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The map label for this gene is codA [C]

Identifier: 126207661

GI number: 126207661

Start: 190987

End: 191973

Strand: Reverse

Name: codA [C]

Synonym: APL_0173

Alternate gene names: 126207661

Gene position: 191973-190987 (Counterclockwise)

Preceding gene: 126207666

Following gene: 126207652

Centisome position: 8.44

GC content: 43.47

Gene sequence:

>987_bases
ATGAGCCAATTAATTCGTACGCTTAAAAGCCATATTCGTGACGAAATTATTAAAAAAGGCGGTTGGGTAAATTCTCATGC
CCATGCTGACCGCGCATTTACTATGACGCCGGAAAAAATTGCGATTTATCAAAATGCCAACCTTCAGCAAAAATGGGACT
TAGTGGATGAAGTGAAACGTAACTCGACGGTTGATGACTATTACCGTCGTTTTTCTCAAGCTATCGAATTGATGATTTCA
CAAGGGGTAACCGCATTCGGTACTTTTGTGGATATCGACGGCGTATGTGAAGACCGTGCGATTATCGCCGCACACAAAGC
GCGCGAAGTATATAAAAGTGATATCGCTTTAAAATTTGCCAACCAAACTTTAAAAGGGGTTATCGAGCCTACCGCTAAAA
AATGGTTTGATATCGGTTCCGAAATGGTGGATATGATCGGCGGTTTACCTTATCGTGACGAATTGGATTACGGCAAAGGC
TTGGAAGCGATGGATATCTTAATGGATAAAGCCAAATCGCTCGGTAAAATGTTACACGTGCATGTAGACCAATTTAACAC
GCCGAAAGAAAAAGAAACCGAACAATTATGCGATAAGGCGATTGAACACAGTATGCAAGGTCGAGTGGTTGCAATTCACG
GTATTTCTATCGGTGCTCACCCGAAAGAATACCGCAAAATGCTCTACCAAAAAATGCGCGATTCGCAAATGATGGTCATC
GCTTGCCCTATGGCGTGGATTGATAGCGGCCGTAAAGAAGACTTACAACCGTTCCACAACGCACTTACACCGGCGGACGA
ATTAATTCCGGAAGGCATTACCGTAGCAATCGGTACCGATAATATCTGCGACTATATGGTGCCGTTATGTGAAGGCGATA
TGTGGCAAGAACTGAGCTTACTTTCCGCCGGTTGCCGCTTTACCAACTTAGAGGAAATGGCGAATATCGCTTCAATTAAC
GGCAGAAAAGTATTAGGTTTACTCTAA

Upstream 100 bases:

>100_bases
GCTTGGCTCTTTTTTTGGCATTTCAATTTTTAACAGATCTCCTCGCTAGAGATCTTTTTTTTACCTAAATTAAACAAGTC
GTAAAGAGGAATAAATTAAC

Downstream 100 bases:

>100_bases
CCCTCTCATACGACAAAAAAACCGAGCGAAAACGCTCGGTTTTTTATCATCGTTCAATACTAGCGTTTATAAATATCTTC
ACCGTTTCGGCGAGTTTTGA

Product: hypothetical protein

Products: ammonia; Uracil [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSQLIRTLKSHIRDEIIKKGGWVNSHAHADRAFTMTPEKIAIYQNANLQQKWDLVDEVKRNSTVDDYYRRFSQAIELMIS
QGVTAFGTFVDIDGVCEDRAIIAAHKAREVYKSDIALKFANQTLKGVIEPTAKKWFDIGSEMVDMIGGLPYRDELDYGKG
LEAMDILMDKAKSLGKMLHVHVDQFNTPKEKETEQLCDKAIEHSMQGRVVAIHGISIGAHPKEYRKMLYQKMRDSQMMVI
ACPMAWIDSGRKEDLQPFHNALTPADELIPEGITVAIGTDNICDYMVPLCEGDMWQELSLLSAGCRFTNLEEMANIASIN
GRKVLGLL

Sequences:

>Translated_328_residues
MSQLIRTLKSHIRDEIIKKGGWVNSHAHADRAFTMTPEKIAIYQNANLQQKWDLVDEVKRNSTVDDYYRRFSQAIELMIS
QGVTAFGTFVDIDGVCEDRAIIAAHKAREVYKSDIALKFANQTLKGVIEPTAKKWFDIGSEMVDMIGGLPYRDELDYGKG
LEAMDILMDKAKSLGKMLHVHVDQFNTPKEKETEQLCDKAIEHSMQGRVVAIHGISIGAHPKEYRKMLYQKMRDSQMMVI
ACPMAWIDSGRKEDLQPFHNALTPADELIPEGITVAIGTDNICDYMVPLCEGDMWQELSLLSAGCRFTNLEEMANIASIN
GRKVLGLL
>Mature_327_residues
SQLIRTLKSHIRDEIIKKGGWVNSHAHADRAFTMTPEKIAIYQNANLQQKWDLVDEVKRNSTVDDYYRRFSQAIELMISQ
GVTAFGTFVDIDGVCEDRAIIAAHKAREVYKSDIALKFANQTLKGVIEPTAKKWFDIGSEMVDMIGGLPYRDELDYGKGL
EAMDILMDKAKSLGKMLHVHVDQFNTPKEKETEQLCDKAIEHSMQGRVVAIHGISIGAHPKEYRKMLYQKMRDSQMMVIA
CPMAWIDSGRKEDLQPFHNALTPADELIPEGITVAIGTDNICDYMVPLCEGDMWQELSLLSAGCRFTNLEEMANIASING
RKVLGLL

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=292, Percent_Identity=23.2876712328767, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.4.1 [C]

Molecular weight: Translated: 36998; Mature: 36867

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLIRTLKSHIRDEIIKKGGWVNSHAHADRAFTMTPEKIAIYQNANLQQKWDLVDEVKR
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHC
NSTVDDYYRRFSQAIELMISQGVTAFGTFVDIDGVCEDRAIIAAHKAREVYKSDIALKFA
CCCHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NQTLKGVIEPTAKKWFDIGSEMVDMIGGLPYRDELDYGKGLEAMDILMDKAKSLGKMLHV
HHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HVDQFNTPKEKETEQLCDKAIEHSMQGRVVAIHGISIGAHPKEYRKMLYQKMRDSQMMVI
HHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECEECCCHHHHHHHHHHHHCCCCEEEE
ACPMAWIDSGRKEDLQPFHNALTPADELIPEGITVAIGTDNICDYMVPLCEGDMWQELSL
ECCHHHHCCCCHHHHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHH
LSAGCRFTNLEEMANIASINGRKVLGLL
HHHCCCCCCHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
SQLIRTLKSHIRDEIIKKGGWVNSHAHADRAFTMTPEKIAIYQNANLQQKWDLVDEVKR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHC
NSTVDDYYRRFSQAIELMISQGVTAFGTFVDIDGVCEDRAIIAAHKAREVYKSDIALKFA
CCCHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NQTLKGVIEPTAKKWFDIGSEMVDMIGGLPYRDELDYGKGLEAMDILMDKAKSLGKMLHV
HHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HVDQFNTPKEKETEQLCDKAIEHSMQGRVVAIHGISIGAHPKEYRKMLYQKMRDSQMMVI
HHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECEECCCHHHHHHHHHHHHCCCCEEEE
ACPMAWIDSGRKEDLQPFHNALTPADELIPEGITVAIGTDNICDYMVPLCEGDMWQELSL
ECCHHHHCCCCHHHHHHHHHHCCCHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHH
LSAGCRFTNLEEMANIASINGRKVLGLL
HHHCCCCCCHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cytosine; H+; H2O [C]

Specific reaction: Cytosine + H+ + H2O --> ammonia + Uracil [C]

General reaction: Amidine hydrolysis [C]

Inhibitor: 5-Bromo-2-pyrimidone; CDP; CMP; CTP; GDP; GMP; GTP; Guanosine; Thymidine; TTP [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]