLAVTAHAGRDSERRVLAAGFDGYLCKPVDLQTLARAILRATGSG
CCCCCCEEEEEECCCCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANFVRGHAKNYAAVTGFIAIGTLLQAALVRFGGADMPLAPYFPFIAAAAWATSLAGGIA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATAASAALAWLLFLNDPAAYSAPLAWRLMQLATFAVVSCAICAIVVALKGSRRANDALRR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
REAGARHYYETLLQSLTQGVVVSDRHGMLTYMNPSAAALIGCDATAVRGLPFRDVYRAYD
HHCCHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCEEEEECCHHHHCCCCHHHHHHHHC
GRGARVRASALEHVLRSGRSASVEGHWLAPHDGQRVPIAEAASPLVDSAGDMTGAVLIVR
CCCCEEHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEE
DISIERERSAASQMLRRLVEASPDAIVGVGSNRRITSWNPAARRMFGYDEHAARGCDVAM
ECCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCHHHHHHCCCCHHHCCCCCEEE
LIAPRWLRNHPLPESVPDMREPIENVDVLCVRQDGGRMRATMSASPVFDERDACIALSLT
EECCHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEE
LRDTGEQRRRERRVHRSLRGARDARRQADTSNRLKDELLATVSHELRTPLNVIYGWIEVL
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RNPVDGALQQQAIDAIDRSARSLSRMVGDILDASSLATGKLRLDAMPVDLVRIVNDVTGA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHH
LGAAAQADGIALSVECALATCIVSGDGERLRQMLSNLLSNAFKFTPRGGRVTVSLERHDA
HCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCC
QAKLTVADTGHGISPEFLPHVFEAFRRAEGAPASPRRGLGLGLSIVRHIAELHGGKVEAA
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEC
SAGKNRGTTFAITLPAGWQPMGALAWAAQAEGGARMTLDAQRILLVDDDATSRASLAAAL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCEEEEEECCCCHHHHHHHHH
KTLGAEVVVASSGREAIGKVDAMRPTVVLSDLAMPDGDGYWLLDTLRHVDADADADTRTR
HHCCCEEEEECCCCHHHHHHHCCCCHHEEHHHCCCCCCCEEHHHHHHHCCCCCCCCCHHC
AANDAPVLAVTAHAGRDSERRVLAAGFDGYLCKPVDLQTLARAILRATGSG
CCCCCCEEEEEECCCCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]