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The map label for this gene is yfcG [H]

Identifier: 126173631

GI number: 126173631

Start: 1603038

End: 1603706

Strand: Reverse

Name: yfcG [H]

Synonym: Sbal_1393

Alternate gene names: 126173631

Gene position: 1603706-1603038 (Counterclockwise)

Preceding gene: 126173632

Following gene: 126173630

Centisome position: 31.28

GC content: 46.19

Gene sequence:

>669_bases
ATGATAGATTTATACACAGCCGCGACCCCTAACGGTTTTAAAATCTCCATCGCACTGGAAGAAATGGGGCTAGAATATCG
CGTCCATAAGCTAGATTTCAGCACCAACGAGCAAAAACAGCCTGAGTTTATTGCTATTAATCCAAATGGCCGAATTCCCG
CTATTATCGACCGCGACAACGAAGATTTTGTGGTATTCGAATCCGGTGCAATTTTGCTGTATCTCGCCGAAAAAACAGGT
AAATTCCTGCCAGCCGATCCTAAAAAGCGCTCACAGGTGATCCAATGGTTAATGTTCCAAATGAGCGGCGTCGGACCCAT
GATGGGTCAAGCTAACGTCTTCTTCCGATACTTCCCTGAGAAAATCCCCGCAGCCATTGACCGTTATCAAAAAGAAGGTC
GACGTTTATTTGAAGTCATGAATACTCAACTCGCCACAAATCAATACCTTGCAGGTGACGAATACACGATTGCCGACATC
GCCACTTGGCCTTGGGTACGTATCCACGAGTGGAGCGGCATCAATATGGAAGGTCTGACCCATTTGCAACGTTGGTTAGA
TGAATTAGCACTCAGACCTGCGTGCCAAAAAGGCATAGTTACGCCGCCACCGGTGGAAATGAGTGATGAAGAACGAGCTA
AACAAATCCAAAAGATGGTGACGAAATAG

Upstream 100 bases:

>100_bases
TCCTGCCATAGTATCGTTAACCCCTAAAAAATAGCGGCACGAATGCCTGAATGGGCCCTAAAGTGAGTAGCTATAAGCGT
TATAACCTAAAGGAATCATC

Downstream 100 bases:

>100_bases
TCATCAGCTAAACGGTCATTGCGCGAATAGCCTTCAAATCGCCGCTAGGTACTGAATACACTATGAGTCTCAGTGACTCA
ACCAAAAAAGCCCCATTAGC

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIDLYTAATPNGFKISIALEEMGLEYRVHKLDFSTNEQKQPEFIAINPNGRIPAIIDRDNEDFVVFESGAILLYLAEKTG
KFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFFRYFPEKIPAAIDRYQKEGRRLFEVMNTQLATNQYLAGDEYTIADI
ATWPWVRIHEWSGINMEGLTHLQRWLDELALRPACQKGIVTPPPVEMSDEERAKQIQKMVTK

Sequences:

>Translated_222_residues
MIDLYTAATPNGFKISIALEEMGLEYRVHKLDFSTNEQKQPEFIAINPNGRIPAIIDRDNEDFVVFESGAILLYLAEKTG
KFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFFRYFPEKIPAAIDRYQKEGRRLFEVMNTQLATNQYLAGDEYTIADI
ATWPWVRIHEWSGINMEGLTHLQRWLDELALRPACQKGIVTPPPVEMSDEERAKQIQKMVTK
>Mature_222_residues
MIDLYTAATPNGFKISIALEEMGLEYRVHKLDFSTNEQKQPEFIAINPNGRIPAIIDRDNEDFVVFESGAILLYLAEKTG
KFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFFRYFPEKIPAAIDRYQKEGRRLFEVMNTQLATNQYLAGDEYTIADI
ATWPWVRIHEWSGINMEGLTHLQRWLDELALRPACQKGIVTPPPVEMSDEERAKQIQKMVTK

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=214, Percent_Identity=44.392523364486, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=41.1214953271028, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI87081789, Length=169, Percent_Identity=32.5443786982249, Blast_Score=84, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324100, Length=232, Percent_Identity=36.2068965517241, Blast_Score=141, Evalue=9e-35,
Organism=Drosophila melanogaster, GI28571670, Length=171, Percent_Identity=33.9181286549708, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17864592, Length=190, Percent_Identity=33.1578947368421, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17933730, Length=191, Percent_Identity=30.8900523560209, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI85725204, Length=192, Percent_Identity=32.8125, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17737923, Length=192, Percent_Identity=32.8125, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI45549270, Length=188, Percent_Identity=30.3191489361702, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646251, Length=187, Percent_Identity=32.0855614973262, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17864596, Length=188, Percent_Identity=28.1914893617021, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864594, Length=192, Percent_Identity=29.6875, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17864598, Length=175, Percent_Identity=32.5714285714286, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646249, Length=157, Percent_Identity=33.1210191082803, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221378983, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646259, Length=192, Percent_Identity=29.6875, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 25514; Mature: 25514

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYTAATPNGFKISIALEEMGLEYRVHKLDFSTNEQKQPEFIAINPNGRIPAIIDRDN
CEEEEECCCCCCEEEEEEHHHCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCEEEECCC
EDFVVFESGAILLYLAEKTGKFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFFRYFPE
CCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCH
KIPAAIDRYQKEGRRLFEVMNTQLATNQYLAGDEYTIADIATWPWVRIHEWSGINMEGLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCEEEEEECCCCCHHHHH
HLQRWLDELALRPACQKGIVTPPPVEMSDEERAKQIQKMVTK
HHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIDLYTAATPNGFKISIALEEMGLEYRVHKLDFSTNEQKQPEFIAINPNGRIPAIIDRDN
CEEEEECCCCCCEEEEEEHHHCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCEEEECCC
EDFVVFESGAILLYLAEKTGKFLPADPKKRSQVIQWLMFQMSGVGPMMGQANVFFRYFPE
CCEEEEECCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCH
KIPAAIDRYQKEGRRLFEVMNTQLATNQYLAGDEYTIADIATWPWVRIHEWSGINMEGLT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEEECCCCEEEEEECCCCCHHHHH
HLQRWLDELALRPACQKGIVTPPPVEMSDEERAKQIQKMVTK
HHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]