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The map label for this gene is fruK [H]

Identifier: 126207828

GI number: 126207828

Start: 380652

End: 381599

Strand: Reverse

Name: fruK [H]

Synonym: APL_0344

Alternate gene names: 126207828

Gene position: 381599-380652 (Counterclockwise)

Preceding gene: 126207829

Following gene: 126207827

Centisome position: 16.78

GC content: 47.78

Gene sequence:

>948_bases
ATGACACAACAATTACGAATTGCAACCGTTACCTTAAATCCAGCGTTTGACTTGGTCGGCCGCCTACAACGTATTGAAGT
GGGCGAAGTAAACACGGTTGAAACCTTAGGTTTATATCCTGCCGGTAAGGGCATCAACGTTGCGAAAGTATTGGCGGATC
TCGGCGTTAAATTAGCGGTTAGCGGTTTTTTAGGCGCTGAAAATCAAGGCGATTTCGTTCAATCGTTTAAACAAAACGGT
GTGGACGATCAATTCTATCGTATTGACGGTAAAACGCGTATTAACGTGAAAATTACCGAAACCGAAGCGGACGTGACCGA
CTTGAACTTCTTAGGTTTTGAAATTAGCGCCGAAGATTGGACGAACTTTACCGCTCAATCACAGCAATGGGCAAAAGCGT
TTGATTTGGTGGCGGTATGCGGTTCGCTCCCTCGCGGTGTAACGGCACAACAATTTGCACAATGGTTGGAATCGCTCCAT
CAACAAGGTTTAAAAGTCGTATTAGACAGCAGCAATGCGGCATTAACCGAAGGCTTAAAAGCACACCCGTGGTTAGTAAA
ACCGAATCGCCGTGAGTTAGAAGTTTGGGCGAATCGTCCGTTAAACAGCTTAGAAGAAGTGATTGCGGCGGCACAAGAAT
TGCGTGCCGGCGGTATTGAGAACGTGATTATTTCAATGGGCGCAGACGGTTCCGTATGGCTCAACAGCGAAGGCGTGGTT
CAAGCTCAACCGCCTCGTTGCCAAAATGTTGTGAGTACGGTCGGTGCCGGCGATTCGATGGTGGCAGGCTTAATTTATGG
GCTTGCTCAAGGTTGGGATAAAGCGAAAACTCTCGCCTTCGCAAGCGGTACATCGGCATTAGCGGTATCACAAAGCAATG
TCGGTATCAGCGACCGAAACGCCCTAGATGAGATTGTGGCGCAGGTGAAATTAACCCGATTAAGCTAA

Upstream 100 bases:

>100_bases
GCTTACATTTCGTAGCAACCGGTGACGACGCTCAAAAAGCGATTGACGGTATCGGCGAGGCAATTGCGGCAGGCTTAGGC
GAGTAATTGAGGAACAGACA

Downstream 100 bases:

>100_bases
TAATTTGTCATCAAATCTCCCCCTACCCCTCTTTACTAAAGAGGGGGGAATAAATTTTCTCAAACTTATAAGGATCTCAA
AATGAATATTTCCTTTGTAT

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTQQLRIATVTLNPAFDLVGRLQRIEVGEVNTVETLGLYPAGKGINVAKVLADLGVKLAVSGFLGAENQGDFVQSFKQNG
VDDQFYRIDGKTRINVKITETEADVTDLNFLGFEISAEDWTNFTAQSQQWAKAFDLVAVCGSLPRGVTAQQFAQWLESLH
QQGLKVVLDSSNAALTEGLKAHPWLVKPNRRELEVWANRPLNSLEEVIAAAQELRAGGIENVIISMGADGSVWLNSEGVV
QAQPPRCQNVVSTVGAGDSMVAGLIYGLAQGWDKAKTLAFASGTSALAVSQSNVGISDRNALDEIVAQVKLTRLS

Sequences:

>Translated_315_residues
MTQQLRIATVTLNPAFDLVGRLQRIEVGEVNTVETLGLYPAGKGINVAKVLADLGVKLAVSGFLGAENQGDFVQSFKQNG
VDDQFYRIDGKTRINVKITETEADVTDLNFLGFEISAEDWTNFTAQSQQWAKAFDLVAVCGSLPRGVTAQQFAQWLESLH
QQGLKVVLDSSNAALTEGLKAHPWLVKPNRRELEVWANRPLNSLEEVIAAAQELRAGGIENVIISMGADGSVWLNSEGVV
QAQPPRCQNVVSTVGAGDSMVAGLIYGLAQGWDKAKTLAFASGTSALAVSQSNVGISDRNALDEIVAQVKLTRLS
>Mature_314_residues
TQQLRIATVTLNPAFDLVGRLQRIEVGEVNTVETLGLYPAGKGINVAKVLADLGVKLAVSGFLGAENQGDFVQSFKQNGV
DDQFYRIDGKTRINVKITETEADVTDLNFLGFEISAEDWTNFTAQSQQWAKAFDLVAVCGSLPRGVTAQQFAQWLESLHQ
QGLKVVLDSSNAALTEGLKAHPWLVKPNRRELEVWANRPLNSLEEVIAAAQELRAGGIENVIISMGADGSVWLNSEGVVQ
AQPPRCQNVVSTVGAGDSMVAGLIYGLAQGWDKAKTLAFASGTSALAVSQSNVGISDRNALDEIVAQVKLTRLS

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=306, Percent_Identity=54.5751633986928, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1788017, Length=289, Percent_Identity=30.4498269896194, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788491, Length=105, Percent_Identity=34.2857142857143, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 33838; Mature: 33706

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQLRIATVTLNPAFDLVGRLQRIEVGEVNTVETLGLYPAGKGINVAKVLADLGVKLAV
CCCCEEEEEEEECHHHHHHHHHHHEECCCCCCCCEEECCCCCCCCHHHHHHHHCCHHEEE
SGFLGAENQGDFVQSFKQNGVDDQFYRIDGKTRINVKITETEADVTDLNFLGFEISAEDW
EHHCCCCCCCHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCCCCCEEEEEEEEEEHHHH
TNFTAQSQQWAKAFDLVAVCGSLPRGVTAQQFAQWLESLHQQGLKVVLDSSNAALTEGLK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCC
AHPWLVKPNRRELEVWANRPLNSLEEVIAAAQELRAGGIENVIISMGADGSVWLNSEGVV
CCCEEECCCCCEEHEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCEE
QAQPPRCQNVVSTVGAGDSMVAGLIYGLAQGWDKAKTLAFASGTSALAVSQSNVGISDRN
EECCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCEEEEECCCCCCCCHH
ALDEIVAQVKLTRLS
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQQLRIATVTLNPAFDLVGRLQRIEVGEVNTVETLGLYPAGKGINVAKVLADLGVKLAV
CCCEEEEEEEECHHHHHHHHHHHEECCCCCCCCEEECCCCCCCCHHHHHHHHCCHHEEE
SGFLGAENQGDFVQSFKQNGVDDQFYRIDGKTRINVKITETEADVTDLNFLGFEISAEDW
EHHCCCCCCCHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCCCCCEEEEEEEEEEHHHH
TNFTAQSQQWAKAFDLVAVCGSLPRGVTAQQFAQWLESLHQQGLKVVLDSSNAALTEGLK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCC
AHPWLVKPNRRELEVWANRPLNSLEEVIAAAQELRAGGIENVIISMGADGSVWLNSEGVV
CCCEEECCCCCEEHEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCEE
QAQPPRCQNVVSTVGAGDSMVAGLIYGLAQGWDKAKTLAFASGTSALAVSQSNVGISDRN
EECCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHEEEEECCCCEEEEECCCCCCCCHH
ALDEIVAQVKLTRLS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]