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The map label for this gene is gpmB [H]

Identifier: 126207718

GI number: 126207718

Start: 249991

End: 250623

Strand: Direct

Name: gpmB [H]

Synonym: APL_0230

Alternate gene names: 126207718

Gene position: 249991-250623 (Clockwise)

Preceding gene: 126207715

Following gene: 126207723

Centisome position: 10.99

GC content: 41.86

Gene sequence:

>633_bases
ATGGCACTCAACATTTATTTAGTCCGCCACGGGAAAACCGTCTGGAATTTGGAAGGGCGTTTGCAAGGCTCCGGCGATTC
ACCTTTGGTTGAAGAAGGTATTGAAGGGGCAAAAAAAGTGGGGAGAGCGTTAAAAGCGGTTAAATTTGCCGCCGCTTATT
CCAGTATGCAAAAACGAGCGCAAGATACCGCAAATTATATTTTGGCGGAAAATAATGATAAGAACATTCCGCACTTTCAC
CACTTCGGTTTGAACGAGTTCGATTTTGGGCTTTGGGAAGGTACGAAATCGGTAGATTTATACTCAAATGATGAATATTG
GACGATGAAAAAAACACCGGCGGAATATCGTGCGGAAACGAATGGCGGTGAAACTTATGAAGATCTTTATAGCCGTGTGA
TTAAAGTGTTTAATCAAATTGCACAGTTACATCAAGATAATGAAAACATATTAATTGTTGCACATGGTATGACATTAACT
GTTCTCACAGCGGTATTACGAGGCTTGCATTGGTCGGAATGTCGTGACGAAACTAAACACAGTTTTGTGATTAACACCGC
GATAAACCGAGCGGTTGTAGAGAAGGGTAAGGCTGAATTAGTTGAGTTTAACCGCACGGAACATTTGGCTTAG

Upstream 100 bases:

>100_bases
AATCACAACAAAGTCGTGATGTTGGAAGCAAATAGTCAATTTTTCAGTCATTTTTTGCTATACTCCGATAAATTTTGTCT
ATTTTAACAGGGAATTGAAT

Downstream 100 bases:

>100_bases
ATTTGCAAAAAATCCAAAAATTAGACCGCTTATTTGCGTTGTTCAAATTAGCGGTCTTATTCTTTTTTATTGGGCTTCAA
ACCAGCTTTCTAAAATTAAA

Product: phosphoglycerate mutase/fructose-2, 6-bisphosphatase

Products: NA

Alternate protein names: BPG-dependent PGAM 2; PGAM 2; Phosphoglyceromutase 2; dPGM 2 [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MALNIYLVRHGKTVWNLEGRLQGSGDSPLVEEGIEGAKKVGRALKAVKFAAAYSSMQKRAQDTANYILAENNDKNIPHFH
HFGLNEFDFGLWEGTKSVDLYSNDEYWTMKKTPAEYRAETNGGETYEDLYSRVIKVFNQIAQLHQDNENILIVAHGMTLT
VLTAVLRGLHWSECRDETKHSFVINTAINRAVVEKGKAELVEFNRTEHLA

Sequences:

>Translated_210_residues
MALNIYLVRHGKTVWNLEGRLQGSGDSPLVEEGIEGAKKVGRALKAVKFAAAYSSMQKRAQDTANYILAENNDKNIPHFH
HFGLNEFDFGLWEGTKSVDLYSNDEYWTMKKTPAEYRAETNGGETYEDLYSRVIKVFNQIAQLHQDNENILIVAHGMTLT
VLTAVLRGLHWSECRDETKHSFVINTAINRAVVEKGKAELVEFNRTEHLA
>Mature_209_residues
ALNIYLVRHGKTVWNLEGRLQGSGDSPLVEEGIEGAKKVGRALKAVKFAAAYSSMQKRAQDTANYILAENNDKNIPHFHH
FGLNEFDFGLWEGTKSVDLYSNDEYWTMKKTPAEYRAETNGGETYEDLYSRVIKVFNQIAQLHQDNENILIVAHGMTLTV
LTAVLRGLHWSECRDETKHSFVINTAINRAVVEKGKAELVEFNRTEHLA

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=168, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1790856, Length=174, Percent_Identity=31.6091954022989, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324857, Length=191, Percent_Identity=25.6544502617801, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 23798; Mature: 23667

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNIYLVRHGKTVWNLEGRLQGSGDSPLVEEGIEGAKKVGRALKAVKFAAAYSSMQKRA
CEEEEEEEECCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDTANYILAENNDKNIPHFHHFGLNEFDFGLWEGTKSVDLYSNDEYWTMKKTPAEYRAET
HHHHCEEEECCCCCCCCCEEECCCCCCCCHHCCCCCCEEEECCCCEEEEECCCHHHHCCC
NGGETYEDLYSRVIKVFNQIAQLHQDNENILIVAHGMTLTVLTAVLRGLHWSECRDETKH
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHH
SFVINTAINRAVVEKGKAELVEFNRTEHLA
EEEEHHHHHHHHHHCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
ALNIYLVRHGKTVWNLEGRLQGSGDSPLVEEGIEGAKKVGRALKAVKFAAAYSSMQKRA
EEEEEEEECCCEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDTANYILAENNDKNIPHFHHFGLNEFDFGLWEGTKSVDLYSNDEYWTMKKTPAEYRAET
HHHHCEEEECCCCCCCCCEEECCCCCCCCHHCCCCCCEEEECCCCEEEEECCCHHHHCCC
NGGETYEDLYSRVIKVFNQIAQLHQDNENILIVAHGMTLTVLTAVLRGLHWSECRDETKH
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHH
SFVINTAINRAVVEKGKAELVEFNRTEHLA
EEEEHHHHHHHHHHCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]