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The map label for this gene is arsC [H]

Identifier: 124485641

GI number: 124485641

Start: 796906

End: 797283

Strand: Reverse

Name: arsC [H]

Synonym: Mlab_0819

Alternate gene names: 124485641

Gene position: 797283-796906 (Counterclockwise)

Preceding gene: 124485642

Following gene: 124485640

Centisome position: 44.17

GC content: 56.08

Gene sequence:

>378_bases
ATGAAGCGGGTCGCCTTTCTCTGCATCAAAAACTCCTGCAGATCCCAGATCGCAGAAGCGCTCTGTCGGCATTTCACAGG
GGACAGGTTCGCCTGCTTCTCGGCAGGCAGCGAGCCGGGAGACAAGGTCGATCCGACAGCCGTCCGTCTTATGCAGGAGA
TCTACGGGATCGATCTTGCAAAAATGCGGCCGAAACACATCTCCGACCTGCCGGATATCGACATAATCGTCACGATGGGA
TGCGGGGTCGCCTGTCCCGTGATCCCCGGGGTAAAGCGGATCGCATGGCAGATCGACGACCCGGTCGGCAAAGGAGATGA
GGCATATTTCCAGGCGATCGCCGAGATCGAAGCAAAGATAAAATCATTGAAAGAGTGA

Upstream 100 bases:

>100_bases
CCATGCTTTCGGCGATATTCAAAAAACAGTTCGTGATGGTTTTTGTTGCGACGATCTTTCTTGCGGCCGTGCTGACGGGA
ATTACTGTCCAGGTGATCGT

Downstream 100 bases:

>100_bases
TGCTATGACAAAAAACAATTCTGCAGGTCTTGGGATGTTCGGCAAATACCTCACCCTCTGGGTGATCATCTGCATGATCG
TCGGTGTTCTGATCGGCAGG

Product: radical SAM family protein

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKRVAFLCIKNSCRSQIAEALCRHFTGDRFACFSAGSEPGDKVDPTAVRLMQEIYGIDLAKMRPKHISDLPDIDIIVTMG
CGVACPVIPGVKRIAWQIDDPVGKGDEAYFQAIAEIEAKIKSLKE

Sequences:

>Translated_125_residues
MKRVAFLCIKNSCRSQIAEALCRHFTGDRFACFSAGSEPGDKVDPTAVRLMQEIYGIDLAKMRPKHISDLPDIDIIVTMG
CGVACPVIPGVKRIAWQIDDPVGKGDEAYFQAIAEIEAKIKSLKE
>Mature_125_residues
MKRVAFLCIKNSCRSQIAEALCRHFTGDRFACFSAGSEPGDKVDPTAVRLMQEIYGIDLAKMRPKHISDLPDIDIIVTMG
CGVACPVIPGVKRIAWQIDDPVGKGDEAYFQAIAEIEAKIKSLKE

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 13740; Mature: 13740

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVAFLCIKNSCRSQIAEALCRHFTGDRFACFSAGSEPGDKVDPTAVRLMQEIYGIDLA
CCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHH
KMRPKHISDLPDIDIIVTMGCGVACPVIPGVKRIAWQIDDPVGKGDEAYFQAIAEIEAKI
HCCCHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
KSLKE
HHHCC
>Mature Secondary Structure
MKRVAFLCIKNSCRSQIAEALCRHFTGDRFACFSAGSEPGDKVDPTAVRLMQEIYGIDLA
CCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCHH
KMRPKHISDLPDIDIIVTMGCGVACPVIPGVKRIAWQIDDPVGKGDEAYFQAIAEIEAKI
HCCCHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
KSLKE
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA