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The map label for this gene is sapB [H]

Identifier: 126173848

GI number: 126173848

Start: 1885715

End: 1886746

Strand: Reverse

Name: sapB [H]

Synonym: Sbal_1614

Alternate gene names: 126173848

Gene position: 1886746-1885715 (Counterclockwise)

Preceding gene: 126173849

Following gene: 126173847

Centisome position: 36.8

GC content: 46.61

Gene sequence:

>1032_bases
ATGTTTAAATACCTACTGCGCCGCCTCAATTTGTTTCTTGCTACTTCGTTAGTCATGGTAGGTGTCTTATTTTACGCCAC
GGGCTTATTTCCGGTAGATCGCACCCACGCACTCACTGGCATACATACACCGACTGCGAGCCAACTGGTTCAAATCGAGC
AAGACTACAAATTAGATAAAAACCAAGCATGGCAATTTATCGCTTATCTACAACAAAGGCTTAGTGGTAATTTAGGCATT
TCAGTCACCTCACATCAAGAAGTGGCTGAAGAACTCAGCGCTGTCCTACCCGCCTCCTTCGAACTTGCTGTGATGGCGGC
CATTATCGCGATTTGCTTTGGTGTGCCCTTAGGCGTGCTTGCTTCCCAGAGCCAACATAAGCTCACCCAAAATACCATTA
TGGCGATCACGCTAACAGGTTACTCTGTACCCGTGTTCTGGTTAGGTCTTTATCTTTCGCTCTGGTTTGGCGTCGATCTT
GGTTGGTTACCGATTTCGGGACAAATCAATTTGTTATATGAAATCAAACCTGTCACTGGCTTTATGTTGGTAGATACCCT
GTTGTCAGAGTCTGAATACAGCATGTCGGCATTTAAAGATGCGCTGCTGCACATCATTTTGCCTGCCACGACACTCGCCG
TGTTACCTTTTACTGTGGTGGTTCGCAGCACTCGTTCGGCGATGATGAATGTAATGAATCAAACCTTTATCCGCGCCGCC
GAAGCCAGAGGCATGCATACTAGCACCATCATTTTGCGCCACGCCCTGCCCAATGCCTTGATCCCCGTACTGAAACATTT
AGGGTTGATGCTTGGCTCATTTGCCAGTTATGCCATAGTGGTCGAAATGATTTTCTCTTGGCCTGGCGTGGGTTCTTGGT
TGGTGTCAGGGATTTACCAACGGGACTACACTGTCATCCAAGGTGGTATTTTGGCCGTAGCCCTATTAATTATCTTCCTA
AGTATCTTGATTGAAGTGCTGCATACAGTCTTTAATCCACTGAGCAGAAAAGACCTTTATGCCACCAGTTAA

Upstream 100 bases:

>100_bases
GTGTGGCGTTAACTCGCCATGATGTCAAAGACATGCAACTCACGCCTTTTGGTGGCATTTCCTTCGCCCACACTAGCCAA
GCACAAGAGGAGGCGAATTA

Downstream 100 bases:

>100_bases
AATTTATCAAGAAGATCAGATTGCCTCCCCGACTATGCGGGTTTGGCTTAACTTTTCGGCTAATCCTTTCGCCTTGGCAG
GTCTGTGGACGATTGCTTTC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDKNQAWQFIAYLQQRLSGNLGI
SVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQINLLYEIKPVTGFMLVDTLLSESEYSMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTSTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYATS

Sequences:

>Translated_343_residues
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDKNQAWQFIAYLQQRLSGNLGI
SVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQINLLYEIKPVTGFMLVDTLLSESEYSMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTSTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYATS
>Mature_343_residues
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDKNQAWQFIAYLQQRLSGNLGI
SVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQINLLYEIKPVTGFMLVDTLLSESEYSMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTSTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYATS

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=280, Percent_Identity=41.4285714285714, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=37.4631268436578, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=29.8816568047337, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787761, Length=296, Percent_Identity=37.5, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=28.7390029325513, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787497, Length=337, Percent_Identity=28.7833827893175, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788504, Length=316, Percent_Identity=20.5696202531646, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37837; Mature: 37837

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCH
NQAWQFIAYLQQRLSGNLGISVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVL
HHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDLGWLPISGQINLLYEIKPVTG
CCCHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCHHH
FMLVDTLLSESEYSMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARGMHTSTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQ
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGILAVALLIIFLSILIEVLHTVFNPLSRKDLYATS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCH
NQAWQFIAYLQQRLSGNLGISVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVL
HHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDLGWLPISGQINLLYEIKPVTG
CCCHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCHHH
FMLVDTLLSESEYSMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARGMHTSTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQ
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGILAVALLIIFLSILIEVLHTVFNPLSRKDLYATS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]