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The map label for this gene is gufA [H]

Identifier: 126207584

GI number: 126207584

Start: 101138

End: 101968

Strand: Reverse

Name: gufA [H]

Synonym: APL_0096

Alternate gene names: 126207584

Gene position: 101968-101138 (Counterclockwise)

Preceding gene: 126207585

Following gene: 126207583

Centisome position: 4.48

GC content: 48.13

Gene sequence:

>831_bases
ATGTTTGATCTGTTTTTATCGCTGAACCCGATTTTACAAGCCTTTATCGCCGGTTTGTTTACTTGGGGCTGTACTATTTT
CGGTGCGGCTTTTGTCTATTTTTTTAAAACGGTAAACCGCAAATTACTGGACGTAATGATGGGCTTTGCCGCCGGTGTGA
TGATTGCCGCCTCTTTCTGGTCACTCCTCGCCCCCGCTCTGGAATATGCCGAACCGAGCTACGGTTCGCTCGCATGGCTA
CCGGCTGCGGTCGGCTTCCTTGCCGGCGGTTTTTTCTTGCGAATGATCGATAAAGTCGTCCCGCATTTACATTTAAGCAA
ACCGCTTACCGATGCGGAAGGTATGCCTAAATTTAAACAAGGCTTATCTAAAAGTATGCTACTTTTCTTAGCTATTACTA
TTCACAATATTCCGGAAGGGCTTGCTCTCGGGGTGACATTCGGTGCTTTAGCTTCAAATGTAGCCGATCATCAAGCGATG
CTCACCGGGGCAATCGGCTTGGCTATCGGTATCGGTTTACAAAATATTCCGGAAGGGTCATCATTATCGTTACCGATTCG
AGGCGAAGGCAAAAGCCGTAAACAAGCCTTTTTATGGGGAGCGATGTCCGCGATTGTCGAACCAATTGCCGCCGTTATCG
GCGCCGCATTCGTGCTTTCTATGACGGCAATTCTACCTTATGCGCTTGCATTCGCTGCCGGAGCGATGATTTTCGTGGTG
GTGGAAGAGCTGATTCCCGAGTCGCAAAGCGGCGGTAACACCGATATTGCCACCTTGGGTTTAATGGTGGGATTTGTAAT
TATGATGGTATTAGATGTGGCTTTAGGCTAA

Upstream 100 bases:

>100_bases
GGTCAAATTTCGCTAGAAAATTGCAAAATAATTTGCAAAAATTCGAGCAAATTCGACCGCTTTTTGATCTCCGTTTGAGA
TCTCTTTATTAGGAATGCAA

Downstream 100 bases:

>100_bases
GCTACCGAACATAACGCTTCATCTAAAAAGGATTGATATGATTTGGTATAAGGCACTGTTTTCGTTTCAAGGGCGGCTTA
ACCGCCAAGGCTTTTGGATC

Product: zinc transporter family protein ZIP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MFDLFLSLNPILQAFIAGLFTWGCTIFGAAFVYFFKTVNRKLLDVMMGFAAGVMIAASFWSLLAPALEYAEPSYGSLAWL
PAAVGFLAGGFFLRMIDKVVPHLHLSKPLTDAEGMPKFKQGLSKSMLLFLAITIHNIPEGLALGVTFGALASNVADHQAM
LTGAIGLAIGIGLQNIPEGSSLSLPIRGEGKSRKQAFLWGAMSAIVEPIAAVIGAAFVLSMTAILPYALAFAAGAMIFVV
VEELIPESQSGGNTDIATLGLMVGFVIMMVLDVALG

Sequences:

>Translated_276_residues
MFDLFLSLNPILQAFIAGLFTWGCTIFGAAFVYFFKTVNRKLLDVMMGFAAGVMIAASFWSLLAPALEYAEPSYGSLAWL
PAAVGFLAGGFFLRMIDKVVPHLHLSKPLTDAEGMPKFKQGLSKSMLLFLAITIHNIPEGLALGVTFGALASNVADHQAM
LTGAIGLAIGIGLQNIPEGSSLSLPIRGEGKSRKQAFLWGAMSAIVEPIAAVIGAAFVLSMTAILPYALAFAAGAMIFVV
VEELIPESQSGGNTDIATLGLMVGFVIMMVLDVALG
>Mature_276_residues
MFDLFLSLNPILQAFIAGLFTWGCTIFGAAFVYFFKTVNRKLLDVMMGFAAGVMIAASFWSLLAPALEYAEPSYGSLAWL
PAAVGFLAGGFFLRMIDKVVPHLHLSKPLTDAEGMPKFKQGLSKSMLLFLAITIHNIPEGLALGVTFGALASNVADHQAM
LTGAIGLAIGIGLQNIPEGSSLSLPIRGEGKSRKQAFLWGAMSAIVEPIAAVIGAAFVLSMTAILPYALAFAAGAMIFVV
VEELIPESQSGGNTDIATLGLMVGFVIMMVLDVALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577422, Length=335, Percent_Identity=39.1044776119403, Blast_Score=185, Evalue=3e-47,
Organism=Homo sapiens, GI229577418, Length=150, Percent_Identity=55.3333333333333, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1789419, Length=263, Percent_Identity=27.7566539923954, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17507805, Length=320, Percent_Identity=43.75, Blast_Score=245, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24652846, Length=169, Percent_Identity=49.7041420118343, Blast_Score=151, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 29064; Mature: 29064

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]