Click here to switch to the map view.

The map label for this gene is mntH [H]

Identifier: 125624296

GI number: 125624296

Start: 1462457

End: 1463989

Strand: Reverse

Name: mntH [H]

Synonym: llmg_1490

Alternate gene names: 125624296

Gene position: 1463989-1462457 (Counterclockwise)

Preceding gene: 125624297

Following gene: 125624295

Centisome position: 57.88

GC content: 36.33

Gene sequence:

>1533_bases
ATGAATGATAAAGAACATCAACGACATCGATTGATTTATCATACGAATGGAAAATCCTTAGAGGAAATAAATGGGACAGT
AGAAGTGCCTAAAAATGTTGGTTTTTTCAAAATGTTGTTGACTTACTCAGGACCAGGTGCACTGGTCGCGGTTGGTTACA
TGGACCCTGGGAATTGGTCAACGTCAATTACTGGAGGGCAGAACTTTCAATACTTACTGATTTCGGTTATTCTGATGTCC
AGTCTGATTGCAATGCTCCTTCAGTATATGTCAGCAAAATTAGGAATTGTCAGCCAGATGGATTTAGCTCAGGCTATCAG
GGCGCGCACCAGCAAGACTCTGGGTATTGTTTTATGGATTTTAACTGAACTGGCAATCATGGCTACTGATATTGCTGAAG
TCATCGGTGCGGCTATTGCCTTATATCTTCTGTTTAATATTCCGTTAATATTAGCTGTTTTTATCACAGTCCTTGATGTC
TTTTTGCTTTTATTACTGACAAGAATTGGTTTCCGTAAGATTGAAGCCTTGGTTATTTGTTTGATTCTAGTTATTCTAGC
AATATTTGCTTATCAAGTTGCTTTATCCAATCCAGATTGGAAAGGAATTATTGAGGGATTTATTCCTAATAATCGAACTT
TTGCTTCCTCACCAACAGTAGCGGGGATGTCGCCTTTAACAGGCGCATTAGGAATTATTGGCGCTACGGTTATGCCTCAT
AATTTATATCTTCATTCTTCTATTTCACAAAGTAGAAAAATTAATCATCAAGATAAAAGTGATGTTGCCAGAGCAGTAAG
ATTCTCGACATGGGACTCTAATATTCAGCTGACAGTCGCTTTTGTTGTAAATTCTCTTTTACTAATTATGGGTGTAGCGG
TCTTTAAAACAGGAGTAATTGATGATCCGTCATTCTTTGGTTTATACGATGCATTATCTAACCCTTCGGTTTTAAGTAAT
GGTCTTCTTGCAGACGTTGCAAAAACGGGTGCACTTTCAACCTTATTTGCCGTGGCTCTCCTTGCTTCTGGACAAAACTC
AACCATTACTGGAACTTTAACAGGACAGGTTATTATGGAAGGATTTATTCATATGAGAATGCCAATGTGGGCAAGAAGGT
TGGTAACTCGCCTGCTATCGGTAGTTCCTGTCTTGATTTGTGTCTCTATGACTAGAGGACAAACTTTGAAAGCTCAACAT
GAAGCAATAAATAATTTGATGAATAATTCTCAAGTTTTTCTAGCTTTTGCCCTTCCTTTTTCGATTATTCCATTGTTAAT
GCTAACTAATAGCAAGGAAGAAATGGGTGATTTTAAAAATAATTTAATCATTAAATTTTTAGGTTGGATTTCAGTTATTG
CCTTGACTTATCTCAATTTAATTGGCTTACCAAATCAGATTGATAGTTTTCTTCCGAATAATCTAAGCTTGTCTCATTTT
ATTGCCGGTTTATTGATTGTTGGAGTTATCATTTTATTAATCTGGTCGATTTTTGAACTTCATCGTGGAAATAAAAAACT
CTATTTAAAATAG

Upstream 100 bases:

>100_bases
GATAATTTTTTAATCGATAACTGATGCATTAAATTACTATAAAAATATACTTAACTATAAAGGGTGCTGAATTTTATTCA
GCTTAGAATTTGGAGAAATA

Downstream 100 bases:

>100_bases
AGTTTTTCTTTATATAGGTAGGGTGTGATTTAAATTAAAATATGAAATGTGCTATAATGTAAGAAAATGATTAATGGAGA
TTATGTATTTGACTAAAAAT

Product: putative proton-dependent manganese transporter group C beta

Products: NA

Alternate protein names: Hop-inducible cation transporter [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MNDKEHQRHRLIYHTNGKSLEEINGTVEVPKNVGFFKMLLTYSGPGALVAVGYMDPGNWSTSITGGQNFQYLLISVILMS
SLIAMLLQYMSAKLGIVSQMDLAQAIRARTSKTLGIVLWILTELAIMATDIAEVIGAAIALYLLFNIPLILAVFITVLDV
FLLLLLTRIGFRKIEALVICLILVILAIFAYQVALSNPDWKGIIEGFIPNNRTFASSPTVAGMSPLTGALGIIGATVMPH
NLYLHSSISQSRKINHQDKSDVARAVRFSTWDSNIQLTVAFVVNSLLLIMGVAVFKTGVIDDPSFFGLYDALSNPSVLSN
GLLADVAKTGALSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRMPMWARRLVTRLLSVVPVLICVSMTRGQTLKAQH
EAINNLMNNSQVFLAFALPFSIIPLLMLTNSKEEMGDFKNNLIIKFLGWISVIALTYLNLIGLPNQIDSFLPNNLSLSHF
IAGLLIVGVIILLIWSIFELHRGNKKLYLK

Sequences:

>Translated_510_residues
MNDKEHQRHRLIYHTNGKSLEEINGTVEVPKNVGFFKMLLTYSGPGALVAVGYMDPGNWSTSITGGQNFQYLLISVILMS
SLIAMLLQYMSAKLGIVSQMDLAQAIRARTSKTLGIVLWILTELAIMATDIAEVIGAAIALYLLFNIPLILAVFITVLDV
FLLLLLTRIGFRKIEALVICLILVILAIFAYQVALSNPDWKGIIEGFIPNNRTFASSPTVAGMSPLTGALGIIGATVMPH
NLYLHSSISQSRKINHQDKSDVARAVRFSTWDSNIQLTVAFVVNSLLLIMGVAVFKTGVIDDPSFFGLYDALSNPSVLSN
GLLADVAKTGALSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRMPMWARRLVTRLLSVVPVLICVSMTRGQTLKAQH
EAINNLMNNSQVFLAFALPFSIIPLLMLTNSKEEMGDFKNNLIIKFLGWISVIALTYLNLIGLPNQIDSFLPNNLSLSHF
IAGLLIVGVIILLIWSIFELHRGNKKLYLK
>Mature_510_residues
MNDKEHQRHRLIYHTNGKSLEEINGTVEVPKNVGFFKMLLTYSGPGALVAVGYMDPGNWSTSITGGQNFQYLLISVILMS
SLIAMLLQYMSAKLGIVSQMDLAQAIRARTSKTLGIVLWILTELAIMATDIAEVIGAAIALYLLFNIPLILAVFITVLDV
FLLLLLTRIGFRKIEALVICLILVILAIFAYQVALSNPDWKGIIEGFIPNNRTFASSPTVAGMSPLTGALGIIGATVMPH
NLYLHSSISQSRKINHQDKSDVARAVRFSTWDSNIQLTVAFVVNSLLLIMGVAVFKTGVIDDPSFFGLYDALSNPSVLSN
GLLADVAKTGALSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRMPMWARRLVTRLLSVVPVLICVSMTRGQTLKAQH
EAINNLMNNSQVFLAFALPFSIIPLLMLTNSKEEMGDFKNNLIIKFLGWISVIALTYLNLIGLPNQIDSFLPNNLSLSHF
IAGLLIVGVIILLIWSIFELHRGNKKLYLK

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=425, Percent_Identity=31.7647058823529, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI295293178, Length=449, Percent_Identity=32.0712694877506, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI295293167, Length=449, Percent_Identity=32.0712694877506, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI295293175, Length=449, Percent_Identity=32.0712694877506, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI295293173, Length=449, Percent_Identity=32.0712694877506, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI10835169, Length=449, Percent_Identity=32.0712694877506, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI295293171, Length=449, Percent_Identity=32.0712694877506, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI295293169, Length=449, Percent_Identity=32.0712694877506, Blast_Score=214, Evalue=2e-55,
Organism=Escherichia coli, GI1788736, Length=442, Percent_Identity=33.2579185520362, Blast_Score=228, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI193210616, Length=474, Percent_Identity=32.2784810126582, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17569473, Length=398, Percent_Identity=33.9195979899498, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71999499, Length=443, Percent_Identity=33.1828442437923, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71993856, Length=278, Percent_Identity=34.5323741007194, Blast_Score=163, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324450, Length=444, Percent_Identity=31.981981981982, Blast_Score=219, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6323062, Length=431, Percent_Identity=34.8027842227378, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6321841, Length=466, Percent_Identity=34.3347639484979, Blast_Score=206, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24648607, Length=509, Percent_Identity=31.041257367387, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI281362176, Length=509, Percent_Identity=31.041257367387, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24648609, Length=509, Percent_Identity=31.041257367387, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI45553443, Length=436, Percent_Identity=32.7981651376147, Blast_Score=238, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 55862; Mature: 55862

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKEHQRHRLIYHTNGKSLEEINGTVEVPKNVGFFKMLLTYSGPGALVAVGYMDPGNWS
CCCCCCCCCEEEEECCCCCHHHCCCCEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCC
TSITGGQNFQYLLISVILMSSLIAMLLQYMSAKLGIVSQMDLAQAIRARTSKTLGIVLWI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LTELAIMATDIAEVIGAAIALYLLFNIPLILAVFITVLDVFLLLLLTRIGFRKIEALVIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILVILAIFAYQVALSNPDWKGIIEGFIPNNRTFASSPTVAGMSPLTGALGIIGATVMPH
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
NLYLHSSISQSRKINHQDKSDVARAVRFSTWDSNIQLTVAFVVNSLLLIMGVAVFKTGVI
CEEEECCHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
DDPSFFGLYDALSNPSVLSNGLLADVAKTGALSTLFAVALLASGQNSTITGTLTGQVIME
CCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
GFIHMRMPMWARRLVTRLLSVVPVLICVSMTRGQTLKAQHEAINNLMNNSQVFLAFALPF
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHH
SIIPLLMLTNSKEEMGDFKNNLIIKFLGWISVIALTYLNLIGLPNQIDSFLPNNLSLSHF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
IAGLLIVGVIILLIWSIFELHRGNKKLYLK
HHHHHHHHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MNDKEHQRHRLIYHTNGKSLEEINGTVEVPKNVGFFKMLLTYSGPGALVAVGYMDPGNWS
CCCCCCCCCEEEEECCCCCHHHCCCCEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCC
TSITGGQNFQYLLISVILMSSLIAMLLQYMSAKLGIVSQMDLAQAIRARTSKTLGIVLWI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
LTELAIMATDIAEVIGAAIALYLLFNIPLILAVFITVLDVFLLLLLTRIGFRKIEALVIC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILVILAIFAYQVALSNPDWKGIIEGFIPNNRTFASSPTVAGMSPLTGALGIIGATVMPH
HHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
NLYLHSSISQSRKINHQDKSDVARAVRFSTWDSNIQLTVAFVVNSLLLIMGVAVFKTGVI
CEEEECCHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCC
DDPSFFGLYDALSNPSVLSNGLLADVAKTGALSTLFAVALLASGQNSTITGTLTGQVIME
CCCCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
GFIHMRMPMWARRLVTRLLSVVPVLICVSMTRGQTLKAQHEAINNLMNNSQVFLAFALPF
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHH
SIIPLLMLTNSKEEMGDFKNNLIIKFLGWISVIALTYLNLIGLPNQIDSFLPNNLSLSHF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
IAGLLIVGVIILLIWSIFELHRGNKKLYLK
HHHHHHHHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11414327 [H]