Click here to switch to the map view.

The map label for this gene is yleA [C]

Identifier: 124485405

GI number: 124485405

Start: 550528

End: 551778

Strand: Reverse

Name: yleA [C]

Synonym: Mlab_0580

Alternate gene names: 124485405

Gene position: 551778-550528 (Counterclockwise)

Preceding gene: 124485411

Following gene: 124485381

Centisome position: 30.57

GC content: 53.72

Gene sequence:

>1251_bases
ATGGACGCAGAAACCGCCGAGTCGCTGAAGCTTCTCAAAAATATATCCCTCTATACGGAAACCTACGGGTGTACCTACAA
TGCGGGAGATACCGAGAAACTGATGGAGATCGCCAGAAATCAGGGATGTGTTCCGGCATCGTCCGCAGAGGAAGCGGACG
CAATACTCATTAATACCTGCGTGGTGATCGACAAAACCGAGCAGCACATGTATGAACGTCTCGATTTATACGCGGGCAAA
CTCCTTTTCGTCACCGGGTGTCTGCCGCCGGTCGCCGCGGACGTGCTCCGCACACGGTACCCCAAGATCCATATCATCGA
CCCTGCCCTTATCCATTCCTGCTATATGGAGGTCGGAACGGCTCATGTTGGAACAAATGCCGTCCTCCAGATCGCCAGGG
GATGCAATGGGCACTGTACGTACTGCATCACGCGGCTCGCACGGGGAAAGCTGGTAAGTTTTTCAGCCGAAGACATCGTT
CGTCAGGCAAAAAGTATCGTTGAAGCGGGAGCAACCGAAATCCAGCTGACGGCACAGGATACATCGTCGTGGGGCCTCGA
CCGAAACGACGGTCTGAGACTCCCGGATCTTTTACGGCAGCTCTGCGCGATCCCCGGTAATTTCATGATCCGGATCGGGA
TGGCAAATCCCGATACGCTTCTCCCGATCCTCGATGATTTTCTTGACGCACTCAAAGACCCAAAGATATTTCTGTTTCTG
CACATCCCGGTCCAGTCGGGATCGGATTCGGTCCTCAGGCTGATGGGGCGGCGCTACACCTCGGCCCAGTATGAAGAGAT
CTGTCAAAGGGCACGCAAAGCGTTCCCGGAGATCAGAATAAGTACCGATTATATCGCGGGATTTTCCGGCGAAACGGATG
AAGACGCTGCAAAGTCCGCAGAACAGATCAGGCGGACAAGACCCGGAAAGGTGAACATCACGCGTTTTTCCGTTCGCCCG
AACACGCCGGCCGCTAAGATGAAAAAAATCCCGGAACCGATCAAAAAGCAGAGGTCGCGGGAGCTTACCGATGCGGCAAA
CGAGGTGTATGACGCCAATAACGAAGCACTGATCGGCCATATCATGACGGCTGTCGTGACGGAAGTGGTAAAAGCAGGAA
GTGTTACGGCGCGTGACAGGACCTATCAGAATATTGTTATCATGGAAAATCTCGAGATCGGAACCGAGATAACGGTAAAG
ATAACCGGACACCGCCGCCATTATCTGATCGGCGAACGGATCGTGCCCTGA

Upstream 100 bases:

>100_bases
ACCGGATTTCTGTATCTTTCCCATATGGATTCTCCCGTTCTAAAAGATAGTTGGAATACTATTTAATTATTTATCTGTGG
GCAGATATAGTAAGGTATAC

Downstream 100 bases:

>100_bases
GCTCTCTAACTATACTATTTTAGAGGAGTTACGCGGTGTTAGTCTCAATCGAATCCGGAAGGAGTCTGTTGAGTGTGGAG
ACAAGAGATTATTTTACCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDAETAESLKLLKNISLYTETYGCTYNAGDTEKLMEIARNQGCVPASSAEEADAILINTCVVIDKTEQHMYERLDLYAGK
LLFVTGCLPPVAADVLRTRYPKIHIIDPALIHSCYMEVGTAHVGTNAVLQIARGCNGHCTYCITRLARGKLVSFSAEDIV
RQAKSIVEAGATEIQLTAQDTSSWGLDRNDGLRLPDLLRQLCAIPGNFMIRIGMANPDTLLPILDDFLDALKDPKIFLFL
HIPVQSGSDSVLRLMGRRYTSAQYEEICQRARKAFPEIRISTDYIAGFSGETDEDAAKSAEQIRRTRPGKVNITRFSVRP
NTPAAKMKKIPEPIKKQRSRELTDAANEVYDANNEALIGHIMTAVVTEVVKAGSVTARDRTYQNIVIMENLEIGTEITVK
ITGHRRHYLIGERIVP

Sequences:

>Translated_416_residues
MDAETAESLKLLKNISLYTETYGCTYNAGDTEKLMEIARNQGCVPASSAEEADAILINTCVVIDKTEQHMYERLDLYAGK
LLFVTGCLPPVAADVLRTRYPKIHIIDPALIHSCYMEVGTAHVGTNAVLQIARGCNGHCTYCITRLARGKLVSFSAEDIV
RQAKSIVEAGATEIQLTAQDTSSWGLDRNDGLRLPDLLRQLCAIPGNFMIRIGMANPDTLLPILDDFLDALKDPKIFLFL
HIPVQSGSDSVLRLMGRRYTSAQYEEICQRARKAFPEIRISTDYIAGFSGETDEDAAKSAEQIRRTRPGKVNITRFSVRP
NTPAAKMKKIPEPIKKQRSRELTDAANEVYDANNEALIGHIMTAVVTEVVKAGSVTARDRTYQNIVIMENLEIGTEITVK
ITGHRRHYLIGERIVP
>Mature_416_residues
MDAETAESLKLLKNISLYTETYGCTYNAGDTEKLMEIARNQGCVPASSAEEADAILINTCVVIDKTEQHMYERLDLYAGK
LLFVTGCLPPVAADVLRTRYPKIHIIDPALIHSCYMEVGTAHVGTNAVLQIARGCNGHCTYCITRLARGKLVSFSAEDIV
RQAKSIVEAGATEIQLTAQDTSSWGLDRNDGLRLPDLLRQLCAIPGNFMIRIGMANPDTLLPILDDFLDALKDPKIFLFL
HIPVQSGSDSVLRLMGRRYTSAQYEEICQRARKAFPEIRISTDYIAGFSGETDEDAAKSAEQIRRTRPGKVNITRFSVRP
NTPAAKMKKIPEPIKKQRSRELTDAANEVYDANNEALIGHIMTAVVTEVVKAGSVTARDRTYQNIVIMENLEIGTEITVK
ITGHRRHYLIGERIVP

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=434, Percent_Identity=29.7235023041475, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI28872784, Length=439, Percent_Identity=26.6514806378132, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI28872782, Length=439, Percent_Identity=26.6514806378132, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1786882, Length=429, Percent_Identity=30.7692307692308, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787057, Length=387, Percent_Identity=26.6149870801034, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71996771, Length=290, Percent_Identity=37.2413793103448, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17553146, Length=405, Percent_Identity=26.1728395061728, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19922432, Length=432, Percent_Identity=32.1759259259259, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI21356207, Length=397, Percent_Identity=26.448362720403, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR016027
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46142; Mature: 46142

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAETAESLKLLKNISLYTETYGCTYNAGDTEKLMEIARNQGCVPASSAEEADAILINTC
CCCCHHHHHHHHHHHHHEEEECCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
VVIDKTEQHMYERLDLYAGKLLFVTGCLPPVAADVLRTRYPKIHIIDPALIHSCYMEVGT
EEEECHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHCC
AHVGTNAVLQIARGCNGHCTYCITRLARGKLVSFSAEDIVRQAKSIVEAGATEIQLTAQD
CCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCEEEEEECC
TSSWGLDRNDGLRLPDLLRQLCAIPGNFMIRIGMANPDTLLPILDDFLDALKDPKIFLFL
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
HIPVQSGSDSVLRLMGRRYTSAQYEEICQRARKAFPEIRISTDYIAGFSGETDEDAAKSA
EEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHEECCCCCCCHHHHHHH
EQIRRTRPGKVNITRFSVRPNTPAAKMKKIPEPIKKQRSRELTDAANEVYDANNEALIGH
HHHHHCCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IMTAVVTEVVKAGSVTARDRTYQNIVIMENLEIGTEITVKITGHRRHYLIGERIVP
HHHHHHHHHHHCCCCEECCCCCCEEEEEECCCCCCEEEEEEECCCEEEECCCCCCC
>Mature Secondary Structure
MDAETAESLKLLKNISLYTETYGCTYNAGDTEKLMEIARNQGCVPASSAEEADAILINTC
CCCCHHHHHHHHHHHHHEEEECCCEECCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
VVIDKTEQHMYERLDLYAGKLLFVTGCLPPVAADVLRTRYPKIHIIDPALIHSCYMEVGT
EEEECHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHCC
AHVGTNAVLQIARGCNGHCTYCITRLARGKLVSFSAEDIVRQAKSIVEAGATEIQLTAQD
CCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCEEEEEECC
TSSWGLDRNDGLRLPDLLRQLCAIPGNFMIRIGMANPDTLLPILDDFLDALKDPKIFLFL
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEE
HIPVQSGSDSVLRLMGRRYTSAQYEEICQRARKAFPEIRISTDYIAGFSGETDEDAAKSA
EEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHEECCCCCCCHHHHHHH
EQIRRTRPGKVNITRFSVRPNTPAAKMKKIPEPIKKQRSRELTDAANEVYDANNEALIGH
HHHHHCCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IMTAVVTEVVKAGSVTARDRTYQNIVIMENLEIGTEITVKITGHRRHYLIGERIVP
HHHHHHHHHHHCCCCEECCCCCCEEEEEECCCCCCEEEEEEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]