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The map label for this gene is galE [H]

Identifier: 126173720

GI number: 126173720

Start: 1723515

End: 1724528

Strand: Reverse

Name: galE [H]

Synonym: Sbal_1482

Alternate gene names: 126173720

Gene position: 1724528-1723515 (Counterclockwise)

Preceding gene: 126173721

Following gene: 126173719

Centisome position: 33.63

GC content: 46.94

Gene sequence:

>1014_bases
ATGACGATTTTAGTGACTGGCGGTGCTGGCTATATTGGCACTCACACTTTGGTAGAACTGCTCAATGCAGGCAATGACGT
GATTGTGTTAGACAACTTGTCTAATTCGAGCATAGAGGCCTTAAATCGAGTCGAGCGGATCACTGGTAAATCGGTCATTT
TCTATCAAGGCGATATTCTCAATAAAGCCTTATTACAGAAAGTGTTTAACGATCATGCTATCAATTCGGTTATTCACTTT
GCGGGATTAAAAGCTGTGGGTGAATCTGTCGCGAATCCCCTTAAGTATTATGAGAATAACGTCACAGGAACCCTGCTCCT
CTGCCAAGTTATGGCAGAGTTTAAGGTGAAAAATCTCGTTTTCAGCTCATCGGCCACTGTATATGGCGATCCAGCCAGTT
TGCCTATCACCGAAGACTTTCCCACTGGAGCGACCAATCCCTATGGTCAGTCTAAGTTGATGGTTGAACATATACTGGCA
GATGTACACAATGCCGATCCAAGCTGGAATATCGCTCGTCTGCGTTATTTTAATCCGGTCGGCGCCCATGCCAGTGGCTT
AATCGGCGAAGATCCTAACGATATCCCTAACAACTTAATGCCCTTTATTGCGCAGGTTGCCGTGGGTAAACGTGCCGCCT
TAAGCGTGTTTGGTGATGATTATCCGACTCATGATGGGACTGGCGTGCGTGACTATATCCATGTGGTGGATTTAGCCAAT
GGCCATTTAAAAGCACTGGCTAAATTGGCCACTAAACCAGGTCTGGTCACCTATAACTTAGGCACAGGCCAAGGATATAG
TGTTTTAGACATGGTTCATGCCTTTGAAAAAGCCTGTGGTAAGCCTATTGCCTACCAAATTGCGCCACGTCGCCCAGGTG
ATATTGCCGCCTGCTACGCCGATCCAACCCATGCACGGGAAGATCTCGGCTGGCAAGCAACGCATACGCTAGCAGATATG
GCCAACAGTAGCTGGCATTGGCAATCAACCAATCCCAATGGTTATAACGGCTAA

Upstream 100 bases:

>100_bases
AAGGTTACATGCGCGCGAACGTTGAATATGCTCTGCGCCACAGCGAAATCGGTGAAGATTTTGCACAATATTTAAAAACC
GTTGTAAAAGGGATGAAGTA

Downstream 100 bases:

>100_bases
CAAATTGAATGGCTTGTGGAAATATCCCAAGCCATTTTTCTTTATCACTGTGAATACACCCATCACTTTGAATAATTAAC
CGTTCGAGGAGCAATATGAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTILVTGGAGYIGTHTLVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDILNKALLQKVFNDHAINSVIHF
AGLKAVGESVANPLKYYENNVTGTLLLCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DVHNADPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYADPTHAREDLGWQATHTLADM
ANSSWHWQSTNPNGYNG

Sequences:

>Translated_337_residues
MTILVTGGAGYIGTHTLVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDILNKALLQKVFNDHAINSVIHF
AGLKAVGESVANPLKYYENNVTGTLLLCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DVHNADPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYADPTHAREDLGWQATHTLADM
ANSSWHWQSTNPNGYNG
>Mature_336_residues
TILVTGGAGYIGTHTLVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDILNKALLQKVFNDHAINSVIHFA
GLKAVGESVANPLKYYENNVTGTLLLCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILAD
VHNADPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLANG
HLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYADPTHAREDLGWQATHTLADMA
NSSWHWQSTNPNGYNG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=58.5294117647059, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=58.5294117647059, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=58.5294117647059, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI7657641, Length=271, Percent_Identity=26.9372693726937, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI42516563, Length=331, Percent_Identity=24.4712990936556, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=62.202380952381, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI48994969, Length=373, Percent_Identity=27.3458445040214, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=25.3443526170799, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=54.0462427745665, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=53.735632183908, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17568069, Length=341, Percent_Identity=26.3929618768328, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=52.046783625731, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=59.1836734693878, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI21356223, Length=320, Percent_Identity=25.625, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36285; Mature: 36154

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVTGGAGYIGTHTLVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDIL
CEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECHHH
NKALLQKVFNDHAINSVIHFAGLKAVGESVANPLKYYENNVTGTLLLCQVMAEFKVKNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADVHNADPSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCHHHHHHHHHCCC
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYA
CHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
DPTHAREDLGWQATHTLADMANSSWHWQSTNPNGYNG
CCHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
TILVTGGAGYIGTHTLVELLNAGNDVIVLDNLSNSSIEALNRVERITGKSVIFYQGDIL
EEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECHHH
NKALLQKVFNDHAINSVIHFAGLKAVGESVANPLKYYENNVTGTLLLCQVMAEFKVKNLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADVHNADPSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHASGLIGEDPNDIPNNLMPFIAQVAVGKRAALSVFGDDYPTHDGTGVRDYIHVVDLAN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCCCHHHHHHHHHCCC
GHLKALAKLATKPGLVTYNLGTGQGYSVLDMVHAFEKACGKPIAYQIAPRRPGDIAACYA
CHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
DPTHAREDLGWQATHTLADMANSSWHWQSTNPNGYNG
CCHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]