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The map label for this gene is aroF [H]

Identifier: 126207673

GI number: 126207673

Start: 204535

End: 205596

Strand: Reverse

Name: aroF [H]

Synonym: APL_0185

Alternate gene names: 126207673

Gene position: 205596-204535 (Counterclockwise)

Preceding gene: 126207674

Following gene: 126207672

Centisome position: 9.04

GC content: 43.97

Gene sequence:

>1062_bases
ATGAACACCGTAGTTAATCAGGATAGTTTGCATAATGTGAATATTGTTGATGAAAAAGTATTACTCACCCCGGCCGAGCT
AAAAGCCGAATTACCTTTGCCCGAATATCTACGTAAACAAATTGAAACATCGCGTCGAGAAATCTCGGATATTATCCATA
AACGTGATCAGCGTAAATTAATTGTGATTGGTCCTTGTTCTATTCATGATCCGATTGCCGCCATCGAATACGGCAAAAAA
TTAAAGGCGTTAGCCGATACCGTGTCGGATAAACTTTACATCGTCATGCGTGTATATTTTGAAAAACCGCGTACTACCGT
GGGCTGGAAAGGGCTGATTAACGATCCGAAAATTGACGGGACTTTCGATGTCGAAACCGGCTTACGTGTCGGGCGTAAGC
TCTGTTTGGACCTCGCCGAATTAGGTTTACCGTTAGCAACCGAAGCACTTGATCCGATGACGCCGCAGTATTTGGCTGAT
CTCTTCAGTTGGTCGGCGATTGGTGCCAGAACGACCGAATCGCAAACACACCGAGAATTGGCTTCCGGTTTATCTATGGC
GGTCGGTTTTAAAAACGGCACGGACGGCAGTTTATCCGTAGCGATTAATGCAATGCAATCCGCCGCACAAAGCCATAGCT
TTATCGGCATCAACCAAAAAGGTCAGGTGAATTTATTGCATACTAAGGGTAATCCGGATAGCCATGTGATTCTACGCGGC
GGAAAAACACCTAATTTTGAAAAACAATATGTGGAAGAATGTGAAGCCGCACTACGTAAAGCCGGTTTAGCGGAAGCGAT
TATGATTGACTGTAGCCACGGTAACTCGAATAAAGATTACCGTCGCCAACCGCTTGTTGCGGAAGATGCCTTATCACAAT
TATTAGCCGGCAATACTTCCATTATCGGTTTAATGATCGAAAGCCACTTAAATGCCGGTAACCAATCTTCTGATCAGGCT
TTCAATCAAATGCAATACGGCGTATCCATTACCGACGCTTGTATCGATTGGCAAACGACAGAAAATCTCTTAACCGATTT
TGCTGAAAAATTAAGAGCTTAA

Upstream 100 bases:

>100_bases
GAATCTCTGTCGATGATGTGAAGAAAAAAATAGTTGAAACGCTTGCTGTAAAATTGTAAAGTAACGCTGTATTTAAAATT
TTACAGACAAGGAAATAAAA

Downstream 100 bases:

>100_bases
CACCAGCCTAAAAGGTTCGATATAAAACGAATAAGCGGGCACATTTTGCCAAAAAATTTAAAAATTTGACCGCTTATTTT
ATGAATCTTTCGATAGCATA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNTVVNQDSLHNVNIVDEKVLLTPAELKAELPLPEYLRKQIETSRREISDIIHKRDQRKLIVIGPCSIHDPIAAIEYGKK
LKALADTVSDKLYIVMRVYFEKPRTTVGWKGLINDPKIDGTFDVETGLRVGRKLCLDLAELGLPLATEALDPMTPQYLAD
LFSWSAIGARTTESQTHRELASGLSMAVGFKNGTDGSLSVAINAMQSAAQSHSFIGINQKGQVNLLHTKGNPDSHVILRG
GKTPNFEKQYVEECEAALRKAGLAEAIMIDCSHGNSNKDYRRQPLVAEDALSQLLAGNTSIIGLMIESHLNAGNQSSDQA
FNQMQYGVSITDACIDWQTTENLLTDFAEKLRA

Sequences:

>Translated_353_residues
MNTVVNQDSLHNVNIVDEKVLLTPAELKAELPLPEYLRKQIETSRREISDIIHKRDQRKLIVIGPCSIHDPIAAIEYGKK
LKALADTVSDKLYIVMRVYFEKPRTTVGWKGLINDPKIDGTFDVETGLRVGRKLCLDLAELGLPLATEALDPMTPQYLAD
LFSWSAIGARTTESQTHRELASGLSMAVGFKNGTDGSLSVAINAMQSAAQSHSFIGINQKGQVNLLHTKGNPDSHVILRG
GKTPNFEKQYVEECEAALRKAGLAEAIMIDCSHGNSNKDYRRQPLVAEDALSQLLAGNTSIIGLMIESHLNAGNQSSDQA
FNQMQYGVSITDACIDWQTTENLLTDFAEKLRA
>Mature_353_residues
MNTVVNQDSLHNVNIVDEKVLLTPAELKAELPLPEYLRKQIETSRREISDIIHKRDQRKLIVIGPCSIHDPIAAIEYGKK
LKALADTVSDKLYIVMRVYFEKPRTTVGWKGLINDPKIDGTFDVETGLRVGRKLCLDLAELGLPLATEALDPMTPQYLAD
LFSWSAIGARTTESQTHRELASGLSMAVGFKNGTDGSLSVAINAMQSAAQSHSFIGINQKGQVNLLHTKGNPDSHVILRG
GKTPNFEKQYVEECEAALRKAGLAEAIMIDCSHGNSNKDYRRQPLVAEDALSQLLAGNTSIIGLMIESHLNAGNQSSDQA
FNQMQYGVSITDACIDWQTTENLLTDFAEKLRA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=347, Percent_Identity=65.9942363112392, Blast_Score=493, Evalue=1e-141,
Organism=Escherichia coli, GI1786969, Length=342, Percent_Identity=52.3391812865497, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1787996, Length=328, Percent_Identity=48.1707317073171, Blast_Score=323, Evalue=9e-90,
Organism=Saccharomyces cerevisiae, GI6319726, Length=350, Percent_Identity=50.8571428571429, Blast_Score=348, Evalue=1e-96,
Organism=Saccharomyces cerevisiae, GI6320240, Length=339, Percent_Identity=49.5575221238938, Blast_Score=336, Evalue=4e-93,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38829; Mature: 38829

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVVNQDSLHNVNIVDEKVLLTPAELKAELPLPEYLRKQIETSRREISDIIHKRDQRKL
CCCCCCCCCCCCCEEECCEEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
IVIGPCSIHDPIAAIEYGKKLKALADTVSDKLYIVMRVYFEKPRTTVGWKGLINDPKIDG
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEEEEHHCCCCCCCCCCCCCCCCCCCC
TFDVETGLRVGRKLCLDLAELGLPLATEALDPMTPQYLADLFSWSAIGARTTESQTHREL
EEEHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
ASGLSMAVGFKNGTDGSLSVAINAMQSAAQSHSFIGINQKGQVNLLHTKGNPDSHVILRG
HHCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCEEEEEC
GKTPNFEKQYVEECEAALRKAGLAEAIMIDCSHGNSNKDYRRQPLVAEDALSQLLAGNTS
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCHHHHHHHHHHCCCCC
IIGLMIESHLNAGNQSSDQAFNQMQYGVSITDACIDWQTTENLLTDFAEKLRA
EEEEEHHHHCCCCCCCHHHHHHHHHCCCEEHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTVVNQDSLHNVNIVDEKVLLTPAELKAELPLPEYLRKQIETSRREISDIIHKRDQRKL
CCCCCCCCCCCCCEEECCEEEECHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
IVIGPCSIHDPIAAIEYGKKLKALADTVSDKLYIVMRVYFEKPRTTVGWKGLINDPKIDG
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEEEEHHCCCCCCCCCCCCCCCCCCCC
TFDVETGLRVGRKLCLDLAELGLPLATEALDPMTPQYLADLFSWSAIGARTTESQTHREL
EEEHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
ASGLSMAVGFKNGTDGSLSVAINAMQSAAQSHSFIGINQKGQVNLLHTKGNPDSHVILRG
HHCHHEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCCEEEEEC
GKTPNFEKQYVEECEAALRKAGLAEAIMIDCSHGNSNKDYRRQPLVAEDALSQLLAGNTS
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHCCCHHHHHHHHHHCCCCC
IIGLMIESHLNAGNQSSDQAFNQMQYGVSITDACIDWQTTENLLTDFAEKLRA
EEEEEHHHHCCCCCCCHHHHHHHHHCCCEEHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]