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The map label for this gene is dppA [H]

Identifier: 126173849

GI number: 126173849

Start: 1886746

End: 1888371

Strand: Reverse

Name: dppA [H]

Synonym: Sbal_1615

Alternate gene names: 126173849

Gene position: 1888371-1886746 (Counterclockwise)

Preceding gene: 126173850

Following gene: 126173848

Centisome position: 36.83

GC content: 48.52

Gene sequence:

>1626_bases
ATGAGTGTGCTAATTAGACGCCTGTGCCTAACAACTGCAGTTTCTTGCATGAGTTGGTTGTTGGTCGCGTGTGGCCCCCA
ACGACTCCCTTCCGGTTTGGTGTATTGCTCCGAAGGGAACCCTGAGTCTTTTAATCCACAATTGGTGACGTCTGGCACGA
CAATCGATGCCACCTCGCACCAAATTTATAGTCGCTTAGTGGATTATGATACCCAGTCAGGCAAGCTTGTCCCTGCCTTG
GCGACGAGTTGGGCTATGTCCGATGATGGCTTAAGCTATCGCTTCACCCTCAGGGAAAACGTGCAGTTCCAGCATTCGAA
GCGGTTTACCCCGACACGGCCCTTCAATGCCGACGATGTGTTGTTCTCCTTTAAGCGTATTATCGATACCCAGCATCCTT
ATCATTTTGTCTCCCGCACGGGTTATCCCTTCTTCCAAAGTATTGGCTTTTCTGAACAAGTTAAAGGGATAGAAAAGATA
AACGATCATGAAGTGGTCTTTTATTTAACCCGCAAAGACGCTTCTTTTCTGTCAAATCTGGCCACCGACTTTGCGGTGAT
CTTATCCGATGAATACGCGCAGCAGCAGTTAGCCTTGGGTCATCCTGAAAACGTCGACCACTTTGCCATTGGCACTGGGC
CGTTCACTTTAGTTCAGTACGCGAAAAACGAATATATTCGCTATCGTCGTCATCCTGACTTTTGGGGCGAACCAGCAAAA
ATCGATATGCTCGTATTTGATATCACGCCCAAAAGTACCGTCAGACTCGCAAAACTTATCGCGGGCGATTGCAGTGTATC
TGCGCTGCCCAAAGCGGGTGAGCTGCCTGTTATCAAGCAACATGAAGAATTAAATATTGAGTCACAACCTGGACTTAACG
TAGCATTTTGGGCCTTTAATACGCAAAAGCCGCCACTGAATGATGTCCGAGTGCGCCGCGCACTGGCCTATGCGGTCGAT
AAACAAAATATCCTGCGGGCGGTTTATCAAAATACCGCCATTGAAGCCACTGGCGTTCTGCCGCCAGCATCTTGGGCCTA
CGACAATAACAAAGGGCTTGTGGATTACAATCCGAAAAAAGCGCGCGACCTATTAAAAGAAGCGGGCATTAAAAATCTCA
GTATCGATATTTGGGCCATGCCAGTCGCCCGCGCCTATAACCCCAATGCGTTGAAAACGGCTGAATTAATTCAATCGGAT
CTAGCCAACATAGGCGTCAAAGTGAACATCGTCAGTTACGACTGGAGCGTGTTTAGTCAGCGGCTCAGCCGCGACGACTA
TGATTCAGTGTTAATTGGCTGGAATGCTGATAACAGTGATCCCGATAACTTCTTTACTCCACTGCTGAGCTGCGCCGCAA
TGCAGTCGAACAACAATCGTTCGCGCTGGTGTAACCCTGAGTTTGATGCCATCTTAGATAGCGCAAGGGAAGTGTCAGAT
CAGGGCGAATGTAAAGTCATTTATCAACAAGCAGAAGCCTTTTTAGCTGAACAAGTGCCTATGCTGAGTCTGGCCCATGC
CAAGCGTGTGGCGTTAACTCGCCATGATGTCAAAGACATGCAACTCACGCCTTTTGGTGGCATTTCCTTCGCCCACACTA
GCCAAGCACAAGAGGAGGCGAATTAA

Upstream 100 bases:

>100_bases
TAAAAAATACAATTTACTTGATAAAGCATAAGCAGATTGCCCATGGGGGAGATGCACTGCTAAAATAGCCGTTCATAGTC
GATAAAATAATGATTTATAA

Downstream 100 bases:

>100_bases
TGTTTAAATACCTACTGCGCCGCCTCAATTTGTTTCTTGCTACTTCGTTAGTCATGGTAGGTGTCTTATTTTACGCCACG
GGCTTATTTCCGGTAGATCG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSVLIRRLCLTTAVSCMSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKLVPAL
ATSWAMSDDGLSYRFTLRENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKI
NDHEVVFYLTRKDASFLSNLATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAK
IDMLVFDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALAYAVD
KQNILRAVYQNTAIEATGVLPPASWAYDNNKGLVDYNPKKARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSD
LANIGVKVNIVSYDWSVFSQRLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDSAREVSD
QGECKVIYQQAEAFLAEQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAHTSQAQEEAN

Sequences:

>Translated_541_residues
MSVLIRRLCLTTAVSCMSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKLVPAL
ATSWAMSDDGLSYRFTLRENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKI
NDHEVVFYLTRKDASFLSNLATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAK
IDMLVFDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALAYAVD
KQNILRAVYQNTAIEATGVLPPASWAYDNNKGLVDYNPKKARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSD
LANIGVKVNIVSYDWSVFSQRLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDSAREVSD
QGECKVIYQQAEAFLAEQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAHTSQAQEEAN
>Mature_540_residues
SVLIRRLCLTTAVSCMSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKLVPALA
TSWAMSDDGLSYRFTLRENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKIN
DHEVVFYLTRKDASFLSNLATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAKI
DMLVFDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALAYAVDK
QNILRAVYQNTAIEATGVLPPASWAYDNNKGLVDYNPKKARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSDL
ANIGVKVNIVSYDWSVFSQRLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDSAREVSDQ
GECKVIYQQAEAFLAEQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAHTSQAQEEAN

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=503, Percent_Identity=45.3280318091451, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1787551, Length=509, Percent_Identity=42.6326129666012, Blast_Score=440, Evalue=1e-125,
Organism=Escherichia coli, GI1787762, Length=491, Percent_Identity=25.8655804480652, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1787052, Length=487, Percent_Identity=24.0246406570842, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789887, Length=549, Percent_Identity=23.1329690346084, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1789397, Length=503, Percent_Identity=25.2485089463221, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787495, Length=467, Percent_Identity=24.4111349036403, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87081878, Length=526, Percent_Identity=23.384030418251, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60669; Mature: 60538

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIRRLCLTTAVSCMSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSH
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHH
QIYSRLVDYDTQSGKLVPALATSWAMSDDGLSYRFTLRENVQFQHSKRFTPTRPFNADDV
HHHHHHHCCCCCCCEEEHHHHHHHEECCCCCEEEEEEECCCCCHHCCCCCCCCCCCHHHH
LFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKINDHEVVFYLTRKDASFLSNL
HHHHHHHHCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
ATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAK
HHHHEEEECCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHEEECCCCCCCCCCCE
IDMLVFDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFN
EEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECHHHCCCCCCCCCEEEEEEEC
TQKPPLNDVRVRRALAYAVDKQNILRAVYQNTAIEATGVLPPASWAYDNNKGLVDYNPKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEECCHHH
ARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSDLANIGVKVNIVSYDWSVFSQ
HHHHHHHCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHHH
RLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDSAREVSD
HHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
QGECKVIYQQAEAFLAEQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAHTSQAQEEA
CCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCEECCCCCHHHHC
N
C
>Mature Secondary Structure 
SVLIRRLCLTTAVSCMSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHH
QIYSRLVDYDTQSGKLVPALATSWAMSDDGLSYRFTLRENVQFQHSKRFTPTRPFNADDV
HHHHHHHCCCCCCCEEEHHHHHHHEECCCCCEEEEEEECCCCCHHCCCCCCCCCCCHHHH
LFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKINDHEVVFYLTRKDASFLSNL
HHHHHHHHCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
ATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAK
HHHHEEEECCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHEEECCCCCCCCCCCE
IDMLVFDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFN
EEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECHHHCCCCCCCCCEEEEEEEC
TQKPPLNDVRVRRALAYAVDKQNILRAVYQNTAIEATGVLPPASWAYDNNKGLVDYNPKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEECCHHH
ARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSDLANIGVKVNIVSYDWSVFSQ
HHHHHHHCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHHH
RLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDSAREVSD
HHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCC
QGECKVIYQQAEAFLAEQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAHTSQAQEEA
CCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCEECCCCCHHHHC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]