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The map label for this gene is ydhC [H]

Identifier: 126174385

GI number: 126174385

Start: 2510733

End: 2512004

Strand: Direct

Name: ydhC [H]

Synonym: Sbal_2168

Alternate gene names: 126174385

Gene position: 2510733-2512004 (Clockwise)

Preceding gene: 126174378

Following gene: 126174390

Centisome position: 48.97

GC content: 46.86

Gene sequence:

>1272_bases
ATGAAAACGTCTAGTAACACCTTTGTAAACATAAAGTTCTTTATGTTTCTATTCTATTTAGCCATGTTGAGCATGCTCGG
CTTTATTGCCACTGACATGTATTTGCCTGCTTTCAAAGCAATTGAAGGCTCGCTTAACAGTACCCCGTCACAGGTGGCGA
TGTCGCTGACCTGTTTCCTGGCGGGTCTTGCCTTAGGTCAGCTACTTTATGGCCCCTTAGTCAATAAAATCGGCAAACGT
TGGGCACTGATTTTTGGCCTAGTGCTATTTGCCGTTGCCAGCGTGTTTATTGCCAACAGTGATTCTATCCTAATGCTCAA
TACCGCGCGCTTCTTCCAAGCGATTGGCGCCTGTAGTGCAGGGGTTATTTGGCAAGCGATTGTGGTTGAGCAATATGATG
CCGATAAAGCCCAAGGTATTTTCAGTAACATTATGCCACTGGTCGCATTATCGCCTGCATTAGCACCGATCCTTGGCGCT
TACATTCTGAACGAATTAGGCTGGCGTGCAATCTTTATCTCTTTGTGTGTTATCGCTTTTCTACTGATATTGATGACCTT
GTACTTTGTGCCAGGCAAGCGTCAGCATACACACACTGAACATGCTGCGGTATCTTATGGGCAAATTTTGAAAAACACCC
GCTATTTAGGCAACGTCGTGATCTTCGGCGCCTGTTCCGGTGCTTTCTTTGCTTATCTAACCGTATGGCCGATTGTGATG
GAAATGCACGGTTATCTGCCAACTGAAATCGGCCTTAGCTTTATCCCGCAAACCATCATGTTTATTGTCGGTGGTTATGC
GAGTAAGTTACTGATAAAACGCATTGGCGGGCATCAAACACTGAATATCTTGTTGTCGATTTTCGCAGCCTGCGTTATTT
CGATCATCATGTTCACGCTGATTTTCCCAGCAAGCACGATTTTCCCACTGCTTATTTCGTTCTCGATTTTGGCCGCAGCT
AATGGCGCCATTTACCCGATAGTCGTGAACAGCGCGCTACAGCAGTTTAGTCAGAATGCCGCTAAGGCCGCAGGATTACA
GAACTTCTTGCAGATCAGCATTGCCTTTGGTGCATCTAGCTTAGTCGCTATGTGGGCAAGCCTAGGTGAAGTAGCGATCG
GTTGGGGCATCCTATGTTGCGCTATCTTAGTTGTGGTCGGCTATGTGCTGAAGAGCCAACAAGGGTGGGGCGATTTTGCC
AAACATTTCACTAAGCCAGATCCCGCACGTGTTGGCATAGTGGCCGATGTGAAGCAAAATCCAGCGGATTGA

Upstream 100 bases:

>100_bases
CAATGAAAATAATTGATAGCACAAGTCAAAAATAAACGTTTCCAATAGATTTAACAAGTCATTAGACTGCACGCTTTAGT
CAATCCGACCCGATTATTTT

Downstream 100 bases:

>100_bases
GTGTAATAGCAACAATCGGCGCATAATTGAGAGTTAGTGCTTTACAGTCAACACACTTACTTATATTATGCGCCTCGTTC
GGAGGGGTGGCAGAGTGGTT

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFLAGLALGQLLYGPLVNKIGKR
WALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSAGVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGA
YILNELGWRAIFISLCVIAFLLILMTLYFVPGKRQHTHTEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTLIFPASTIFPLLISFSILAAA
NGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASSLVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWGDFA
KHFTKPDPARVGIVADVKQNPAD

Sequences:

>Translated_423_residues
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFLAGLALGQLLYGPLVNKIGKR
WALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSAGVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGA
YILNELGWRAIFISLCVIAFLLILMTLYFVPGKRQHTHTEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTLIFPASTIFPLLISFSILAAA
NGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASSLVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWGDFA
KHFTKPDPARVGIVADVKQNPAD
>Mature_423_residues
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFLAGLALGQLLYGPLVNKIGKR
WALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSAGVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGA
YILNELGWRAIFISLCVIAFLLILMTLYFVPGKRQHTHTEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTLIFPASTIFPLLISFSILAAA
NGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASSLVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWGDFA
KHFTKPDPARVGIVADVKQNPAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=384, Percent_Identity=42.4479166666667, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1788509, Length=269, Percent_Identity=28.2527881040892, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790146, Length=240, Percent_Identity=25, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787065, Length=289, Percent_Identity=24.5674740484429, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790794, Length=228, Percent_Identity=22.8070175438596, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082312, Length=363, Percent_Identity=22.038567493113, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45695; Mature: 45695

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFL
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AGLALGQLLYGPLVNKIGKRWALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHH
GVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGAYILNELGWRAIFISLCVIAF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLILMTLYFVPGKRQHTHTEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEECCHHHHHHHHHHHHHHH
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IFPASTIFPLLISFSILAAANGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASS
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWGDFAKHFTKPDPARVGIVADVKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEECCCC
PAD
CCC
>Mature Secondary Structure
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFL
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AGLALGQLLYGPLVNKIGKRWALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHH
GVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGAYILNELGWRAIFISLCVIAF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLILMTLYFVPGKRQHTHTEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEECCHHHHHHHHHHHHHHH
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IFPASTIFPLLISFSILAAANGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASS
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWGDFAKHFTKPDPARVGIVADVKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEEEEECCCC
PAD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]