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The map label for this gene is visC [H]

Identifier: 124265784

GI number: 124265784

Start: 621910

End: 623028

Strand: Direct

Name: visC [H]

Synonym: Mpe_A0591

Alternate gene names: 124265784

Gene position: 621910-623028 (Clockwise)

Preceding gene: 124265781

Following gene: 124265785

Centisome position: 15.38

GC content: 74.89

Gene sequence:

>1119_bases
ATGAAGCATTTCGACGTGAGCGTGCGGGGCCGCGGCGCGGTGGGGAAGGCGCTGGCCTTGTCGCTCGCTCGCCTCGGGCT
GCGCGTGGCACTGTCCGGTGCCCCGGCGCCCGAGGGCCCCGATGTGCGCACCTACGCGCTCGGCGCCCGATCGGTGGCCT
TGCTGCAGCAGTTGCGGGTCTGGGAGGCGCTGCGTGCGGCCACGCCGTCGGCCGCGACCCGCGTGCTCGACATGCAGGTG
GCCGGCGACGCCGGCGGCACGCTGGCCTTCAGCGCGTGGCAGCAGTGCGTCGGCGAGCTGGCATGGATCGTCGATGCCGC
CGCGCTGGAGCGCGAACTGGCGACCGCACTGCGCTTCTCGCCGCACGTCGCGCTGCTCGACGAGGCCCCGCCGGCGGCGC
TGGTCGCGCTGTGCGAGGGCAAGGATTCGCGTGAGCGCGAGGCGCTCGGCATCGAGGTCGAACGCCACGACTATGGCCAG
CGCGCGATCGCCGCGCGGCTGGCCAGCGACCGGCCGCACCAGGGCATCGCCCGGCAATGGTTCCGCGCACCCGACGTGCT
GGCGCTGCTGCCCTTCGACCTGCCGGGCGAGGCGGGCGGCTACGGCCTGGTCTGGTCGCTGCCGGACGCGCGCGCGGCCG
AACTGCTGGCGCTGGACGACGGCGCCTTCGAGCGCGCACTGAACGAGGCCAGCCATGGCCAGGCCGGCCGGCTGGCGCTT
CGCGGCGCCCGCGCGGCCTGGCCGCTGCGACTGGCGCGTGCGACGCGCTGGCACGGGCCCGGCTGGGTGCTGCTGGGCGA
CGCCGCCCACGTGGTGCACCCGCTGGCCGGCCAGGGACTGAACCTGGGGCTGGCCGATGTCGACACGCTGTGCGCGGTGA
TCGCCGAGCGCCAGCAGCACGAGGCCTGGCGCTCGCTGGGCGACGAACGGCTGCTGGCGCGCTACGCCCGCCGCCGCGCC
GCTCCCACCTGGGCGATGGGCCGCGTGACCGACGGCCTGCTGCAACTTTTTGCCCACGAGAGTACCCCGGTGAAGGAACT
CCGCAACCGCGGCCTGACTCTCGTGAATCACCTGCCGGTGCTCAAGCGCTGGCTCACCGACCGCGCGTTGCGGGGCTGA

Upstream 100 bases:

>100_bases
GCATGGCATGGGCCAGGGCAGAAGGCCCCGTGCAGTGGCGGTCGGGGCATTGTGCCGCCGGCCCTGTTGCAACGAGGGGC
TCCCTACAATGTGAATCGCA

Downstream 100 bases:

>100_bases
CGCCCCTCCCTCCCGCGCGCACCGAGGATCACCATGAAGTTCAAGACAGCCGCGCTGGCGGCGGCAACGGTCGCAGCCAT
CGCCACCACCCTTGCGTTGA

Product: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKHFDVSVRGRGAVGKALALSLARLGLRVALSGAPAPEGPDVRTYALGARSVALLQQLRVWEALRAATPSAATRVLDMQV
AGDAGGTLAFSAWQQCVGELAWIVDAAALERELATALRFSPHVALLDEAPPAALVALCEGKDSREREALGIEVERHDYGQ
RAIAARLASDRPHQGIARQWFRAPDVLALLPFDLPGEAGGYGLVWSLPDARAAELLALDDGAFERALNEASHGQAGRLAL
RGARAAWPLRLARATRWHGPGWVLLGDAAHVVHPLAGQGLNLGLADVDTLCAVIAERQQHEAWRSLGDERLLARYARRRA
APTWAMGRVTDGLLQLFAHESTPVKELRNRGLTLVNHLPVLKRWLTDRALRG

Sequences:

>Translated_372_residues
MKHFDVSVRGRGAVGKALALSLARLGLRVALSGAPAPEGPDVRTYALGARSVALLQQLRVWEALRAATPSAATRVLDMQV
AGDAGGTLAFSAWQQCVGELAWIVDAAALERELATALRFSPHVALLDEAPPAALVALCEGKDSREREALGIEVERHDYGQ
RAIAARLASDRPHQGIARQWFRAPDVLALLPFDLPGEAGGYGLVWSLPDARAAELLALDDGAFERALNEASHGQAGRLAL
RGARAAWPLRLARATRWHGPGWVLLGDAAHVVHPLAGQGLNLGLADVDTLCAVIAERQQHEAWRSLGDERLLARYARRRA
APTWAMGRVTDGLLQLFAHESTPVKELRNRGLTLVNHLPVLKRWLTDRALRG
>Mature_372_residues
MKHFDVSVRGRGAVGKALALSLARLGLRVALSGAPAPEGPDVRTYALGARSVALLQQLRVWEALRAATPSAATRVLDMQV
AGDAGGTLAFSAWQQCVGELAWIVDAAALERELATALRFSPHVALLDEAPPAALVALCEGKDSREREALGIEVERHDYGQ
RAIAARLASDRPHQGIARQWFRAPDVLALLPFDLPGEAGGYGLVWSLPDARAAELLALDDGAFERALNEASHGQAGRLAL
RGARAAWPLRLARATRWHGPGWVLLGDAAHVVHPLAGQGLNLGLADVDTLCAVIAERQQHEAWRSLGDERLLARYARRRA
APTWAMGRVTDGLLQLFAHESTPVKELRNRGLTLVNHLPVLKRWLTDRALRG

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=259, Percent_Identity=29.3436293436293, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI32967307, Length=259, Percent_Identity=29.3436293436293, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1789273, Length=401, Percent_Identity=30.6733167082294, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789274, Length=397, Percent_Identity=31.7380352644836, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786883, Length=400, Percent_Identity=30.5, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321694, Length=125, Percent_Identity=36, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920760, Length=437, Percent_Identity=27.9176201372998, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40145; Mature: 40145

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFDVSVRGRGAVGKALALSLARLGLRVALSGAPAPEGPDVRTYALGARSVALLQQLRV
CCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCHHHHHHHHHHHH
WEALRAATPSAATRVLDMQVAGDAGGTLAFSAWQQCVGELAWIVDAAALERELATALRFS
HHHHHHCCCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHVALLDEAPPAALVALCEGKDSREREALGIEVERHDYGQRAIAARLASDRPHQGIARQW
CCEEEECCCCCHHHHHEECCCCCCCHHHHCCEEECCCCCHHHHHHHHHCCCCCCHHHHHH
FRAPDVLALLPFDLPGEAGGYGLVWSLPDARAAELLALDDGAFERALNEASHGQAGRLAL
HCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHEEEECCHHHHHHHHHHCCCCCCCEEE
RGARAAWPLRLARATRWHGPGWVLLGDAAHVVHPLAGQGLNLGLADVDTLCAVIAERQQH
CCCCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EAWRSLGDERLLARYARRRAAPTWAMGRVTDGLLQLFAHESTPVKELRNRGLTLVNHLPV
HHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEHHHHHH
LKRWLTDRALRG
HHHHHHHHHCCC
>Mature Secondary Structure
MKHFDVSVRGRGAVGKALALSLARLGLRVALSGAPAPEGPDVRTYALGARSVALLQQLRV
CCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCHHHHHHHHHHHH
WEALRAATPSAATRVLDMQVAGDAGGTLAFSAWQQCVGELAWIVDAAALERELATALRFS
HHHHHHCCCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PHVALLDEAPPAALVALCEGKDSREREALGIEVERHDYGQRAIAARLASDRPHQGIARQW
CCEEEECCCCCHHHHHEECCCCCCCHHHHCCEEECCCCCHHHHHHHHHCCCCCCHHHHHH
FRAPDVLALLPFDLPGEAGGYGLVWSLPDARAAELLALDDGAFERALNEASHGQAGRLAL
HCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHEEEECCHHHHHHHHHHCCCCCCCEEE
RGARAAWPLRLARATRWHGPGWVLLGDAAHVVHPLAGQGLNLGLADVDTLCAVIAERQQH
CCCCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EAWRSLGDERLLARYARRRAAPTWAMGRVTDGLLQLFAHESTPVKELRNRGLTLVNHLPV
HHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCEEHHHHHH
LKRWLTDRALRG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]