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The map label for this gene is sapD [H]

Identifier: 126173846

GI number: 126173846

Start: 1883827

End: 1884834

Strand: Reverse

Name: sapD [H]

Synonym: Sbal_1612

Alternate gene names: 126173846

Gene position: 1884834-1883827 (Counterclockwise)

Preceding gene: 126173847

Following gene: 126173845

Centisome position: 36.76

GC content: 49.8

Gene sequence:

>1008_bases
ATGCCTTTACTCGACGTACGAAATCTCACGATTGAACTCGATACGCCCCACGGTAGAGTGCGGGCGCTCGAAAAAGTTAG
CTTAACGCTCAATGCCGGCGAAATTCATGGCCTAGTCGGTGAGTCAGGCTCTGGACGAAGTTTGTTAGCCAGAGCGATTC
TTGGGATCCCAGGTCCCAACTGGACCATCACAGCCGATCGCATGATGTGGGATGGCAATAACTTGATGGCCATGAGCTCA
AAAGAGCGCCGCAATCTGATGGGTTCAGACATGGCGATGATCTTCCAAGATCCATCGGGCAGCTTAGATCCGGCGCAAAC
CGTCGGCAGTCAGCTGATGCAAGCTATGCCTAAGAATCCCAACGCCTATTTTTGGCAAAAACGTCGACATGCACGGCTGA
CGGCACAAAAGTGGCTACATAAAGTCGGGATCAAGAATCCGAGGCAGGTAATGTCTAGCTACGCCTGGGAATTATCCGAA
GGCGAATGCCAAAAAGTGATGATTGCGATGGCGGTTGCAAACCAGCCTCGCCTCTTGATTGCCGACGAACCCACAAGCTC
GATGGAACTCAGCACTCAAGCGCAGATATTTAGATTATTATCTCAATTAAATCAATTACAAAACGTATCGATTCTATTGA
TCAGCCACGAGCTTGAAACCTTAGCCCAATGGTGCGATCACTTATCCGTGCTCTATTGCGGTCAGGTTATGGAATCAGGG
CCGACAGACGAAGTGATTAAGCAGCCTTATCATCCTTACACTAAGGCGCTGCTTGACAACATGCCCGACTATTCAGGCTC
AGGTGGCCACAAGGCGATTATGCCCACCCTTCCAGGGTCTGCGCCCGCCTTACAGCATTTGCCAATCGGTTGCCGTTTAG
GGCCTCGTTGCCCTGAAGCCCAAAAAAAATGCGTTAATCAGCCAAATTTAAGTCATATTAAAGACCGCTATTTTGCCTGT
CATTTCCCTTATCACGGCGAAACCCACAATGACGATCCCACTGCTTAA

Upstream 100 bases:

>100_bases
TGTGACTATCCCGGGCTTAGCGATTCTTTTCAGTGTGCTTTCCATTAACTTGGTTGGCGATGGCCTACGGTCGGCGCTTG
CGCCCATCAGAAACTAACTT

Downstream 100 bases:

>100_bases
AGTTAACGATCTTTATAAAAGATACGATACCGGTTATCGAGGCTTTTCCCGCCAATATAACGATGCACTAGCGCCCGTAT
CCTTCGAGCTCCAGCGCGGC

Product: oligopeptide/dipeptide ABC transporter ATPase subunit

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPNWTITADRMMWDGNNLMAMSS
KERRNLMGSDMAMIFQDPSGSLDPAQTVGSQLMQAMPKNPNAYFWQKRRHARLTAQKWLHKVGIKNPRQVMSSYAWELSE
GECQKVMIAMAVANQPRLLIADEPTSSMELSTQAQIFRLLSQLNQLQNVSILLISHELETLAQWCDHLSVLYCGQVMESG
PTDEVIKQPYHPYTKALLDNMPDYSGSGGHKAIMPTLPGSAPALQHLPIGCRLGPRCPEAQKKCVNQPNLSHIKDRYFAC
HFPYHGETHNDDPTA

Sequences:

>Translated_335_residues
MPLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPNWTITADRMMWDGNNLMAMSS
KERRNLMGSDMAMIFQDPSGSLDPAQTVGSQLMQAMPKNPNAYFWQKRRHARLTAQKWLHKVGIKNPRQVMSSYAWELSE
GECQKVMIAMAVANQPRLLIADEPTSSMELSTQAQIFRLLSQLNQLQNVSILLISHELETLAQWCDHLSVLYCGQVMESG
PTDEVIKQPYHPYTKALLDNMPDYSGSGGHKAIMPTLPGSAPALQHLPIGCRLGPRCPEAQKKCVNQPNLSHIKDRYFAC
HFPYHGETHNDDPTA
>Mature_334_residues
PLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPNWTITADRMMWDGNNLMAMSSK
ERRNLMGSDMAMIFQDPSGSLDPAQTVGSQLMQAMPKNPNAYFWQKRRHARLTAQKWLHKVGIKNPRQVMSSYAWELSEG
ECQKVMIAMAVANQPRLLIADEPTSSMELSTQAQIFRLLSQLNQLQNVSILLISHELETLAQWCDHLSVLYCGQVMESGP
TDEVIKQPYHPYTKALLDNMPDYSGSGGHKAIMPTLPGSAPALQHLPIGCRLGPRCPEAQKKCVNQPNLSHIKDRYFACH
FPYHGETHNDDPTA

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=328, Percent_Identity=54.8780487804878, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1789963, Length=325, Percent_Identity=39.6923076923077, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1787759, Length=325, Percent_Identity=38.1538461538462, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI48994883, Length=324, Percent_Identity=37.962962962963, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1787500, Length=315, Percent_Identity=33.6507936507937, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI145693107, Length=295, Percent_Identity=33.5593220338983, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1788506, Length=262, Percent_Identity=35.4961832061069, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1789962, Length=307, Percent_Identity=31.2703583061889, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787758, Length=308, Percent_Identity=31.1688311688312, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI48994997, Length=260, Percent_Identity=32.3076923076923, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789890, Length=257, Percent_Identity=31.9066147859922, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789891, Length=224, Percent_Identity=31.25, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787547, Length=261, Percent_Identity=30.2681992337165, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786398, Length=260, Percent_Identity=30, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787792, Length=253, Percent_Identity=31.6205533596838, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789032, Length=238, Percent_Identity=29.4117647058824, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788225, Length=262, Percent_Identity=25.9541984732824, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081834, Length=200, Percent_Identity=32, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081791, Length=267, Percent_Identity=25.0936329588015, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788644, Length=254, Percent_Identity=28.3464566929134, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790162, Length=256, Percent_Identity=23.046875, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786345, Length=227, Percent_Identity=26.431718061674, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786319, Length=225, Percent_Identity=27.1111111111111, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787712, Length=251, Percent_Identity=26.2948207171315, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787370, Length=245, Percent_Identity=25.3061224489796, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789873, Length=225, Percent_Identity=29.3333333333333, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789586, Length=261, Percent_Identity=27.2030651340996, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=232, Percent_Identity=26.7241379310345, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788761, Length=255, Percent_Identity=23.5294117647059, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790525, Length=234, Percent_Identity=29.0598290598291, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790739, Length=246, Percent_Identity=26.0162601626016, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786703, Length=219, Percent_Identity=29.2237442922374, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786803, Length=238, Percent_Identity=23.9495798319328, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48995001, Length=221, Percent_Identity=26.6968325791855, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788210, Length=220, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790190, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787089, Length=237, Percent_Identity=27.0042194092827, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787105, Length=247, Percent_Identity=24.6963562753036, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790544, Length=252, Percent_Identity=25.3968253968254, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=260, Percent_Identity=20.3846153846154, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788897, Length=221, Percent_Identity=28.5067873303167, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789672, Length=247, Percent_Identity=24.6963562753036, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789991, Length=226, Percent_Identity=26.1061946902655, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786253, Length=224, Percent_Identity=26.7857142857143, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788450, Length=245, Percent_Identity=22.4489795918367, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=242, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534520, Length=235, Percent_Identity=27.2340425531915, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=240, Percent_Identity=25.8333333333333, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37225; Mature: 37094

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPN
CCCCCCCCEEEEEECCCHHHHEEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGNNLMAMSSKERRNLMGSDMAMIFQDPSGSLDPAQTVGSQLMQAMPKNP
EEEEECCEEECCCCEEEECCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
NAYFWQKRRHARLTAQKWLHKVGIKNPRQVMSSYAWELSEGECQKVMIAMAVANQPRLLI
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTSSMELSTQAQIFRLLSQLNQLQNVSILLISHELETLAQWCDHLSVLYCGQVMESG
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
PTDEVIKQPYHPYTKALLDNMPDYSGSGGHKAIMPTLPGSAPALQHLPIGCRLGPRCPEA
CCHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCHH
QKKCVNQPNLSHIKDRYFACHFPYHGETHNDDPTA
HHHHCCCCCHHHHCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPN
CCCCCCCEEEEEECCCHHHHEEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGNNLMAMSSKERRNLMGSDMAMIFQDPSGSLDPAQTVGSQLMQAMPKNP
EEEEECCEEECCCCEEEECCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
NAYFWQKRRHARLTAQKWLHKVGIKNPRQVMSSYAWELSEGECQKVMIAMAVANQPRLLI
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTSSMELSTQAQIFRLLSQLNQLQNVSILLISHELETLAQWCDHLSVLYCGQVMESG
ECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
PTDEVIKQPYHPYTKALLDNMPDYSGSGGHKAIMPTLPGSAPALQHLPIGCRLGPRCPEA
CCHHHHHCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCHH
QKKCVNQPNLSHIKDRYFACHFPYHGETHNDDPTA
HHHHCCCCCHHHHCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]