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The map label for this gene is yafC [C]

Identifier: 126175718

GI number: 126175718

Start: 4140380

End: 4141291

Strand: Direct

Name: yafC [C]

Synonym: Sbal_3521

Alternate gene names: 126175718

Gene position: 4140380-4141291 (Clockwise)

Preceding gene: 126175711

Following gene: 126175720

Centisome position: 80.75

GC content: 47.7

Gene sequence:

>912_bases
ATGCCAGATTTAAACGGTATGATGCTATTTGCAGCCGTAGTTAGAGCTAAGGGATTCTCCCAAGCTGCACGTGAAACCGG
CCACCCAAAATCCACCATAAGTCGCAAAATCGCGCAGCTTGAAGAACAACTTGGCGTGCGATTACTACAGCGCGACACCC
GTAACTTGAGTCTGACCCAAGTCGGGGCACTCTTTTACCAACACTGTGATTCCATTCGCAATGAGGTGGAAGCGGCCAAG
GCTGTTATCGAGAATACTCACGATGATGTGTCAGGATCATTACGGATTGCGATCCCGGTGTCATTTAGCCAAGAACTTAT
CGCTAACCTCTGTAGCGGATTTATGCGTTTATATCCCAATGTTGAATTGGATGTCCAGTTTACCGACAACGATATTGGTT
TGGTCGGCGAAGGATATGACATAGCCATCAAATATGGCCCACTTCAATCATCGGACTTAGTCGCACGATTACTGTTTGAA
CGCCAACCGATTTTAGTCGCAAGCCCAGGTTACTTAAAACTCAAAGGCACGCCCGCAACGCCAAAAGAACTCAGCCTGCA
CAGTGGTATTTTATTGGGGACTTCTCGCTCGGCGCCGATTTGGCCACTGGGTAAAGGTTCACGGAAAACCATGGCAAACT
TCCAGCGTAAAGTGCGGGTCAACAGCCCGATAATGGTGAAGCAATTAGCCATGGATGATTTTGGCATCGCCATGTTATCC
AATTCGGCCTGTAAGACCGAACTCGCTAATGGACAGCTAGTACCGATTTTACAAGAATGGCCGATTGAACCCTTTAAGGT
TTACGGGGTTTATTCGAGTCGACGTCAACTGGCCACTAACATCAGCGTCTTTTTGGATTTCTTCGTAAAACGCTTCAGCA
GCCAAGAAAGCCTGCAATCCCTCATGGGTTAA

Upstream 100 bases:

>100_bases
TCTGAAAATTTTTAGCCAATAAATATAACTTTGTTATCCCGTCAAATGCCATTAAACTGCATAAGACGCTATGTTCCAAA
TATGAGACAGTGGGAAAAAC

Downstream 100 bases:

>100_bases
AGTTTCCCGTCGCATAAAGGAAACCTGTTTCAAAAAGCCTAATAAAACAGCCTAGATCTGAGTCTAGGCTTTTAGCATCA
TGATTCATGTCAGCCAAGTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEQLGVRLLQRDTRNLSLTQVGALFYQHCDSIRNEVEAAK
AVIENTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPNVELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFE
RQPILVASPGYLKLKGTPATPKELSLHSGILLGTSRSAPIWPLGKGSRKTMANFQRKVRVNSPIMVKQLAMDDFGIAMLS
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISVFLDFFVKRFSSQESLQSLMG

Sequences:

>Translated_303_residues
MPDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEQLGVRLLQRDTRNLSLTQVGALFYQHCDSIRNEVEAAK
AVIENTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPNVELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFE
RQPILVASPGYLKLKGTPATPKELSLHSGILLGTSRSAPIWPLGKGSRKTMANFQRKVRVNSPIMVKQLAMDDFGIAMLS
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISVFLDFFVKRFSSQESLQSLMG
>Mature_302_residues
PDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEQLGVRLLQRDTRNLSLTQVGALFYQHCDSIRNEVEAAKA
VIENTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPNVELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFER
QPILVASPGYLKLKGTPATPKELSLHSGILLGTSRSAPIWPLGKGSRKTMANFQRKVRVNSPIMVKQLAMDDFGIAMLSN
SACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISVFLDFFVKRFSSQESLQSLMG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=34.8432055749129, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=29.8305084745763, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=27.5510204081633, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=28.6195286195286, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=26.0416666666667, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=24.8275862068966, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=24.2214532871972, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789173, Length=265, Percent_Identity=25.6603773584906, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788706, Length=261, Percent_Identity=26.4367816091954, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI157672245, Length=162, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786448, Length=296, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787601, Length=168, Percent_Identity=25, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33480; Mature: 33349

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEQLGVRLLQRDTRNLSLTQ
CCCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VGALFYQHCDSIRNEVEAAKAVIENTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
VELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFERQPILVASPGYLKLKGTPAT
CEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCCC
PKELSLHSGILLGTSRSAPIWPLGKGSRKTMANFQRKVRVNSPIMVKQLAMDDFGIAMLS
CHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHC
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISVFLDFFVKRFSSQESLQS
CCHHHHHCCCCCEEEEHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LMG
HCC
>Mature Secondary Structure 
PDLNGMMLFAAVVRAKGFSQAARETGHPKSTISRKIAQLEEQLGVRLLQRDTRNLSLTQ
CCCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VGALFYQHCDSIRNEVEAAKAVIENTHDDVSGSLRIAIPVSFSQELIANLCSGFMRLYPN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
VELDVQFTDNDIGLVGEGYDIAIKYGPLQSSDLVARLLFERQPILVASPGYLKLKGTPAT
CEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCEEEEECCCCC
PKELSLHSGILLGTSRSAPIWPLGKGSRKTMANFQRKVRVNSPIMVKQLAMDDFGIAMLS
CHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHC
NSACKTELANGQLVPILQEWPIEPFKVYGVYSSRRQLATNISVFLDFFVKRFSSQESLQS
CCHHHHHCCCCCEEEEHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LMG
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]