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The map label for this gene is lolA

Identifier: 126207958

GI number: 126207958

Start: 546848

End: 547489

Strand: Direct

Name: lolA

Synonym: APL_0474

Alternate gene names: 126207958

Gene position: 546848-547489 (Clockwise)

Preceding gene: 126207957

Following gene: 126207959

Centisome position: 24.04

GC content: 40.34

Gene sequence:

>642_bases
ATGAAAAAATTACTTAAGCAATCATTATTAGGTTTTGCCTTAGTTTCTATGACTGGCGCAGCTTTTGCCGATGCGCAGTC
AGTTGCCGAATTACAACGACGTTTAGAGCAAGTCAGCCAATATAGTGCGGATTTTGATCAAACGGTGCGTTCAAGCAAAG
GTAAACAAATTCAATCGGGTAAAGGTAAATTCCAAGTAAAACGCCCGAATTTGTTCCGTATGGATACTAAATCGCCACAG
GAAAATTTAATTGTTTCGGACGGTGCGAATTTATGGTTTTACGACCCGTTTGTTTCACAAGTGACGGTGAATACGGTGCA
AGATGCGGTAAATAATACTCCGTTCGTGTTATTAACCAGTAGCGATAAAAGCCACTGGGATCAATATGATGTGACGCAAA
ACGCGGATACATTCGTATTAAAACCGAAATCGAAAAAAAGTAATTTAAAACAGTTTGATGTGCGAATTGATCAAAGCGGT
ATGTTAAAAGGTTTCAGCACCATTGAACGAGACGGTCAGAGCAATTTATACGTATTACGCAATATTACCGGTGGCGGTGT
ATCGTCCGACTTGTTCAAATTTAGCGTACCGAAAGGTGCCGAGTTAGACGACCAACGCGGCGGTAAAAAATCTAAGAAAT
AA

Upstream 100 bases:

>100_bases
TTATTTTATTGTATCGTTATGCTAGTACGAGCTTTGTGAAACTTTTACAGAATAGGTTGTCAAAGAGGCACTTGATTCTC
TTTGATAGAAGGAACAAAAA

Downstream 100 bases:

>100_bases
TCTAATTTTACTAGCGGTTTTATTTTCGCAAAATTTTGCCAAAATCAGACCGCTTTCCTTATTTTGGAGGTTCAATGAAA
ATTCTTTATAATCAACGAGA

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKKLLKQSLLGFALVSMTGAAFADAQSVAELQRRLEQVSQYSADFDQTVRSSKGKQIQSGKGKFQVKRPNLFRMDTKSPQ
ENLIVSDGANLWFYDPFVSQVTVNTVQDAVNNTPFVLLTSSDKSHWDQYDVTQNADTFVLKPKSKKSNLKQFDVRIDQSG
MLKGFSTIERDGQSNLYVLRNITGGGVSSDLFKFSVPKGAELDDQRGGKKSKK

Sequences:

>Translated_213_residues
MKKLLKQSLLGFALVSMTGAAFADAQSVAELQRRLEQVSQYSADFDQTVRSSKGKQIQSGKGKFQVKRPNLFRMDTKSPQ
ENLIVSDGANLWFYDPFVSQVTVNTVQDAVNNTPFVLLTSSDKSHWDQYDVTQNADTFVLKPKSKKSNLKQFDVRIDQSG
MLKGFSTIERDGQSNLYVLRNITGGGVSSDLFKFSVPKGAELDDQRGGKKSKK
>Mature_213_residues
MKKLLKQSLLGFALVSMTGAAFADAQSVAELQRRLEQVSQYSADFDQTVRSSKGKQIQSGKGKFQVKRPNLFRMDTKSPQ
ENLIVSDGANLWFYDPFVSQVTVNTVQDAVNNTPFVLLTSSDKSHWDQYDVTQNADTFVLKPKSKKSNLKQFDVRIDQSG
MLKGFSTIERDGQSNLYVLRNITGGGVSSDLFKFSVPKGAELDDQRGGKKSKK

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=202, Percent_Identity=41.0891089108911, Blast_Score=173, Evalue=8e-45,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_ACTP2 (A3MZJ2)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001053183.1
- ProteinModelPortal:   A3MZJ2
- SMR:   A3MZJ2
- STRING:   A3MZJ2
- GeneID:   4849737
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0474
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   YSADFEQ
- PhylomeDB:   A3MZJ2
- ProtClustDB:   PRK00031
- BioCyc:   APLE416269:APL_0474-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23729; Mature: 23729

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLKQSLLGFALVSMTGAAFADAQSVAELQRRLEQVSQYSADFDQTVRSSKGKQIQSG
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCC
KGKFQVKRPNLFRMDTKSPQENLIVSDGANLWFYDPFVSQVTVNTVQDAVNNTPFVLLTS
CCEEEEECCCEEEECCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEC
SDKSHWDQYDVTQNADTFVLKPKSKKSNLKQFDVRIDQSGMLKGFSTIERDGQSNLYVLR
CCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEE
NITGGGVSSDLFKFSVPKGAELDDQRGGKKSKK
ECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKLLKQSLLGFALVSMTGAAFADAQSVAELQRRLEQVSQYSADFDQTVRSSKGKQIQSG
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCC
KGKFQVKRPNLFRMDTKSPQENLIVSDGANLWFYDPFVSQVTVNTVQDAVNNTPFVLLTS
CCEEEEECCCEEEECCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEC
SDKSHWDQYDVTQNADTFVLKPKSKKSNLKQFDVRIDQSGMLKGFSTIERDGQSNLYVLR
CCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEE
NITGGGVSSDLFKFSVPKGAELDDQRGGKKSKK
ECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA