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The map label for this gene is dsbC [H]

Identifier: 124265785

GI number: 124265785

Start: 623062

End: 623802

Strand: Direct

Name: dsbC [H]

Synonym: Mpe_A0592

Alternate gene names: 124265785

Gene position: 623062-623802 (Clockwise)

Preceding gene: 124265784

Following gene: 124265786

Centisome position: 15.41

GC content: 67.88

Gene sequence:

>741_bases
ATGAAGTTCAAGACAGCCGCGCTGGCGGCGGCAACGGTCGCAGCCATCGCCACCACCCTTGCGTTGACGGCCGTGGCCCA
GGTGCCGCAGGAGGCGGCGATCCGCAAGGCGCTCGGCGAGCGCCTGAACAGCAGCGCGAAGATCGACGAGGTCAACAAGG
CCCCGATCGCCGGCCTGTTCGAGGTGCGCATCGGCAACGACGTCTTCTACACCGACGCCGAGGGCGCCTACCTGATCCGC
GGCGAGATCCTCGACCTGAAGACCAAGCGCAACCTGACCGAGGAGCGTGTCGCCAAGCTCACCGCGATCGACTTCGCCTC
GTTGCCGCTGAAGGACGCGGTGGTCTGGAAGACCGGCACCGGCGCACGCAAGATTGCCGTCTTCGCCGACCCGAACTGCG
GCTACTGCAAGCGCTTCGAGAAGGAGCTCTCGAACGTCAAGGACCTGACGGTCTACACCTTCCTGCTGCCCATCCTGGGC
GGCGATTCGCCGGACAAGGCGAACGCGATCTGGTGCGCCAAGGACGCCTCGGTGGCGTGGCGCGCCTGGATGGTCGACGG
CGTGCAGCCGCCCAAGCTGCTGGGCGCCTGTGCGTCGCCGGTGGAGCGCAACGTCGAGCTGAGCCGCAAGCACCGGGTCA
ACGGCACGCCGGCCATCGTGTTCGAGGACGGCACCCGCGTGCCGGGCATGCTGACGGCGCCGCAACTCGAGAAGCAGCTC
GCCAGCGTCGGCAAGTCCTGA

Upstream 100 bases:

>100_bases
CCTGACTCTCGTGAATCACCTGCCGGTGCTCAAGCGCTGGCTCACCGACCGCGCGTTGCGGGGCTGACGCCCCTCCCTCC
CGCGCGCACCGAGGATCACC

Downstream 100 bases:

>100_bases
GCCGGGCGAGCGGCGTGCCGCCGCACGCGTGCGCGGCTGCGGCGACAATCCGCCCGCGCTCCGAACTTCCTCGATGGCCC
CCGTGGGATCCGCCTCTTCC

Product: putative thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKFKTAALAAATVAAIATTLALTAVAQVPQEAAIRKALGERLNSSAKIDEVNKAPIAGLFEVRIGNDVFYTDAEGAYLIR
GEILDLKTKRNLTEERVAKLTAIDFASLPLKDAVVWKTGTGARKIAVFADPNCGYCKRFEKELSNVKDLTVYTFLLPILG
GDSPDKANAIWCAKDASVAWRAWMVDGVQPPKLLGACASPVERNVELSRKHRVNGTPAIVFEDGTRVPGMLTAPQLEKQL
ASVGKS

Sequences:

>Translated_246_residues
MKFKTAALAAATVAAIATTLALTAVAQVPQEAAIRKALGERLNSSAKIDEVNKAPIAGLFEVRIGNDVFYTDAEGAYLIR
GEILDLKTKRNLTEERVAKLTAIDFASLPLKDAVVWKTGTGARKIAVFADPNCGYCKRFEKELSNVKDLTVYTFLLPILG
GDSPDKANAIWCAKDASVAWRAWMVDGVQPPKLLGACASPVERNVELSRKHRVNGTPAIVFEDGTRVPGMLTAPQLEKQL
ASVGKS
>Mature_246_residues
MKFKTAALAAATVAAIATTLALTAVAQVPQEAAIRKALGERLNSSAKIDEVNKAPIAGLFEVRIGNDVFYTDAEGAYLIR
GEILDLKTKRNLTEERVAKLTAIDFASLPLKDAVVWKTGTGARKIAVFADPNCGYCKRFEKELSNVKDLTVYTFLLPILG
GDSPDKANAIWCAKDASVAWRAWMVDGVQPPKLLGACASPVERNVELSRKHRVNGTPAIVFEDGTRVPGMLTAPQLEKQL
ASVGKS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=216, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26454; Mature: 26454

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKTAALAAATVAAIATTLALTAVAQVPQEAAIRKALGERLNSSAKIDEVNKAPIAGLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
EVRIGNDVFYTDAEGAYLIRGEILDLKTKRNLTEERVAKLTAIDFASLPLKDAVVWKTGT
EEEECCEEEEECCCCCEEEECEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
GARKIAVFADPNCGYCKRFEKELSNVKDLTVYTFLLPILGGDSPDKANAIWCAKDASVAW
CCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEE
RAWMVDGVQPPKLLGACASPVERNVELSRKHRVNGTPAIVFEDGTRVPGMLTAPQLEKQL
EEEEECCCCCHHHHHHHCCHHHCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHH
ASVGKS
HHHCCC
>Mature Secondary Structure
MKFKTAALAAATVAAIATTLALTAVAQVPQEAAIRKALGERLNSSAKIDEVNKAPIAGLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
EVRIGNDVFYTDAEGAYLIRGEILDLKTKRNLTEERVAKLTAIDFASLPLKDAVVWKTGT
EEEECCEEEEECCCCCEEEECEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
GARKIAVFADPNCGYCKRFEKELSNVKDLTVYTFLLPILGGDSPDKANAIWCAKDASVAW
CCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEE
RAWMVDGVQPPKLLGACASPVERNVELSRKHRVNGTPAIVFEDGTRVPGMLTAPQLEKQL
EEEEECCCCCHHHHHHHCCHHHCCCHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHH
ASVGKS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]