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The map label for this gene is potC [H]

Identifier: 126207770

GI number: 126207770

Start: 312153

End: 312893

Strand: Direct

Name: potC [H]

Synonym: APL_0282

Alternate gene names: 126207770

Gene position: 312153-312893 (Clockwise)

Preceding gene: 126207769

Following gene: 126207771

Centisome position: 13.72

GC content: 38.19

Gene sequence:

>741_bases
ATGTTCGTGGTGTTTGCCTACCTTTATATTCCGATTATTATTTTGGTGGTAAACTCATTTAACGAAGACCGTTACGGCTT
ACAATGGAAAGGATTCAGTTGGAACTGGTATGAGCGTTTATTCGCTAATGATACGTTAGTGCAAGCGACGATGAACTCAT
TAACGATTGCATTTTTTGCCGCAACGTTTTCAACTGTTTTAGGGGCATTAACTTCGATTGCGCTATACCGCTATAAATTC
CGTGGTATGCAAATGGTCGGTGGTTTACTGTTTATCGTCATGATGTCACCGGATATCGTAATGGCCGTTTCATTATTAGT
ATTATTTATGATTTTAGGTGTGCGACTTGGCTTTATTTCGTTATTAATTGCGCATATTACTTTCTGTTTGCCTTATGTGG
TCATTACTATTTCATCTCGTTTAAGCGATTTTGACGGTAAGATGTTGGAAGCGGCAAAAGATTTAGGTGCAAGCGAAGTA
ACGATTTTACGTAAAATTATTTTACCGTTGGCATTACCGTCGATTATTTCCGGTTGGTTATTAAGCTTTACCATTTCGTT
GGATGACGTAGTGGTTTCATCATTCGTTACCAGCCCAAGTTATGAAGTATTACCGTTAAAAATCTTCTCGCTGGTGAAAA
CGGGTGTAACGCCGGAAGTCAATGCGTTAGCAACGATTATGATTATTTTCTCACTGACATTAGTGGTCTTAAGCCAATTA
GTGGTAAGAAAAAAAGCATAA

Upstream 100 bases:

>100_bases
TGTTAATGGCGTTAATGTTATATGTTTATTACCGTGCAAATAAATTATTAAATAAAAAGGTGGAGCTTGAATAATGAAAA
AGACCTTAAGAAACTTTTTT

Downstream 100 bases:

>100_bases
TTTAATTTGATTAAACATAGCTCGCTGATTAGCGGGCTATTTTTTTGCAAAAAATTAGCTGAAATAGACCGCTTGTTAGC
CTGTTATTCTATACAGTTTT

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MFVVFAYLYIPIIILVVNSFNEDRYGLQWKGFSWNWYERLFANDTLVQATMNSLTIAFFAATFSTVLGALTSIALYRYKF
RGMQMVGGLLFIVMMSPDIVMAVSLLVLFMILGVRLGFISLLIAHITFCLPYVVITISSRLSDFDGKMLEAAKDLGASEV
TILRKIILPLALPSIISGWLLSFTISLDDVVVSSFVTSPSYEVLPLKIFSLVKTGVTPEVNALATIMIIFSLTLVVLSQL
VVRKKA

Sequences:

>Translated_246_residues
MFVVFAYLYIPIIILVVNSFNEDRYGLQWKGFSWNWYERLFANDTLVQATMNSLTIAFFAATFSTVLGALTSIALYRYKF
RGMQMVGGLLFIVMMSPDIVMAVSLLVLFMILGVRLGFISLLIAHITFCLPYVVITISSRLSDFDGKMLEAAKDLGASEV
TILRKIILPLALPSIISGWLLSFTISLDDVVVSSFVTSPSYEVLPLKIFSLVKTGVTPEVNALATIMIIFSLTLVVLSQL
VVRKKA
>Mature_246_residues
MFVVFAYLYIPIIILVVNSFNEDRYGLQWKGFSWNWYERLFANDTLVQATMNSLTIAFFAATFSTVLGALTSIALYRYKF
RGMQMVGGLLFIVMMSPDIVMAVSLLVLFMILGVRLGFISLLIAHITFCLPYVVITISSRLSDFDGKMLEAAKDLGASEV
TILRKIILPLALPSIISGWLLSFTISLDDVVVSSFVTSPSYEVLPLKIFSLVKTGVTPEVNALATIMIIFSLTLVVLSQL
VVRKKA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=245, Percent_Identity=67.3469387755102, Blast_Score=332, Evalue=1e-92,
Organism=Escherichia coli, GI1787081, Length=231, Percent_Identity=41.991341991342, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787714, Length=242, Percent_Identity=25.6198347107438, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788764, Length=216, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27334; Mature: 27334

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCC
>Mature Secondary Structure
MFVVFAYLYIPIIILVVNSFNEDRYGLQWKGFSWNWYERLFANDTLVQATMNSLTIAFFA
CHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
ATFSTVLGALTSIALYRYKFRGMQMVGGLLFIVMMSPDIVMAVSLLVLFMILGVRLGFIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LLIAHITFCLPYVVITISSRLSDFDGKMLEAAKDLGASEVTILRKIILPLALPSIISGWL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LSFTISLDDVVVSSFVTSPSYEVLPLKIFSLVKTGVTPEVNALATIMIIFSLTLVVLSQL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VVRKKA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]