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The map label for this gene is infC [H]

Identifier: 126207711

GI number: 126207711

Start: 245638

End: 246117

Strand: Direct

Name: infC [H]

Synonym: APL_0223

Alternate gene names: 126207711

Gene position: 245638-246117 (Clockwise)

Preceding gene: 126207710

Following gene: 126207712

Centisome position: 10.8

GC content: 41.88

Gene sequence:

>480_bases
GTGAAGGAAGTTCGCTTAACTGATGAGAATGGCGAACAAGTTGGTATCGTATCAATTCAAGATGCTTTGGCGAGAGCGGA
AGATGCTGAATTAGATTTAGTTGAAATCAGCCCTAATGCAGAACCGCCGGTTTGTCGTATTATGAACTACGGTAAGTTCA
TCTACGAAAAAGAAAAAGCTGCAAAAGAGCAGAAGAAAAAACAAAAAGTCGTACAAATGAAGGAAATTAAATTCCGTCCG
GGTACAGACGAAGGCGATTATCAAATTAAGTTACGTAGCATTTTACGTTTCTTGGAAGACGGCGATAAAGTTAAAATTAC
CGTACGTTTCCGTGGTCGTGAAATGGCTCACCAAGATATCGGTTTAGACGTTTTGGATCGCGTTAAAACGGATACGGCTG
AAGTGGCGGTTGTTGAATCGGCACCAGGCAAACTGGAAGGTCGTCAAGCGGTAATGGTCATTGCACCGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
CGATTTTAGAGTAAAACTTACAAGAAGGAATAATACTATTAAACCTGTAAAACGTGTTCAGACAAATCGCGCACATCGTC
TTAATGATGAAATTCGTGGC

Downstream 100 bases:

>100_bases
TTTATTCTTGCATAAAACGGGCGGATCTTATAAAATCCGTCCGTTTTCTCTTTTGTAAAAAAGAGAAACAAAAGCAATCT
ACAGGCACATTTCGCAGCCT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKEVRLTDENGEQVGIVSIQDALARAEDAELDLVEISPNAEPPVCRIMNYGKFIYEKEKAAKEQKKKQKVVQMKEIKFRP
GTDEGDYQIKLRSILRFLEDGDKVKITVRFRGREMAHQDIGLDVLDRVKTDTAEVAVVESAPGKLEGRQAVMVIAPKKK

Sequences:

>Translated_159_residues
MKEVRLTDENGEQVGIVSIQDALARAEDAELDLVEISPNAEPPVCRIMNYGKFIYEKEKAAKEQKKKQKVVQMKEIKFRP
GTDEGDYQIKLRSILRFLEDGDKVKITVRFRGREMAHQDIGLDVLDRVKTDTAEVAVVESAPGKLEGRQAVMVIAPKKK
>Mature_159_residues
MKEVRLTDENGEQVGIVSIQDALARAEDAELDLVEISPNAEPPVCRIMNYGKFIYEKEKAAKEQKKKQKVVQMKEIKFRP
GTDEGDYQIKLRSILRFLEDGDKVKITVRFRGREMAHQDIGLDVLDRVKTDTAEVAVVESAPGKLEGRQAVMVIAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=158, Percent_Identity=74.6835443037975, Blast_Score=226, Evalue=6e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17983; Mature: 17983

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVRLTDENGEQVGIVSIQDALARAEDAELDLVEISPNAEPPVCRIMNYGKFIYEKEKA
CCCEEECCCCCCEEEEEEHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHH
AKEQKKKQKVVQMKEIKFRPGTDEGDYQIKLRSILRFLEDGDKVKITVRFRGREMAHQDI
HHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEECCCHHHHHHC
GLDVLDRVKTDTAEVAVVESAPGKLEGRQAVMVIAPKKK
CHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKEVRLTDENGEQVGIVSIQDALARAEDAELDLVEISPNAEPPVCRIMNYGKFIYEKEKA
CCCEEECCCCCCEEEEEEHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHH
AKEQKKKQKVVQMKEIKFRPGTDEGDYQIKLRSILRFLEDGDKVKITVRFRGREMAHQDI
HHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEECCCHHHHHHC
GLDVLDRVKTDTAEVAVVESAPGKLEGRQAVMVIAPKKK
CHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA