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The map label for this gene is dam [H]

Identifier: 126207680

GI number: 126207680

Start: 211831

End: 212664

Strand: Reverse

Name: dam [H]

Synonym: APL_0192

Alternate gene names: 126207680

Gene position: 212664-211831 (Counterclockwise)

Preceding gene: 126207681

Following gene: 126207679

Centisome position: 9.35

GC content: 41.49

Gene sequence:

>834_bases
ATGAGTAATAAAAGAGCCTTTCTCAAGTGGGCGGGAGGAAAATACCGCTTAACGACCGAAATTCGTAAACATTTGCCCCC
TAAGTCTGCTCAGGGGGCTTGTTTCGTTGAACCTTTCGTTGGAGCCGGTTCCGTCTTTTTAAATACGGATTACGAACGTT
ATCTACTTGCGGACATTAACCCCGATTTAATTAATTTATTCAATATCATCAAACATGATGTCGAACATTATATTAAAGAA
ACCAAAACGCTTTTTTTAGCTTCCGAAGCGAATACCGCCTCTTTTTATTACGCTCGCCGCCAAGAATTTAATCGTTCGTC
CGATAAGTTCAGGCGCTCGGTACTGTTTCTTTATTTGAATCGTTTCGGCTTTAACGGCTTATGCCGCTATAACCAAAAAC
ATGAATATAACGTACCGTTCGGAGCTTATAAAACGCACTATTTTCCTGAAAACGAATTACGTTTTTTCGCTGAAAAAGCG
CAAAAAGCCGAATTTATCTGTGCCGATTTTGAACAGGTTTTTGCCCGCTTGTATCAAGCTCCCGACAATTATATTGTTTA
TTGTGATCCGCCGTACGCCCCCTTGCAACAAGATACTAATTTTACTCACTATGCCGGCGGCGGGTTCAGCCTCGTGCAGC
AGGAAAAATTAGCTCAGCTCGCAAGACAGGCGCAGACAAATAATATTCCCGTATTGATTTCAAACCATGACACGGCGTTT
ACCCGACAAATCTACCATGGTGCAAAAATCAAAAAAATTAAAGTTCAACGTTCTATCGGGCAGCGAGCCGATTCTCGTAT
TAAAGTAGATGAACTGTTTGCACTCTTCTTATAA

Upstream 100 bases:

>100_bases
CTTGTCTTGTTAAAATCACTGGGGAAAGCCTACGTTACGGCGCAAGCGTCGGAGCAACAAGTCTTGTCTGCGATTGAAAG
ATTTACACAACGTGAGTTTC

Downstream 100 bases:

>100_bases
TTTGCAAAAATTTCTTAAAATCTTACCGCTTGCTTTGCGGAAATAGCCTAACTTAGGAGTAATAATGGCGAATAAATCTG
TAGAACGCCAATCTTGGTCA

Product: DNA adenine methylase

Products: NA

Alternate protein names: DNA adenine methyltransferase; Deoxyadenosyl-methyltransferase; M.HindIV [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSNKRAFLKWAGGKYRLTTEIRKHLPPKSAQGACFVEPFVGAGSVFLNTDYERYLLADINPDLINLFNIIKHDVEHYIKE
TKTLFLASEANTASFYYARRQEFNRSSDKFRRSVLFLYLNRFGFNGLCRYNQKHEYNVPFGAYKTHYFPENELRFFAEKA
QKAEFICADFEQVFARLYQAPDNYIVYCDPPYAPLQQDTNFTHYAGGGFSLVQQEKLAQLARQAQTNNIPVLISNHDTAF
TRQIYHGAKIKKIKVQRSIGQRADSRIKVDELFALFL

Sequences:

>Translated_277_residues
MSNKRAFLKWAGGKYRLTTEIRKHLPPKSAQGACFVEPFVGAGSVFLNTDYERYLLADINPDLINLFNIIKHDVEHYIKE
TKTLFLASEANTASFYYARRQEFNRSSDKFRRSVLFLYLNRFGFNGLCRYNQKHEYNVPFGAYKTHYFPENELRFFAEKA
QKAEFICADFEQVFARLYQAPDNYIVYCDPPYAPLQQDTNFTHYAGGGFSLVQQEKLAQLARQAQTNNIPVLISNHDTAF
TRQIYHGAKIKKIKVQRSIGQRADSRIKVDELFALFL
>Mature_276_residues
SNKRAFLKWAGGKYRLTTEIRKHLPPKSAQGACFVEPFVGAGSVFLNTDYERYLLADINPDLINLFNIIKHDVEHYIKET
KTLFLASEANTASFYYARRQEFNRSSDKFRRSVLFLYLNRFGFNGLCRYNQKHEYNVPFGAYKTHYFPENELRFFAEKAQ
KAEFICADFEQVFARLYQAPDNYIVYCDPPYAPLQQDTNFTHYAGGGFSLVQQEKLAQLARQAQTNNIPVLISNHDTAFT
RQIYHGAKIKKIKVQRSIGQRADSRIKVDELFALFL

Specific function: Methylates DNA within the sequence GATC. Directly involved in methyl-directed DNA mismatch repair [H]

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789789, Length=276, Percent_Identity=56.8840579710145, Blast_Score=314, Evalue=3e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023095
- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 32225; Mature: 32094

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKRAFLKWAGGKYRLTTEIRKHLPPKSAQGACFVEPFVGAGSVFLNTDYERYLLADIN
CCCCCEEEEECCCCEEEEHHHHHCCCCCCCCCCEEECCCCCCCEEEEECCCCEEEEECCC
PDLINLFNIIKHDVEHYIKETKTLFLASEANTASFYYARRQEFNRSSDKFRRSVLFLYLN
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RFGFNGLCRYNQKHEYNVPFGAYKTHYFPENELRFFAEKAQKAEFICADFEQVFARLYQA
HCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDNYIVYCDPPYAPLQQDTNFTHYAGGGFSLVQQEKLAQLARQAQTNNIPVLISNHDTAF
CCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHH
TRQIYHGAKIKKIKVQRSIGQRADSRIKVDELFALFL
HHHHHCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SNKRAFLKWAGGKYRLTTEIRKHLPPKSAQGACFVEPFVGAGSVFLNTDYERYLLADIN
CCCCEEEEECCCCEEEEHHHHHCCCCCCCCCCEEECCCCCCCEEEEECCCCEEEEECCC
PDLINLFNIIKHDVEHYIKETKTLFLASEANTASFYYARRQEFNRSSDKFRRSVLFLYLN
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RFGFNGLCRYNQKHEYNVPFGAYKTHYFPENELRFFAEKAQKAEFICADFEQVFARLYQA
HCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDNYIVYCDPPYAPLQQDTNFTHYAGGGFSLVQQEKLAQLARQAQTNNIPVLISNHDTAF
CCCEEEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHH
TRQIYHGAKIKKIKVQRSIGQRADSRIKVDELFALFL
HHHHHCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]