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The map label for this gene is ftsA [H]

Identifier: 124265659

GI number: 124265659

Start: 506716

End: 507945

Strand: Direct

Name: ftsA [H]

Synonym: Mpe_A0466

Alternate gene names: 124265659

Gene position: 506716-507945 (Clockwise)

Preceding gene: 124265658

Following gene: 124265660

Centisome position: 12.53

GC content: 68.05

Gene sequence:

>1230_bases
ATGGCCAAGGAATACAAGGATCTCGTCGTCGGGCTCGACATCGGCACCGCCAAGGTGATGGCGGTGGTGGCCGAGGTGCT
GCCCGAGGGTGAGCTGCGCGTCGCCGGCATCGGCACCGCGCCGGCCCATGGGCTCAAGCGCGGCGTGGTGGTGAACATCG
ACGCGACGGTCCAGTCCATCCAGCAGGCCTTGAAGGAGGCCGAGATGATGGCCGACTGCAAGATCACGCGCGTCTACACC
GGCATCACCGGCAGCCACATCCGCGGCCAGAACTCCACCGGCATGGTGATCGTGCGCGACAAGGAGGTCACGCCGGTCGA
CGTGGCGCGCGTGATCGAGACCGCCAAGGCGATCAACATCCCGAACGACCAGCGCATGCTGCTGGTCGAGGCGCAGGAGT
TCGTGATCGACGGCCACGAGGTCAAGGAGCCGATCGGCATGAGCGGCGGCCGCCTCGAGGTCAAGGTGCACATCGTGACC
GGCGCGCAGAGCGCGGCCGAGAACATCATCAAGTGCGTGCGCCGCTGCGGGCTGGAAGTGGACATGCTGGTACTCAACCC
CAGCGCGTCCAGCCACGCGGTGCTGACCGACGACGAGAAGGACCTGGGCGTCGCGCTGGTCGACATCGGCGCCGGCACGA
CCGACGTGTCGATCTTCACCGACGGCTCGGTGCGCCACACCGCGGTGATCCCGATCGCCGGCGACCTGATCACCAGCGAC
ATCGCGATGGCGCTGCGCACGCCGACCAAGGACGCCGAGGAGATCAAGGTCGAGCACGGCGTGGCCAAGCAGCTGCTGGC
CGATCCGAACGAGCAGGTCGAGGTGCCGGGGCTCGGCGACCGCGGCCCGCGCATGCTCAGCCGCCAGGCGCTGGCCGGCG
TGATCGAGCCGCGCGTCGAGGAAATCTTCTCGCTGGTGCACCAGGTGATCCGCGAGAGCGGCTACGAGGAGCTGCTGTCC
AGCGGCATCGTGCTCACCGGCGGCACCGCGGTGATGCCCGGCATGGTCGAGCTGGGCGAGGACATCTTTCTGAAGCCGGT
GAGGAAGGGGCTGCCCACCTACGCCGGCGCACTGTCAGACATGGTGGCGAGCCCGCGCTCGGCCACCGTGATGGGCTTGC
TCGAAGAGGCGAGGCTCGCGCGCACGCGCGGCATGAAGGCAGCGCAGCAGGCGGGGTCGGTCCAGACCCTGTTCGGCCGC
GTCAAGGATTGGTTCATCGGGAATTTTTAG

Upstream 100 bases:

>100_bases
TGCGCCACGCCGACGGCTACGCGCTGCGGCTCAAGGGCATCGGCACGGCGGCGCCGACGGCGGCGGCAGGCAGGAAATAG
AAGGAAAAGGCGGGAAGCAC

Downstream 100 bases:

>100_bases
GGCGTCATCCAGCCCACGTTTTCAACCGGCAACTGCATCAGACGAAGGAGGTCCACCATGGCCATCGAGATGATTGAAGA
ATTCGAGCTCGGCACGAAGA

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAKEYKDLVVGLDIGTAKVMAVVAEVLPEGELRVAGIGTAPAHGLKRGVVVNIDATVQSIQQALKEAEMMADCKITRVYT
GITGSHIRGQNSTGMVIVRDKEVTPVDVARVIETAKAINIPNDQRMLLVEAQEFVIDGHEVKEPIGMSGGRLEVKVHIVT
GAQSAAENIIKCVRRCGLEVDMLVLNPSASSHAVLTDDEKDLGVALVDIGAGTTDVSIFTDGSVRHTAVIPIAGDLITSD
IAMALRTPTKDAEEIKVEHGVAKQLLADPNEQVEVPGLGDRGPRMLSRQALAGVIEPRVEEIFSLVHQVIRESGYEELLS
SGIVLTGGTAVMPGMVELGEDIFLKPVRKGLPTYAGALSDMVASPRSATVMGLLEEARLARTRGMKAAQQAGSVQTLFGR
VKDWFIGNF

Sequences:

>Translated_409_residues
MAKEYKDLVVGLDIGTAKVMAVVAEVLPEGELRVAGIGTAPAHGLKRGVVVNIDATVQSIQQALKEAEMMADCKITRVYT
GITGSHIRGQNSTGMVIVRDKEVTPVDVARVIETAKAINIPNDQRMLLVEAQEFVIDGHEVKEPIGMSGGRLEVKVHIVT
GAQSAAENIIKCVRRCGLEVDMLVLNPSASSHAVLTDDEKDLGVALVDIGAGTTDVSIFTDGSVRHTAVIPIAGDLITSD
IAMALRTPTKDAEEIKVEHGVAKQLLADPNEQVEVPGLGDRGPRMLSRQALAGVIEPRVEEIFSLVHQVIRESGYEELLS
SGIVLTGGTAVMPGMVELGEDIFLKPVRKGLPTYAGALSDMVASPRSATVMGLLEEARLARTRGMKAAQQAGSVQTLFGR
VKDWFIGNF
>Mature_408_residues
AKEYKDLVVGLDIGTAKVMAVVAEVLPEGELRVAGIGTAPAHGLKRGVVVNIDATVQSIQQALKEAEMMADCKITRVYTG
ITGSHIRGQNSTGMVIVRDKEVTPVDVARVIETAKAINIPNDQRMLLVEAQEFVIDGHEVKEPIGMSGGRLEVKVHIVTG
AQSAAENIIKCVRRCGLEVDMLVLNPSASSHAVLTDDEKDLGVALVDIGAGTTDVSIFTDGSVRHTAVIPIAGDLITSDI
AMALRTPTKDAEEIKVEHGVAKQLLADPNEQVEVPGLGDRGPRMLSRQALAGVIEPRVEEIFSLVHQVIRESGYEELLSS
GIVLTGGTAVMPGMVELGEDIFLKPVRKGLPTYAGALSDMVASPRSATVMGLLEEARLARTRGMKAAQQAGSVQTLFGRV
KDWFIGNF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=414, Percent_Identity=43.719806763285, Blast_Score=352, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 43551; Mature: 43420

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEYKDLVVGLDIGTAKVMAVVAEVLPEGELRVAGIGTAPAHGLKRGVVVNIDATVQSI
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCEEEEEHHHHHHH
QQALKEAEMMADCKITRVYTGITGSHIRGQNSTGMVIVRDKEVTPVDVARVIETAKAINI
HHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PNDQRMLLVEAQEFVIDGHEVKEPIGMSGGRLEVKVHIVTGAQSAAENIIKCVRRCGLEV
CCCCEEEEEEHHHHHCCCHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCEE
DMLVLNPSASSHAVLTDDEKDLGVALVDIGAGTTDVSIFTDGSVRHTAVIPIAGDLITSD
EEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCEEEEEEEEECCHHHHHH
IAMALRTPTKDAEEIKVEHGVAKQLLADPNEQVEVPGLGDRGPRMLSRQALAGVIEPRVE
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHCHHHH
EIFSLVHQVIRESGYEELLSSGIVLTGGTAVMPGMVELGEDIFLKPVRKGLPTYAGALSD
HHHHHHHHHHHHCCHHHHHHCCEEEECCCCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHH
MVASPRSATVMGLLEEARLARTRGMKAAQQAGSVQTLFGRVKDWFIGNF
HHCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKEYKDLVVGLDIGTAKVMAVVAEVLPEGELRVAGIGTAPAHGLKRGVVVNIDATVQSI
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCCEEEEEHHHHHHH
QQALKEAEMMADCKITRVYTGITGSHIRGQNSTGMVIVRDKEVTPVDVARVIETAKAINI
HHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PNDQRMLLVEAQEFVIDGHEVKEPIGMSGGRLEVKVHIVTGAQSAAENIIKCVRRCGLEV
CCCCEEEEEEHHHHHCCCHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCEE
DMLVLNPSASSHAVLTDDEKDLGVALVDIGAGTTDVSIFTDGSVRHTAVIPIAGDLITSD
EEEEECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCEEEEEEEEECCHHHHHH
IAMALRTPTKDAEEIKVEHGVAKQLLADPNEQVEVPGLGDRGPRMLSRQALAGVIEPRVE
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHCHHHH
EIFSLVHQVIRESGYEELLSSGIVLTGGTAVMPGMVELGEDIFLKPVRKGLPTYAGALSD
HHHHHHHHHHHHCCHHHHHHCCEEEECCCCCCCCHHHHCCHHHHHHHHHCCCHHHHHHHH
MVASPRSATVMGLLEEARLARTRGMKAAQQAGSVQTLFGRVKDWFIGNF
HHCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]