Click here to switch to the map view.

The map label for this gene is gpo [H]

Identifier: 126173622

GI number: 126173622

Start: 1591283

End: 1591780

Strand: Reverse

Name: gpo [H]

Synonym: Sbal_1384

Alternate gene names: 126173622

Gene position: 1591780-1591283 (Counterclockwise)

Preceding gene: 126173626

Following gene: 126173620

Centisome position: 31.04

GC content: 40.56

Gene sequence:

>498_bases
ATGGAGGTGAACATGACTACGAATATATACAGCCAATCAGCGACAGACATTCAAGGCAACACAGTAAGTTTAGAGCAGTA
TCGAGGCAAAGTACTCTTGATCGTCAACACCGCCAGTGAATGTGGATTTACGCCGCAATACAAGGGATTAGAAGCGTTAT
ATCAAGAATATAAAGGTCAAGGATTAGTGATTTTGGGCTTTCCTTGCAATCAATTTGGCGCCCAAGAAAAAGCCGATGAA
CAAGGTATTCAAGCCTTTTGTGAATTGAATTTTGGCGTGACATTTCCACTATTTTCTAAAATAGAAGTGAATGGCGAACA
CACCCATCCACTTTATCAATACCTTAAGAAAGCCACTCCCGGTGTATTAGGCACTCAAGGTATCAAATGGAATTTCACCA
AATTTTTAGTTAATCGCCAAGGCGAAGCGATTGAACGATTTGCATCGACCACGAAACCCGAAGCGTTAGAAAGTAAAATT
GCCGCTTTGCTAAAATAA

Upstream 100 bases:

>100_bases
TATATTGATAATTAAGTAAATTAGCAAATCCACAAAATAAATTGCGCACAACTAGATTGCTGGAAATCATTTTTAAGTTT
ATGCTGTTGACTAAGATCCT

Downstream 100 bases:

>100_bases
TTTACTCGCTATCTATTTGAAATTTTGCGTTTTATAAAAATTTAGATTTATTTTAACTTTTTTATGGAACTTTAACCGTA
CAAGCCCCCTCAAATGTATT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MEVNMTTNIYSQSATDIQGNTVSLEQYRGKVLLIVNTASECGFTPQYKGLEALYQEYKGQGLVILGFPCNQFGAQEKADE
QGIQAFCELNFGVTFPLFSKIEVNGEHTHPLYQYLKKATPGVLGTQGIKWNFTKFLVNRQGEAIERFASTTKPEALESKI
AALLK

Sequences:

>Translated_165_residues
MEVNMTTNIYSQSATDIQGNTVSLEQYRGKVLLIVNTASECGFTPQYKGLEALYQEYKGQGLVILGFPCNQFGAQEKADE
QGIQAFCELNFGVTFPLFSKIEVNGEHTHPLYQYLKKATPGVLGTQGIKWNFTKFLVNRQGEAIERFASTTKPEALESKI
AALLK
>Mature_165_residues
MEVNMTTNIYSQSATDIQGNTVSLEQYRGKVLLIVNTASECGFTPQYKGLEALYQEYKGQGLVILGFPCNQFGAQEKADE
QGIQAFCELNFGVTFPLFSKIEVNGEHTHPLYQYLKKATPGVLGTQGIKWNFTKFLVNRQGEAIERFASTTKPEALESKI
AALLK

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=159, Percent_Identity=41.5094339622642, Blast_Score=125, Evalue=1e-29,
Organism=Homo sapiens, GI192455698, Length=159, Percent_Identity=37.1069182389937, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=41.025641025641, Blast_Score=121, Evalue=2e-28,
Organism=Homo sapiens, GI90903240, Length=158, Percent_Identity=40.5063291139241, Blast_Score=120, Evalue=4e-28,
Organism=Homo sapiens, GI4557629, Length=177, Percent_Identity=38.9830508474576, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI90903238, Length=137, Percent_Identity=43.0656934306569, Blast_Score=106, Evalue=8e-24,
Organism=Homo sapiens, GI6006001, Length=181, Percent_Identity=37.0165745856354, Blast_Score=97, Evalue=8e-21,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=36.2637362637363, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI32967607, Length=185, Percent_Identity=32.4324324324324, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI33186887, Length=181, Percent_Identity=33.1491712707182, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1788003, Length=183, Percent_Identity=43.1693989071038, Blast_Score=152, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=159, Percent_Identity=45.9119496855346, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=45.625, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI193210707, Length=170, Percent_Identity=44.1176470588235, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=160, Percent_Identity=41.25, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17550320, Length=175, Percent_Identity=34.2857142857143, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=170, Percent_Identity=32.9411764705882, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI193210709, Length=77, Percent_Identity=46.7532467532467, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71999642, Length=78, Percent_Identity=44.8717948717949, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=97, Percent_Identity=38.1443298969072, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507603, Length=98, Percent_Identity=40.8163265306122, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=53.75, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=52.8301886792453, Blast_Score=187, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=49.0322580645161, Blast_Score=161, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24656767, Length=174, Percent_Identity=45.4022988505747, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=47.7987421383648, Blast_Score=146, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=47.7987421383648, Blast_Score=146, Evalue=5e-36,
Organism=Drosophila melanogaster, GI85726443, Length=165, Percent_Identity=40.6060606060606, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18338; Mature: 18338

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVNMTTNIYSQSATDIQGNTVSLEQYRGKVLLIVNTASECGFTPQYKGLEALYQEYKGQ
CCCCCCCCCCCCCCCCCCCCEEEHHHHCCEEEEEEECHHHCCCCCCCCCHHHHHHHHCCC
GLVILGFPCNQFGAQEKADEQGIQAFCELNFGVTFPLFSKIEVNGEHTHPLYQYLKKATP
EEEEECCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
GVLGTQGIKWNFTKFLVNRQGEAIERFASTTKPEALESKIAALLK
CCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MEVNMTTNIYSQSATDIQGNTVSLEQYRGKVLLIVNTASECGFTPQYKGLEALYQEYKGQ
CCCCCCCCCCCCCCCCCCCCEEEHHHHCCEEEEEEECHHHCCCCCCCCCHHHHHHHHCCC
GLVILGFPCNQFGAQEKADEQGIQAFCELNFGVTFPLFSKIEVNGEHTHPLYQYLKKATP
EEEEECCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
GVLGTQGIKWNFTKFLVNRQGEAIERFASTTKPEALESKIAALLK
CCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]