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The map label for this gene is fliI [H]

Identifier: 124265761

GI number: 124265761

Start: 600024

End: 601487

Strand: Direct

Name: fliI [H]

Synonym: Mpe_A0568

Alternate gene names: 124265761

Gene position: 600024-601487 (Clockwise)

Preceding gene: 124265760

Following gene: 124265762

Centisome position: 14.84

GC content: 72.47

Gene sequence:

>1464_bases
ATGAACGCCCCGACCGAAGGCTGGCTGCCCGCCGCCACGCCGGCGACCGAGCGCCCTGCAGCGCCGCCCGCCGCGCTGCC
GGCGTCGTGGCAACGCTACATGGATGATCTGAAGGCGCATGCCCTCGGCCCGGTGCCGCTGGAGGCGCAGGGCACGCTGG
TGCGCGTGGCCGGACTGGTGCTGGAGGCCGCCGGCATCCGCGTGCCGGTCGGCTCGGTCTGCGAGGTGCGCATGGACGGC
CAGCCGCCCGTGCTGGCTGAGGTGGTCGGCTTCGCCGCCGACCGTGCCTACCTGATGCCCACCGGCGAGCTGCACGGCCT
GGCCAGCGGCGCGCGGGTGGTCCCGCGCTCGACCCCGAGCGTGGCGCCGGTGCTCGGCGAGGCGCATCACCCGTGGCGTC
GCAGCGAAGACCGCACCCGCCACCTGCCGATCGGCGACGGCCTGCTGGGCCGCGTGATCGACCCGCTGGGCATGCCGCTC
GACCGGCTCGGCCCGATCGGCGCCGTGCGCAACGAGCCGCTGGTGCGTCGCCCCATCAACGCGATGGAGCGCGACCCGGT
GCGCGAGCCGCTGGACACGGGCGTGCGCGCGATCAACGCCATGCTCACCGTCGGCCGCGGCCAGCGCATCGGGCTGTTCG
CCGGCTCCGGCGTCGGCAAGTCGGTGCTGCTGGGCATGATGGCCAAGTACACCGCGGCCGACGTCATCGTCGTCGGCCTG
ATCGGCGAGCGCGGACGCGAGGTCAAGGAATTCATCGAGGACATCCTCGGCGAGGAGGGCCTGAAGCGCTCCATCGTCGT
GGCGGCGCCGGCCGACTCGCCGCCGCTGACGCGCATGCAGGGGGCCGCCTACGCCACCGCGATCGCCGAGCACTTCCGCG
ACCGCGGCCAGCACGTGCTGCTGCTGATGGACAGCCTGACCCGTTACGCGATGGCGCAACGCGAGATCGCGCTGGCCATC
GGCGAACCGCCGGCCACCAAGGGCTATCCGCCGAGCTGCTTCGCGAAGCTGCCGCAACTGGTCGAGCGCAGCGGCAACGG
CCTCAACGGCTGCGGTTCGATCACCGCGTTCTACACGGTGCTCAGCGAAGGCGACGACCAGCAGGACCCGATCGCCGACG
CGGCCCGCGCCATCCTCGACGGCCACATCGTGCTGTCGCGCGACCTGGCCGAGAGTGGCCATTACCCGGCGATCGACATC
GAACGCTCGGCCTCGCGCGTGATGCACAACGTGGCACGGCCCGAACACCTGCAGGCGGCGCGCCGCCTGCGCCAGCTGTG
GTCGCGCTATCAGAAGGCGCGCGACCTGATCGCGCTGGGCGCCTATGCGCCCGGCCACGATGTCGAACTCGACCTCGCGG
TCAAGCAGCACGATGCGATGCGCACGCTGCTGCAGCAGGACATGCACGACGCCTCGCGGCTGACCGACAGCGTGCGCCAG
TTGCGCCAGCTGACCGGCATCTGA

Upstream 100 bases:

>100_bases
GCCGTGCCATGGACGGCATGGGACAGCGCGCTGCCTACGAGGTGGCGCCGTCGGCCGACGACGCGGCCGCACCGGTGACC
GACGAGAACGGGGCGGGCGC

Downstream 100 bases:

>100_bases
CCCGCGAGCCCCACCGACCGAACGTTCGCCCCCGGAAAGACTCCATGAGCGCCCTCCAGCCCCTGAACACCCTGCTCGAA
CAGACCACGGTCGCGCGCGA

Product: flagellar biosynthesis ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MNAPTEGWLPAATPATERPAAPPAALPASWQRYMDDLKAHALGPVPLEAQGTLVRVAGLVLEAAGIRVPVGSVCEVRMDG
QPPVLAEVVGFAADRAYLMPTGELHGLASGARVVPRSTPSVAPVLGEAHHPWRRSEDRTRHLPIGDGLLGRVIDPLGMPL
DRLGPIGAVRNEPLVRRPINAMERDPVREPLDTGVRAINAMLTVGRGQRIGLFAGSGVGKSVLLGMMAKYTAADVIVVGL
IGERGREVKEFIEDILGEEGLKRSIVVAAPADSPPLTRMQGAAYATAIAEHFRDRGQHVLLLMDSLTRYAMAQREIALAI
GEPPATKGYPPSCFAKLPQLVERSGNGLNGCGSITAFYTVLSEGDDQQDPIADAARAILDGHIVLSRDLAESGHYPAIDI
ERSASRVMHNVARPEHLQAARRLRQLWSRYQKARDLIALGAYAPGHDVELDLAVKQHDAMRTLLQQDMHDASRLTDSVRQ
LRQLTGI

Sequences:

>Translated_487_residues
MNAPTEGWLPAATPATERPAAPPAALPASWQRYMDDLKAHALGPVPLEAQGTLVRVAGLVLEAAGIRVPVGSVCEVRMDG
QPPVLAEVVGFAADRAYLMPTGELHGLASGARVVPRSTPSVAPVLGEAHHPWRRSEDRTRHLPIGDGLLGRVIDPLGMPL
DRLGPIGAVRNEPLVRRPINAMERDPVREPLDTGVRAINAMLTVGRGQRIGLFAGSGVGKSVLLGMMAKYTAADVIVVGL
IGERGREVKEFIEDILGEEGLKRSIVVAAPADSPPLTRMQGAAYATAIAEHFRDRGQHVLLLMDSLTRYAMAQREIALAI
GEPPATKGYPPSCFAKLPQLVERSGNGLNGCGSITAFYTVLSEGDDQQDPIADAARAILDGHIVLSRDLAESGHYPAIDI
ERSASRVMHNVARPEHLQAARRLRQLWSRYQKARDLIALGAYAPGHDVELDLAVKQHDAMRTLLQQDMHDASRLTDSVRQ
LRQLTGI
>Mature_487_residues
MNAPTEGWLPAATPATERPAAPPAALPASWQRYMDDLKAHALGPVPLEAQGTLVRVAGLVLEAAGIRVPVGSVCEVRMDG
QPPVLAEVVGFAADRAYLMPTGELHGLASGARVVPRSTPSVAPVLGEAHHPWRRSEDRTRHLPIGDGLLGRVIDPLGMPL
DRLGPIGAVRNEPLVRRPINAMERDPVREPLDTGVRAINAMLTVGRGQRIGLFAGSGVGKSVLLGMMAKYTAADVIVVGL
IGERGREVKEFIEDILGEEGLKRSIVVAAPADSPPLTRMQGAAYATAIAEHFRDRGQHVLLLMDSLTRYAMAQREIALAI
GEPPATKGYPPSCFAKLPQLVERSGNGLNGCGSITAFYTVLSEGDDQQDPIADAARAILDGHIVLSRDLAESGHYPAIDI
ERSASRVMHNVARPEHLQAARRLRQLWSRYQKARDLIALGAYAPGHDVELDLAVKQHDAMRTLLQQDMHDASRLTDSVRQ
LRQLTGI

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=311, Percent_Identity=32.475884244373, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI50345984, Length=341, Percent_Identity=29.6187683284457, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI4757810, Length=341, Percent_Identity=29.6187683284457, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI19913424, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI19913428, Length=320, Percent_Identity=26.5625, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913426, Length=320, Percent_Identity=26.5625, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788251, Length=437, Percent_Identity=59.7254004576659, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1790170, Length=303, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790172, Length=354, Percent_Identity=26.5536723163842, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1790217, Length=241, Percent_Identity=28.6307053941909, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144756, Length=312, Percent_Identity=32.0512820512821, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71988080, Length=342, Percent_Identity=29.8245614035088, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71988063, Length=342, Percent_Identity=29.8245614035088, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71988074, Length=328, Percent_Identity=28.0487804878049, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17565854, Length=318, Percent_Identity=28.6163522012579, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=317, Percent_Identity=27.4447949526814, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=317, Percent_Identity=26.1829652996845, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322581, Length=309, Percent_Identity=33.0097087378641, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6319370, Length=342, Percent_Identity=30.1169590643275, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319603, Length=320, Percent_Identity=28.125, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320016, Length=263, Percent_Identity=27.3764258555133, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24638766, Length=310, Percent_Identity=32.258064516129, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574560, Length=308, Percent_Identity=31.4935064935065, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24658560, Length=356, Percent_Identity=28.6516853932584, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI20129479, Length=320, Percent_Identity=29.0625, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583992, Length=320, Percent_Identity=27.8125, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583988, Length=322, Percent_Identity=27.3291925465839, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24583986, Length=322, Percent_Identity=27.3291925465839, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24583984, Length=322, Percent_Identity=27.3291925465839, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281361666, Length=324, Percent_Identity=27.4691358024691, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646341, Length=324, Percent_Identity=27.4691358024691, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136796, Length=324, Percent_Identity=27.4691358024691, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 52429; Mature: 52429

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPTEGWLPAATPATERPAAPPAALPASWQRYMDDLKAHALGPVPLEAQGTLVRVAGLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LEAAGIRVPVGSVCEVRMDGQPPVLAEVVGFAADRAYLMPTGELHGLASGARVVPRSTPS
HHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHCCCCCEECCCCCCC
VAPVLGEAHHPWRRSEDRTRHLPIGDGLLGRVIDPLGMPLDRLGPIGAVRNEPLVRRPIN
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCHHHCCHH
AMERDPVREPLDTGVRAINAMLTVGRGQRIGLFAGSGVGKSVLLGMMAKYTAADVIVVGL
HHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEEEE
IGERGREVKEFIEDILGEEGLKRSIVVAAPADSPPLTRMQGAAYATAIAEHFRDRGQHVL
CCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHCCCEEE
LLMDSLTRYAMAQREIALAIGEPPATKGYPPSCFAKLPQLVERSGNGLNGCGSITAFYTV
EHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSEGDDQQDPIADAARAILDGHIVLSRDLAESGHYPAIDIERSASRVMHNVARPEHLQAA
HHCCCCCCCHHHHHHHHHHCCCEEEEHHHHHCCCCCCEECHHHHHHHHHHHCCCHHHHHH
RRLRQLWSRYQKARDLIALGAYAPGHDVELDLAVKQHDAMRTLLQQDMHDASRLTDSVRQ
HHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQLTGI
HHHHHCC
>Mature Secondary Structure
MNAPTEGWLPAATPATERPAAPPAALPASWQRYMDDLKAHALGPVPLEAQGTLVRVAGLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LEAAGIRVPVGSVCEVRMDGQPPVLAEVVGFAADRAYLMPTGELHGLASGARVVPRSTPS
HHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHCCCCCEECCCCCCC
VAPVLGEAHHPWRRSEDRTRHLPIGDGLLGRVIDPLGMPLDRLGPIGAVRNEPLVRRPIN
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCHHHCCHH
AMERDPVREPLDTGVRAINAMLTVGRGQRIGLFAGSGVGKSVLLGMMAKYTAADVIVVGL
HHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEEEE
IGERGREVKEFIEDILGEEGLKRSIVVAAPADSPPLTRMQGAAYATAIAEHFRDRGQHVL
CCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHCCCEEE
LLMDSLTRYAMAQREIALAIGEPPATKGYPPSCFAKLPQLVERSGNGLNGCGSITAFYTV
EHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSEGDDQQDPIADAARAILDGHIVLSRDLAESGHYPAIDIERSASRVMHNVARPEHLQAA
HHCCCCCCCHHHHHHHHHHCCCEEEEHHHHHCCCCCCEECHHHHHHHHHHHCCCHHHHHH
RRLRQLWSRYQKARDLIALGAYAPGHDVELDLAVKQHDAMRTLLQQDMHDASRLTDSVRQ
HHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQLTGI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]