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The map label for this gene is aroB

Identifier: 126207681

GI number: 126207681

Start: 212657

End: 213757

Strand: Reverse

Name: aroB

Synonym: APL_0193

Alternate gene names: 126207681

Gene position: 213757-212657 (Counterclockwise)

Preceding gene: 126207682

Following gene: 126207680

Centisome position: 9.4

GC content: 45.23

Gene sequence:

>1101_bases
ATGTTGCAAGTCAATGTCGAATTAAAAGAGCGTCGTTATCCGATAACCATCGGAGCGGGTTTACTCGGTGATCCGAACAG
CTATTCTTCGCTGAAAGCGGGAGATAAGGTGATGATTGTTTCAAATCCTACCGTCGCCGCACATTATCTTGCAACAGTAA
CAAATACGCTTAACGGATTAGGTTGTAGTGTTGATTCCGTACTCATTCCTGACGGAGAAAAATATAAGACCTTAGATTCG
CTCAATATGATTTTTACCGCATTATTGGAAAAAAATCATAACAGAGACACCACGCTTATCGCTTTAGGCGGCGGTGTGAT
CGGCGATGTTGCGGGTTATGCGGCGGCATCTTATCAACGCGGTATTCGTTTTATCCAAATCCCAACGACATTACTGGCTC
AGGTCGATTCGTCGGTCGGCGGCAAAACGGCGGTTAATCATCCGCTCGGCAAAAATATGATTGGAGCGTTCTATCAGCCG
ATTTCTGTGATTATTGATACGAATACCTTACAAACCCTTCCTAAACGAGAAGTGAGTGCGGGACTTGCCGAAGTCATTAA
GTACGGTGCGATCTTTGATATTCATTTCTTTGAATGGTTGGAAAGTAATATCCATCATTTAGTCGCATTAAAACAAAATG
AATTGGAATACTGTATTCAACGTTGTTGCCAGTTAAAAGCCGATGTGGTGGCGCGTGACGAAACGGAAAAGGGTGACCGA
GCCTTACTCAACTTAGGGCATACGTTCGGTCATGCGATTGAAGCTCATCTCGGATACGGAAATTGGTTACACGGTGAAGC
CGTTTCGGTCGGGATGTTGGAGGCGGCGGAATTATCCCGCATCTTAGGCGATTTATCCGCTCAAGATGTTTCTCGTCTGG
AAAGATTACTGGCACAAGCCGTACTGCCGACAATATCGCCGGACGGAATGGAACCTAGCGAATATTTGCCTTATATGTGG
CGCGATAAAAAAGTACTGGGCGGTCAATTACGTCTTGTCTTGTTAAAATCACTGGGGAAAGCCTACGTTACGGCGCAAGC
GTCGGAGCAACAAGTCTTGTCTGCGATTGAAAGATTTACACAACGTGAGTTTCATGAGTAA

Upstream 100 bases:

>100_bases
ATTGAACTGATTGATAATCTTCAATAAGTTACCCGGGATTAAACGCCCCTATAAATATAATTCGCACATCATTAAATATG
TCGAGATGAGGAAGTAAAAT

Downstream 100 bases:

>100_bases
TAAAAGAGCCTTTCTCAAGTGGGCGGGAGGAAAATACCGCTTAACGACCGAAATTCGTAAACATTTGCCCCCTAAGTCTG
CTCAGGGGGCTTGTTTCGTT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLQVNVELKERRYPITIGAGLLGDPNSYSSLKAGDKVMIVSNPTVAAHYLATVTNTLNGLGCSVDSVLIPDGEKYKTLDS
LNMIFTALLEKNHNRDTTLIALGGGVIGDVAGYAAASYQRGIRFIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQP
ISVIIDTNTLQTLPKREVSAGLAEVIKYGAIFDIHFFEWLESNIHHLVALKQNELEYCIQRCCQLKADVVARDETEKGDR
ALLNLGHTFGHAIEAHLGYGNWLHGEAVSVGMLEAAELSRILGDLSAQDVSRLERLLAQAVLPTISPDGMEPSEYLPYMW
RDKKVLGGQLRLVLLKSLGKAYVTAQASEQQVLSAIERFTQREFHE

Sequences:

>Translated_366_residues
MLQVNVELKERRYPITIGAGLLGDPNSYSSLKAGDKVMIVSNPTVAAHYLATVTNTLNGLGCSVDSVLIPDGEKYKTLDS
LNMIFTALLEKNHNRDTTLIALGGGVIGDVAGYAAASYQRGIRFIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQP
ISVIIDTNTLQTLPKREVSAGLAEVIKYGAIFDIHFFEWLESNIHHLVALKQNELEYCIQRCCQLKADVVARDETEKGDR
ALLNLGHTFGHAIEAHLGYGNWLHGEAVSVGMLEAAELSRILGDLSAQDVSRLERLLAQAVLPTISPDGMEPSEYLPYMW
RDKKVLGGQLRLVLLKSLGKAYVTAQASEQQVLSAIERFTQREFHE
>Mature_366_residues
MLQVNVELKERRYPITIGAGLLGDPNSYSSLKAGDKVMIVSNPTVAAHYLATVTNTLNGLGCSVDSVLIPDGEKYKTLDS
LNMIFTALLEKNHNRDTTLIALGGGVIGDVAGYAAASYQRGIRFIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQP
ISVIIDTNTLQTLPKREVSAGLAEVIKYGAIFDIHFFEWLESNIHHLVALKQNELEYCIQRCCQLKADVVARDETEKGDR
ALLNLGHTFGHAIEAHLGYGNWLHGEAVSVGMLEAAELSRILGDLSAQDVSRLERLLAQAVLPTISPDGMEPSEYLPYMW
RDKKVLGGQLRLVLLKSLGKAYVTAQASEQQVLSAIERFTQREFHE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=356, Percent_Identity=60.1123595505618, Blast_Score=428, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6320332, Length=320, Percent_Identity=39.6875, Blast_Score=207, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_ACTP2 (A3MYR5)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001052906.1
- ProteinModelPortal:   A3MYR5
- SMR:   A3MYR5
- STRING:   A3MYR5
- GeneID:   4849357
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0193
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   A3MYR5
- ProtClustDB:   PRK00002
- BioCyc:   APLE416269:APL_0193-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40043; Mature: 40043

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVNVELKERRYPITIGAGLLGDPNSYSSLKAGDKVMIVSNPTVAAHYLATVTNTLNGL
CEEEEEEHHHCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCC
GCSVDSVLIPDGEKYKTLDSLNMIFTALLEKNHNRDTTLIALGGGVIGDVAGYAAASYQR
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GIRFIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPISVIIDTNTLQTLPKREVSA
CCEEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHCCHHHHHH
GLAEVIKYGAIFDIHFFEWLESNIHHLVALKQNELEYCIQRCCQLKADVVARDETEKGDR
HHHHHHHHCCEEEHHHHHHHHCCHHEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ALLNLGHTFGHAIEAHLGYGNWLHGEAVSVGMLEAAELSRILGDLSAQDVSRLERLLAQA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VLPTISPDGMEPSEYLPYMWRDKKVLGGQLRLVLLKSLGKAYVTAQASEQQVLSAIERFT
HCCCCCCCCCCHHHHCCCCCCCCHHHCHHHHHHHHHHHCHHEEEECCHHHHHHHHHHHHH
QREFHE
HHHCCC
>Mature Secondary Structure
MLQVNVELKERRYPITIGAGLLGDPNSYSSLKAGDKVMIVSNPTVAAHYLATVTNTLNGL
CEEEEEEHHHCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCC
GCSVDSVLIPDGEKYKTLDSLNMIFTALLEKNHNRDTTLIALGGGVIGDVAGYAAASYQR
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GIRFIQIPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPISVIIDTNTLQTLPKREVSA
CCEEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCHHHHCCHHHHHH
GLAEVIKYGAIFDIHFFEWLESNIHHLVALKQNELEYCIQRCCQLKADVVARDETEKGDR
HHHHHHHHCCEEEHHHHHHHHCCHHEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ALLNLGHTFGHAIEAHLGYGNWLHGEAVSVGMLEAAELSRILGDLSAQDVSRLERLLAQA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VLPTISPDGMEPSEYLPYMWRDKKVLGGQLRLVLLKSLGKAYVTAQASEQQVLSAIERFT
HCCCCCCCCCCHHHHCCCCCCCCHHHCHHHHHHHHHHHCHHEEEECCHHHHHHHHHHHHH
QREFHE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA