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The map label for this gene is lrp [H]

Identifier: 126445710

GI number: 126445710

Start: 938567

End: 939049

Strand: Reverse

Name: lrp [H]

Synonym: BMA10247_A0991

Alternate gene names: 126445710

Gene position: 939049-938567 (Counterclockwise)

Preceding gene: 126445916

Following gene: 126447370

Centisome position: 39.91

GC content: 61.08

Gene sequence:

>483_bases
ATGAAGCTCGACGAAACAGATCTGAAGATTCTGAAGATCCTGCAGGAGAACGGGCGCCTCAGCAACGCGGAACTGGCCGA
TCGCGTCGCACTGTCGGCGGCGCCGTGCTGGAAGCGCCTGCGCCGGCTCGAGGCCGACGGCTTCATCTCGGGCTATCAGG
CGATTCTCGACCGGCGCGCGCTCGGCTACGAGATCGTCGCGTTCGTCAACATTTCGCTCGACAGTCACACCGAGAAGACC
TGCCGCGCATTCGAAGCGGGCGTGATGGCGATGCCGGAAGTGGTCGCGTGCCACAACACGACCGGCCAGCACGACTATCT
CGTGCAAATCGTCGCGAAGAATTTCGATACGTTCTCGAGCTTCGTGTTGAATCGGCTTCGGTCGCTGCCCGGCGTGAAGG
AGCTGCTCAGCACGATCTCGATGCGCGAACTGAAAGCGACGAGCCGGCTGCCTGCCGGAGAATTGAGGATCACGAAACAA
TGA

Upstream 100 bases:

>100_bases
AGAAAGCTAGCAGGAAATATGCTTTCCATTTCATTCCGGCGCCCCCCTATAATCGAAAGAATCTTTCCGCTTTCATTCCT
TCCATAAAAAGGCGATCGGC

Downstream 100 bases:

>100_bases
CGCCGATTGCGAACGCCGAATCGGCGCGAATCGTTCTGCGCCGCAAAATGAATGCCCGCCATTGCGGCTCGATGCGCGCA
CGCAGCATGGCGGCCGCGAC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKLDETDLKILKILQENGRLSNAELADRVALSAAPCWKRLRRLEADGFISGYQAILDRRALGYEIVAFVNISLDSHTEKT
CRAFEAGVMAMPEVVACHNTTGQHDYLVQIVAKNFDTFSSFVLNRLRSLPGVKELLSTISMRELKATSRLPAGELRITKQ

Sequences:

>Translated_160_residues
MKLDETDLKILKILQENGRLSNAELADRVALSAAPCWKRLRRLEADGFISGYQAILDRRALGYEIVAFVNISLDSHTEKT
CRAFEAGVMAMPEVVACHNTTGQHDYLVQIVAKNFDTFSSFVLNRLRSLPGVKELLSTISMRELKATSRLPAGELRITKQ
>Mature_160_residues
MKLDETDLKILKILQENGRLSNAELADRVALSAAPCWKRLRRLEADGFISGYQAILDRRALGYEIVAFVNISLDSHTEKT
CRAFEAGVMAMPEVVACHNTTGQHDYLVQIVAKNFDTFSSFVLNRLRSLPGVKELLSTISMRELKATSRLPAGELRITKQ

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=148, Percent_Identity=37.1621621621622, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=38, Blast_Score=109, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17909; Mature: 17909

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDETDLKILKILQENGRLSNAELADRVALSAAPCWKRLRRLEADGFISGYQAILDRRA
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LGYEIVAFVNISLDSHTEKTCRAFEAGVMAMPEVVACHNTTGQHDYLVQIVAKNFDTFSS
CCEEEEEEEEECCCCCHHHHHHHHHHCHHHCCHHHHHCCCCCCHHHHHHHHHHCCHHHHH
FVLNRLRSLPGVKELLSTISMRELKATSRLPAGELRITKQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MKLDETDLKILKILQENGRLSNAELADRVALSAAPCWKRLRRLEADGFISGYQAILDRRA
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LGYEIVAFVNISLDSHTEKTCRAFEAGVMAMPEVVACHNTTGQHDYLVQIVAKNFDTFSS
CCEEEEEEEEECCCCCHHHHHHHHHHCHHHCCHHHHHCCCCCCHHHHHHHHHHCCHHHHH
FVLNRLRSLPGVKELLSTISMRELKATSRLPAGELRITKQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]