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The map label for this gene is panC [H]

Identifier: 126175692

GI number: 126175692

Start: 4095233

End: 4096078

Strand: Direct

Name: panC [H]

Synonym: Sbal_3495

Alternate gene names: 126175692

Gene position: 4095233-4096078 (Clockwise)

Preceding gene: 126175691

Following gene: 126175694

Centisome position: 79.87

GC content: 48.94

Gene sequence:

>846_bases
ATGATCACTAGCGCCCATATTGATGATATTCGCACCCAAGTGCGTGCATGGCGTGCCAAGGGCGAAACCGTCGCCTTTGT
GCCTACCATGGGTAATCTCCATCAGGGACACATTACTTTAGTCAAAGAAGCCGCGAGCAAGTGTGACCATGTGGTAGCCT
CTATTTTCGTTAATCCAATGCAATTTGGTCAGAACGAAGATCTGGATGCTTACCCACGCACACTCGCTGCCGACAGCGAA
GCCCTCACGGCTGCTGGCGCTGAGCTATTATTCACCCCAACGCCAGCCGTGATGTATCCCAAAGGTCTAGAGCAACAAAC
CTATGTCGAAGTCCCTGGGATTTCCAACGTGCTTTGTGGTGCTAGCCGTCCGGGGCATTTCCGTGGCGTTGCGACTATCG
TTTGTAAACTGTTTAACATAGTGCAGCCCGATGTGGCGCTATTCGGTAATAAAGACTATCAACAGCTATTAGTGATCAAA
ACTATGGTTGAAGACTTGTCATTACCAATTGAAATTATCGGTGTCGATACCATACGTGAGGACTCAGGTTTAGCCATGAG
TTCGCGTAATGGTTACCTCACTGCCGCAGAAAAAGCCGCTGCGCCTGCACTAAAACAAGCCATAGATGCCATGGCCGCAG
GGATCAAGCAAGGCGAAAGCTTTGAGCAAGTGACTGAGCAAGCAAAAGCCAGTTTAATCGCAGCAGGTTTTACGCCGGAT
TACCTCGAAATTCGCCACGCTCACACGCTTGAACAAGCCCAAAATCAACACCAAGCCTTAGTGATTTTAACAGCGGCCTA
TATAGGCAAAGCGCGACTTATCGATAACTTAAGGTTCGATAGCTAA

Upstream 100 bases:

>100_bases
TTCTGCCGTGCGTGCTTATATCGACGAAGTTGCCCAAGGAACATTCCCTGGCGAAGAACACACTTTTAACTAATAACCGA
TTTATGCAAGGTAAGGCTCA

Downstream 100 bases:

>100_bases
CTCTTAGCGTTATCAATCAATAAAAGGAGCGCTCGCTCCTTTTTTTATGTTTTCAATCTCCCTACCACACTCAATTTTCT
TGTTTAGAATCAACCCTAGC

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MITSAHIDDIRTQVRAWRAKGETVAFVPTMGNLHQGHITLVKEAASKCDHVVASIFVNPMQFGQNEDLDAYPRTLAADSE
ALTAAGAELLFTPTPAVMYPKGLEQQTYVEVPGISNVLCGASRPGHFRGVATIVCKLFNIVQPDVALFGNKDYQQLLVIK
TMVEDLSLPIEIIGVDTIREDSGLAMSSRNGYLTAAEKAAAPALKQAIDAMAAGIKQGESFEQVTEQAKASLIAAGFTPD
YLEIRHAHTLEQAQNQHQALVILTAAYIGKARLIDNLRFDS

Sequences:

>Translated_281_residues
MITSAHIDDIRTQVRAWRAKGETVAFVPTMGNLHQGHITLVKEAASKCDHVVASIFVNPMQFGQNEDLDAYPRTLAADSE
ALTAAGAELLFTPTPAVMYPKGLEQQTYVEVPGISNVLCGASRPGHFRGVATIVCKLFNIVQPDVALFGNKDYQQLLVIK
TMVEDLSLPIEIIGVDTIREDSGLAMSSRNGYLTAAEKAAAPALKQAIDAMAAGIKQGESFEQVTEQAKASLIAAGFTPD
YLEIRHAHTLEQAQNQHQALVILTAAYIGKARLIDNLRFDS
>Mature_281_residues
MITSAHIDDIRTQVRAWRAKGETVAFVPTMGNLHQGHITLVKEAASKCDHVVASIFVNPMQFGQNEDLDAYPRTLAADSE
ALTAAGAELLFTPTPAVMYPKGLEQQTYVEVPGISNVLCGASRPGHFRGVATIVCKLFNIVQPDVALFGNKDYQQLLVIK
TMVEDLSLPIEIIGVDTIREDSGLAMSSRNGYLTAAEKAAAPALKQAIDAMAAGIKQGESFEQVTEQAKASLIAAGFTPD
YLEIRHAHTLEQAQNQHQALVILTAAYIGKARLIDNLRFDS

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=268, Percent_Identity=51.865671641791, Blast_Score=285, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6322046, Length=299, Percent_Identity=37.7926421404682, Blast_Score=188, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 30388; Mature: 30388

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSAHIDDIRTQVRAWRAKGETVAFVPTMGNLHQGHITLVKEAASKCDHVVASIFVNPM
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QFGQNEDLDAYPRTLAADSEALTAAGAELLFTPTPAVMYPKGLEQQTYVEVPGISNVLCG
HCCCCCCCCCCCHHHHCCCHHHHHCCCEEEECCCCCEECCCCCCCCEEEECCCCCHHHCC
ASRPGHFRGVATIVCKLFNIVQPDVALFGNKDYQQLLVIKTMVEDLSLPIEIIGVDTIRE
CCCCCCHHHHHHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEC
DSGLAMSSRNGYLTAAEKAAAPALKQAIDAMAAGIKQGESFEQVTEQAKASLIAAGFTPD
CCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCC
YLEIRHAHTLEQAQNQHQALVILTAAYIGKARLIDNLRFDS
HHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MITSAHIDDIRTQVRAWRAKGETVAFVPTMGNLHQGHITLVKEAASKCDHVVASIFVNPM
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QFGQNEDLDAYPRTLAADSEALTAAGAELLFTPTPAVMYPKGLEQQTYVEVPGISNVLCG
HCCCCCCCCCCCHHHHCCCHHHHHCCCEEEECCCCCEECCCCCCCCEEEECCCCCHHHCC
ASRPGHFRGVATIVCKLFNIVQPDVALFGNKDYQQLLVIKTMVEDLSLPIEIIGVDTIRE
CCCCCCHHHHHHHHHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEC
DSGLAMSSRNGYLTAAEKAAAPALKQAIDAMAAGIKQGESFEQVTEQAKASLIAAGFTPD
CCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCC
YLEIRHAHTLEQAQNQHQALVILTAAYIGKARLIDNLRFDS
HHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA