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The map label for this gene is ddc [H]

Identifier: 126173808

GI number: 126173808

Start: 1831801

End: 1833450

Strand: Reverse

Name: ddc [H]

Synonym: Sbal_1574

Alternate gene names: 126173808

Gene position: 1833450-1831801 (Counterclockwise)

Preceding gene: 126173809

Following gene: 126173807

Centisome position: 35.76

GC content: 51.03

Gene sequence:

>1650_bases
ATGACCCAGAAACTCCCTCGCCAAGCCACAGCATCCGAAGAAAGTCTGCTCCGCATTTTTACTGCACCGGAAGATGCAGG
ATCAACGCTGAGTATTATCGAGCAGAAGCTCTCCGAGGACTTAGCAGGCTTTTTGGGTGACAGTATCGCCGCGCTCGAAA
AACCCTTGTCGGAAATTGAAACCGATTTTCAAGCCTTTGAGATCCCAACTCAGCCGCGTTTTGTTTCCGATTACACCGAC
GAAATTATGCAAAATCTGGTGGCGCATTCGGTACACACAGCGGCACCAAGTTTTATCGGCCACATGACGTCGGCACTGCC
CTACTTTGTGTTGCCGCTGTCGAAAATGATGGTGGGACTCAATCAAAATCTGGTCAAAATCGAAACCTCAAAGGCATTTA
CGCCGCTTGAGCGCCAAGTGCTCGGCATGATGCACCATTTGATTTACGACCAAGATACTGATTTTTATCAAAGCTGGATG
CACAGCGCCAATCATTCCCTCGGAGCATTTTGCTCCGGCGGCACGGTTGCCAACATCACCGCCCTGTGGATTGCCCGTAA
CCAATTATTGAAAGCCGATGGTGAGTTTAAAGGCGTCAGCCGCGAAGGCTTACTCAAGGCACTGCGCCACTATGGCTATG
ACGATTTAGCGATTTTGGTCTCCGAGCGAGGTCACTATTCGCTTGGCAAAGCCGTCGATCTGCTTGGTATCGGCCGCGAC
AATATCATCAGCATTCCCACAGGCAGCGATAACAAGGTCGATGTCGCGAAAATGCGCCAAGCCGCCCTTGAACTTGCCCG
TAAAAACATCAAGGTGTTGGCGATTGTTGGTGTGGCTGGCACCACTGAAACCGGTAATGTTGACCCACTGACAGAGTTAG
CGGCGCTCGCAAAAGAGTTAAATTGCCATTTCCATGTGGATGCGGCGTGGGGCGGCGCAAGTTTATTATCCAATAAATAC
CGCCACTTACTCGCTGGTATCGAACTTGCCGATTCAGTCACCATCGATGCCCACAAACAAATGTACGTGCCTATGGGCGC
GGGCATGGTGTTATTTAAAGATCCAGAGTTTGCCCACGCCATTGCCCATCACGCCGAATATATTTTGCGACGTGGTTCAA
AGGACTTAGGCAGCCAAACGCTGGAAGGTTCACGCCCCGGCATGGCGATGTTAGTGCACGCTTGCTTACAGATCATCGGC
CGCGATGGGTATGAAATATTAATTAACAACAGCCTTGAAAAAGCGCGCTATTTTGCAGAGCAAATCAAAGCCCATGAGGA
TTTTGAGCTCGTCACTGAACCAGAACTGTGTCTGCTGACTTATCGTTATGTCCCCGCCCGCGTACAAGCCGCCATGAAGC
TGGCCTGTGAGCAAGCAGACACGATAAGAGTCGCCCGCTTTAACGAGTTGCTCGATGGCCTCACTCAGTTTATTCAAAAG
CACCAACGCGAACAGGGTAAATCCTTCGTCTCCCGCACCCGCATTCAGCCTGCCCGCTACTTTAGGCAAGCGACTGTGGT
GTTTCGCGTAGTACTCGCCAACCCCCTCACCAGCCATGACATTCTCAATCAAGTGCTAATCGAGCAAAGTGAAATCGCCG
CACTAGATAACGAGTTTTTACCCGCACTCATGGCGATGGTTGCCCAATAG

Upstream 100 bases:

>100_bases
ATTGAACATTTTGAGAGTCACTGGTCGAAAGTCACTGGTCCGTTATACTCTTCGAGCAAATTTGCGGTTTCACTATAAAA
ATTAATAGACGGCAAGCCCC

Downstream 100 bases:

>100_bases
CGAGTTGTGAATGATGGAATAGCCCCAATACTATTTGTGGCTATCCCATCATTCGCCGAAATCTGAAGGATTGAACGATT
CGGCGAGATCATTAATCACC

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPTQPRFVSDYTD
EIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWM
HSANHSLGAFCSGGTVANITALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
NIISIPTGSDNKVDVAKMRQAALELARKNIKVLAIVGVAGTTETGNVDPLTELAALAKELNCHFHVDAAWGGASLLSNKY
RHLLAGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIG
RDGYEILINNSLEKARYFAEQIKAHEDFELVTEPELCLLTYRYVPARVQAAMKLACEQADTIRVARFNELLDGLTQFIQK
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLIEQSEIAALDNEFLPALMAMVAQ

Sequences:

>Translated_549_residues
MTQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPTQPRFVSDYTD
EIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWM
HSANHSLGAFCSGGTVANITALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
NIISIPTGSDNKVDVAKMRQAALELARKNIKVLAIVGVAGTTETGNVDPLTELAALAKELNCHFHVDAAWGGASLLSNKY
RHLLAGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIG
RDGYEILINNSLEKARYFAEQIKAHEDFELVTEPELCLLTYRYVPARVQAAMKLACEQADTIRVARFNELLDGLTQFIQK
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLIEQSEIAALDNEFLPALMAMVAQ
>Mature_548_residues
TQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPTQPRFVSDYTDE
IMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWMH
SANHSLGAFCSGGTVANITALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRDN
IISIPTGSDNKVDVAKMRQAALELARKNIKVLAIVGVAGTTETGNVDPLTELAALAKELNCHFHVDAAWGGASLLSNKYR
HLLAGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGR
DGYEILINNSLEKARYFAEQIKAHEDFELVTEPELCLLTYRYVPARVQAAMKLACEQADTIRVARFNELLDGLTQFIQKH
QREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLIEQSEIAALDNEFLPALMAMVAQ

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=376, Percent_Identity=28.4574468085106, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI197276620, Length=477, Percent_Identity=26.8343815513627, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI4503875, Length=477, Percent_Identity=26.8343815513627, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI58331246, Length=472, Percent_Identity=28.3898305084746, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI194294551, Length=378, Percent_Identity=27.5132275132275, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4503281, Length=383, Percent_Identity=20.6266318537859, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI132814448, Length=383, Percent_Identity=20.6266318537859, Blast_Score=70, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555682, Length=476, Percent_Identity=25.8403361344538, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI71993062, Length=460, Percent_Identity=26.0869565217391, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71993058, Length=375, Percent_Identity=27.7333333333333, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17543922, Length=266, Percent_Identity=27.4436090225564, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136594, Length=453, Percent_Identity=28.6975717439294, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24657193, Length=373, Percent_Identity=26.2734584450402, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24657185, Length=373, Percent_Identity=26.2734584450402, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24657188, Length=373, Percent_Identity=26.2734584450402, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI21356415, Length=388, Percent_Identity=23.4536082474227, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585139, Length=249, Percent_Identity=26.9076305220884, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221476190, Length=249, Percent_Identity=26.9076305220884, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24585143, Length=249, Percent_Identity=26.9076305220884, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24652373, Length=244, Percent_Identity=25.8196721311475, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 60729; Mature: 60597

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIE
CCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFQAFEIPTQPRFVSDYTDEIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGL
CCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWMHSANHSLGAFCSGGTVANIT
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEECCCCHHHHH
ALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHEECCCC
NIISIPTGSDNKVDVAKMRQAALELARKNIKVLAIVGVAGTTETGNVDPLTELAALAKEL
CEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
NCHFHVDAAWGGASLLSNKYRHLLAGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCEEEEECCHHHHH
IAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGRDGYEILINNSLEKARYFAE
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
QIKAHEDFELVTEPELCLLTYRYVPARVQAAMKLACEQADTIRVARFNELLDGLTQFIQK
HHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLIEQSEIAALDNEFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
PALMAMVAQ
HHHHHHHCC
>Mature Secondary Structure 
TQKLPRQATASEESLLRIFTAPEDAGSTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIE
CCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFQAFEIPTQPRFVSDYTDEIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGL
CCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQNLVKIETSKAFTPLERQVLGMMHHLIYDQDTDFYQSWMHSANHSLGAFCSGGTVANIT
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEECCCCHHHHH
ALWIARNQLLKADGEFKGVSREGLLKALRHYGYDDLAILVSERGHYSLGKAVDLLGIGRD
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHEECCCC
NIISIPTGSDNKVDVAKMRQAALELARKNIKVLAIVGVAGTTETGNVDPLTELAALAKEL
CEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
NCHFHVDAAWGGASLLSNKYRHLLAGIELADSVTIDAHKQMYVPMGAGMVLFKDPEFAHA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCEEEEECCHHHHH
IAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGRDGYEILINNSLEKARYFAE
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
QIKAHEDFELVTEPELCLLTYRYVPARVQAAMKLACEQADTIRVARFNELLDGLTQFIQK
HHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
HQREQGKSFVSRTRIQPARYFRQATVVFRVVLANPLTSHDILNQVLIEQSEIAALDNEFL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
PALMAMVAQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]