Click here to switch to the map view.

The map label for this gene is lolA

Identifier: 126174374

GI number: 126174374

Start: 2503266

End: 2503892

Strand: Direct

Name: lolA

Synonym: Sbal_2157

Alternate gene names: 126174374

Gene position: 2503266-2503892 (Clockwise)

Preceding gene: 126174373

Following gene: 126174375

Centisome position: 48.82

GC content: 44.34

Gene sequence:

>627_bases
ATGAAAAAACGATTATGCGCTGTGTTGTTAGCTTCACCTTTGCTATTTAGCGCGGCTGTGTTTGCCGATGATGCACAGCA
GCTCAGAGACAAACTGATTGGTACTGCATCACTAAAAGCCGATTTCAAACAAACCGTGACTGACGTCAATAAAAAGGTCA
TTCAGACGGGTTCTGGTATCTTTGCCTTGGCGTATCCAAATCAGTTTTATTGGCATTTAACTCAGCCCGATGAATCGCAA
ATTGTCGCCGATGGTAAAGATTTATGGATCTACAATCCCTTCGCCGAAGAAGTGGTCATCATGGATTTTGCCGAGGCAAT
CAATGCTTCGCCTATCGCCTTGTTAGTCCACCGCGACGATGCCACTTGGTCACAGTATTCAGTCACTAAGCAACAAGACT
GCTATGAGATCAAACCTAAGGCGATTGATTCGGGCATATTGTCCGTCAAGGTGTGTTTCAAAAATGCCCAGTTAGCCAAC
TTTAATGTTGCCGATGACAAAGGTAACTTGAGCCAATTTGATTTGAGCAATCAGCAAGCGATTACTGATAAAGACAAAGC
GCTGTTCAGCTTTGTGCTGCCTGACAATGTCGATGTTGATGATCAACGTCGTAAAACAGCGCACTAG

Upstream 100 bases:

>100_bases
GTAACCGTGAGGTCTTAGCGCCGCCGGCACCAAAACATTATTAAGCCGCGCTAAGGCGTGGCTTTGATACACCCAAGGGT
TTTACCGGGTAAGGAATAAA

Downstream 100 bases:

>100_bases
GCGATAGCGTGAGCAGTTTATCCTTTAATTTCGCCCCAGACTTTCGTCCCTTGGCCGCACGCATGCGGCCAAGAACGATC
GCCGAGTACATAGGCCAAGC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYSVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLAN
FNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH

Sequences:

>Translated_208_residues
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYSVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLAN
FNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH
>Mature_208_residues
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYSVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLAN
FNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=200, Percent_Identity=34, Blast_Score=124, Evalue=3e-30,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_SHEB2 (B8EET4)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358115.1
- ProteinModelPortal:   B8EET4
- SMR:   B8EET4
- GeneID:   7085998
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2192
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- ProtClustDB:   CLSK906679
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23206; Mature: 23206

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCE
FALAYPNQFYWHLTQPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDD
EEEECCCCEEEEECCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCC
ATWSQYSVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLANFNVADDKGNLSQFDLSNQQA
CCCCCEECCCCCCCEECCCCHHCCCEEEEEEEECCCEEEECEECCCCCCCCEECCCCCCC
ITDKDKALFSFVLPDNVDVDDQRRKTAH
CCCCCCEEEEEECCCCCCCCCCHHCCCC
>Mature Secondary Structure
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCE
FALAYPNQFYWHLTQPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDD
EEEECCCCEEEEECCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCC
ATWSQYSVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLANFNVADDKGNLSQFDLSNQQA
CCCCCEECCCCCCCEECCCCHHCCCEEEEEEEECCCEEEECEECCCCCCCCEECCCCCCC
ITDKDKALFSFVLPDNVDVDDQRRKTAH
CCCCCCEEEEEECCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA