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The map label for this gene is frdC [H]

Identifier: 125624250

GI number: 125624250

Start: 1407163

End: 1408671

Strand: Reverse

Name: frdC [H]

Synonym: llmg_1441

Alternate gene names: 125624250

Gene position: 1408671-1407163 (Counterclockwise)

Preceding gene: 125624251

Following gene: 125624249

Centisome position: 55.69

GC content: 37.91

Gene sequence:

>1509_bases
ATGAAAATTTGGACAAAACTGGGCTTGCTCTCGCTTGTAGGCCTCACTTTAACAGCTTGTGGAAGCAACACAAAGACAGC
TAAAGAACAATCGAGTTCGTCTCAAAAAGTTGAAACTTCTGCTGGTGCAAGTAAATCAAACACTTATGCAGACCCTTCAA
CATTAAGTGATAAATATGATGTTATTATTGTCGGTTCAGGCGGAGCTGGAATGACAGCAGCAATCGAAGCGAAAGATGCT
GGAATGAATCCAGTGATTTTGGAAAAAATGCCGATAGCTGGAGGAAATACTTCAAAAGCCTCAGCTGGTTTGAACGCATC
AGAAACATCAGTCGAAAAAGCACAGGGTGTTGCCGATTCAAATGATAAATTTTATGAAGAAACGCTCAAAGGTGGTGGTG
GAACCAATGATAAAGCCCTTCTTCGCTATTTTGTTGACCATTCAGCTGGAGCTGTCGATTGGTTAAATACCAATGGAATT
GTATTAGATAATTTAACAACTACAGGTGGGATGTCAGTCTCTAGAACTCACCGTCCACATGATGGTTCAGCAGTAGGGGG
CTATCTGGTAAAAGGACTCGAAGAAAACATCTCTAAACGAAATATTCCATTATTTGTAAATAGTGATGTAACTAAAATTA
CTGAAAAAGATGGAAAAGTATCTGGAGTAAAGGTTAAAATCGAAGGGGAAACAAAAAATATTTCTTCTAAGGCAGTAGTA
GTCACAACTGGAGGCTTTGGTGCAAACAAAAAAATGATTGCCAAATATCGTCCAGATTTAAAAGATTATGTAACAACAAA
TGCTGCTGGTTCAACTGGTGACGGAATCACTATGATTTCAGAACTTGGTGGTCAATTAGTTGATATGGATAAAATCCAAA
TTCACCCAACTGTATTCCAAAAAACAGGTTATCTGGTTTCAGAGTCTATCCGTGGTGAGGGAGCAATTCTTGTAAATCAA
AAAGGAAAACGTTTCTTTAATGAAATGGATACCCGTGATAAAGTATCTGCTGCTGAACTCAAACAACCTGGGAAATATTC
TTATGTTATTTTCGGTGAAGGAACAAAAGCTAATGTAAAAGCTGTTGAACAATATATGTCTAAAGATATGGTTGTAGAAG
GAAATAGTGTAAAAGATCTTGCTGACAAGCTTGATATTGACCAAAAAACACTCACTTCAACAATTGATGGCTGGAACAAA
GCAGTTTCAACTAAAAAAGATGAAGAATTTGGTCGTACAACAGGAATGACCAATAATATTTCTGGTAAGTTTTATGCGAT
TAAAGTAGCGCCGGGTATTCACCATACAATGGCAGGCGTTAAAATTAATACAAATACTCAAGTTCTGAAAAAAGATGGAA
GTCCAATCCAAGGCTTATATGCTGCAGGAGAAGTTACTGGTGGCCTCCATGGTGGAAATCGAATTGGTGGAAATGCAGTC
GCTGATATTGTAATATTTGGACGTCAAGCAGGGCTTCAATCATCTGCTTACGCGAAAATAATTGACTAA

Upstream 100 bases:

>100_bases
ATTTTTTATTTAATGATACCTAAAAATTTTATAGATATTTGGATAGTTTCCAAAAATTTGTTATAATCGATATGTGAATT
TTAACACAAAAGGAGTAACT

Downstream 100 bases:

>100_bases
TATTAAAGAAAGTTAAAATTAAACTGGAATGAAGTGCTGACAAGTCTGTCAGTACTTTTTTCTAAAATAATGCTAATTTA
CATTTTTATAGTATACTAAT

Product: fumarate reductase flavoprotein subunit

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKIWTKLGLLSLVGLTLTACGSNTKTAKEQSSSSQKVETSAGASKSNTYADPSTLSDKYDVIIVGSGGAGMTAAIEAKDA
GMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADSNDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGI
VLDNLTTTGGMSVSRTHRPHDGSAVGGYLVKGLEENISKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKNISSKAVV
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGQLVDMDKIQIHPTVFQKTGYLVSESIRGEGAILVNQ
KGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKANVKAVEQYMSKDMVVEGNSVKDLADKLDIDQKTLTSTIDGWNK
AVSTKKDEEFGRTTGMTNNISGKFYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
ADIVIFGRQAGLQSSAYAKIID

Sequences:

>Translated_502_residues
MKIWTKLGLLSLVGLTLTACGSNTKTAKEQSSSSQKVETSAGASKSNTYADPSTLSDKYDVIIVGSGGAGMTAAIEAKDA
GMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADSNDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGI
VLDNLTTTGGMSVSRTHRPHDGSAVGGYLVKGLEENISKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKNISSKAVV
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGQLVDMDKIQIHPTVFQKTGYLVSESIRGEGAILVNQ
KGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKANVKAVEQYMSKDMVVEGNSVKDLADKLDIDQKTLTSTIDGWNK
AVSTKKDEEFGRTTGMTNNISGKFYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
ADIVIFGRQAGLQSSAYAKIID
>Mature_502_residues
MKIWTKLGLLSLVGLTLTACGSNTKTAKEQSSSSQKVETSAGASKSNTYADPSTLSDKYDVIIVGSGGAGMTAAIEAKDA
GMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADSNDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGI
VLDNLTTTGGMSVSRTHRPHDGSAVGGYLVKGLEENISKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKNISSKAVV
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGQLVDMDKIQIHPTVFQKTGYLVSESIRGEGAILVNQ
KGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKANVKAVEQYMSKDMVVEGNSVKDLADKLDIDQKTLTSTIDGWNK
AVSTKKDEEFGRTTGMTNNISGKFYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
ADIVIFGRQAGLQSSAYAKIID

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=456, Percent_Identity=24.780701754386, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1790597, Length=403, Percent_Identity=28.287841191067, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788928, Length=462, Percent_Identity=25.974025974026, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786942, Length=289, Percent_Identity=29.757785467128, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71986328, Length=461, Percent_Identity=33.1887201735358, Blast_Score=243, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17505833, Length=443, Percent_Identity=26.1851015801354, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17550100, Length=434, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320788, Length=459, Percent_Identity=35.7298474945534, Blast_Score=240, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6322511, Length=465, Percent_Identity=33.5483870967742, Blast_Score=226, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6322701, Length=458, Percent_Identity=24.0174672489083, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322416, Length=475, Percent_Identity=24.6315789473684, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17137288, Length=457, Percent_Identity=26.4770240700219, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655642, Length=457, Percent_Identity=26.4770240700219, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24655647, Length=457, Percent_Identity=26.4770240700219, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 52934; Mature: 52934

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIWTKLGLLSLVGLTLTACGSNTKTAKEQSSSSQKVETSAGASKSNTYADPSTLSDKYD
CCHHHHHHHHHHHHHHHEECCCCCCCHHHHCCCCCCEEHHCCCCCCCCCCCCCCCCCCCC
VIIVGSGGAGMTAAIEAKDAGMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADS
EEEEECCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
NDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGIVLDNLTTTGGMSVSRTHRPH
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCEECCCCCCC
DGSAVGGYLVKGLEENISKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKNISSKAVV
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCEEEEEEEEECCCCCCCCCEEE
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGQLVDMDKIQIHPTVFQ
EEECCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCEEECCEEEECCCHHH
KTGYLVSESIRGEGAILVNQKGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKANVK
HCCCEEECCCCCCCEEEECCCCHHHHHHCCCCCCCCHHHHCCCCCEEEEEEECCCCCHHH
AVEQYMSKDMVVEGNSVKDLADKLDIDQKTLTSTIDGWNKAVSTKKDEEFGRTTGMTNNI
HHHHHHCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCC
SGKFYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
CCEEEEEEECCCCCHHHCCCEECCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCE
ADIVIFGRQAGLQSSAYAKIID
EEEEEEECCCCCCCCCEEEECC
>Mature Secondary Structure
MKIWTKLGLLSLVGLTLTACGSNTKTAKEQSSSSQKVETSAGASKSNTYADPSTLSDKYD
CCHHHHHHHHHHHHHHHEECCCCCCCHHHHCCCCCCEEHHCCCCCCCCCCCCCCCCCCCC
VIIVGSGGAGMTAAIEAKDAGMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADS
EEEEECCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
NDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGIVLDNLTTTGGMSVSRTHRPH
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCEECCCCCCC
DGSAVGGYLVKGLEENISKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKNISSKAVV
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCEEEEEEEEECCCCCCCCCEEE
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGQLVDMDKIQIHPTVFQ
EEECCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCEEECCEEEECCCHHH
KTGYLVSESIRGEGAILVNQKGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKANVK
HCCCEEECCCCCCCEEEECCCCHHHHHHCCCCCCCCHHHHCCCCCEEEEEEECCCCCHHH
AVEQYMSKDMVVEGNSVKDLADKLDIDQKTLTSTIDGWNKAVSTKKDEEFGRTTGMTNNI
HHHHHHCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCC
SGKFYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
CCEEEEEEECCCCCHHHCCCEECCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCE
ADIVIFGRQAGLQSSAYAKIID
EEEEEEECCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]