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The map label for this gene is murG

Identifier: 124265655

GI number: 124265655

Start: 502306

End: 503409

Strand: Direct

Name: murG

Synonym: Mpe_A0462

Alternate gene names: 124265655

Gene position: 502306-503409 (Clockwise)

Preceding gene: 124265654

Following gene: 124265656

Centisome position: 12.42

GC content: 72.55

Gene sequence:

>1104_bases
ATGACTCAACGCCACCTCGTCGTCATGGCCGCCGGCACCGGCGGCCACATCATTCCCGGTCTGGCCGTCGCCCAGGAGAT
GCAGCACCGCGGCTGGACCGTCAGCTGGCTCGGCACCGAGCAGGGCATGGAGAACCGCCTCGTGCCGCCGGCCGCCGAGT
CGGGCATCGAGATGGACACCATCGCCTTCAGCGGGCTGCGCGGCAAGGGCCTGCTGCACACGCTGACCGGCGGCCTGCGG
CTGCTGGGCGCGTTCGCGGCCTGCGCGAAGATCCTGCGCCGCCGCGCCACCACCGCGGTGCTGGGCATGGGTGGTTACGT
GTGCTTCCCGGGCGGGCTGATGGCCTCGCTGCTGGGCAAGCCGCTGATCCTGGTCAATGCCGATGCGGCGCTGCTGATGA
GCAACCGCGCGCTGAAGCCGGTGGCCGACCGCATCGCCTTCGGCTTCGACGGCGCCGCGGCAGCCACCACGAGGCAGGCG
GTCGTCACCGGCAATCCGGTGCGTGCCGAGATCGAGACACTGCCCGAGCCGCCGGTGCGCTACGCCGGGCGCGAGGGACC
GCTGCGCGTGCTGGTGGTCGGGGGCAGCCTGGGGGCGCGCGTGCTCAACGAGACCCTGCCGCAGGCGTTGGCCCTGCTGG
CGCCCGCGGAACGGCCGCGCGTGCTGCACCAGACCGGCCAGCTCAACCGCGACGGCGTGAAGGAGGCCTATGCCGCCGTG
GGCATCGACGACGGTGTCGAGGTGCTGGCCTTCATCGACGACATGGCCGCGCGGCTCGCGCACTGCGACGTGGTGATCTG
CCGTGCCGGCGCAGTGACGGTCAGCGAGCTGTGTGCCGCCGGCGTGGCGAGTGTCCTGGTGCCGCTGATCGTGAGCACCA
CCTCGCACCAGCGCGACAACGCGCTCTACATGGCGCAGCACGGTGCGGCGATCCACCTGCCGCAGAGCGAGCTGACGCCG
CAGGCGCTGGCCGAGCGGCTGCGCACGCTGGACCGGCCGCAGTTGCTGGGCATGGCCGAGAAGGCGCGTGCGCTGTCACG
CCCGCGCGCCGCGGCCCGTGTGGCCGACGAGATCGAGCGTCTCGTGCGAAAGGACGGGCTGTGA

Upstream 100 bases:

>100_bases
AGGGCATGGCTGAGGCTATCGGCTTGGTGCAGTGCCGTGCGCGGCAGCCCGCCGGGTCTCGCCCCGGCGCGGTGCCGTCC
GCAGGCGCGGGAGTCACGCC

Downstream 100 bases:

>100_bases
TGAACCTGCAGACACTTGCGCACGCGGGCCGAGCGCCGGGCCGCCCCAAGCCGGCCCGTATCCCCGCGGGGGATCGGCCG
ACGTACGCGTCGGACGAGGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTQRHLVVMAAGTGGHIIPGLAVAQEMQHRGWTVSWLGTEQGMENRLVPPAAESGIEMDTIAFSGLRGKGLLHTLTGGLR
LLGAFAACAKILRRRATTAVLGMGGYVCFPGGLMASLLGKPLILVNADAALLMSNRALKPVADRIAFGFDGAAAATTRQA
VVTGNPVRAEIETLPEPPVRYAGREGPLRVLVVGGSLGARVLNETLPQALALLAPAERPRVLHQTGQLNRDGVKEAYAAV
GIDDGVEVLAFIDDMAARLAHCDVVICRAGAVTVSELCAAGVASVLVPLIVSTTSHQRDNALYMAQHGAAIHLPQSELTP
QALAERLRTLDRPQLLGMAEKARALSRPRAAARVADEIERLVRKDGL

Sequences:

>Translated_367_residues
MTQRHLVVMAAGTGGHIIPGLAVAQEMQHRGWTVSWLGTEQGMENRLVPPAAESGIEMDTIAFSGLRGKGLLHTLTGGLR
LLGAFAACAKILRRRATTAVLGMGGYVCFPGGLMASLLGKPLILVNADAALLMSNRALKPVADRIAFGFDGAAAATTRQA
VVTGNPVRAEIETLPEPPVRYAGREGPLRVLVVGGSLGARVLNETLPQALALLAPAERPRVLHQTGQLNRDGVKEAYAAV
GIDDGVEVLAFIDDMAARLAHCDVVICRAGAVTVSELCAAGVASVLVPLIVSTTSHQRDNALYMAQHGAAIHLPQSELTP
QALAERLRTLDRPQLLGMAEKARALSRPRAAARVADEIERLVRKDGL
>Mature_366_residues
TQRHLVVMAAGTGGHIIPGLAVAQEMQHRGWTVSWLGTEQGMENRLVPPAAESGIEMDTIAFSGLRGKGLLHTLTGGLRL
LGAFAACAKILRRRATTAVLGMGGYVCFPGGLMASLLGKPLILVNADAALLMSNRALKPVADRIAFGFDGAAAATTRQAV
VTGNPVRAEIETLPEPPVRYAGREGPLRVLVVGGSLGARVLNETLPQALALLAPAERPRVLHQTGQLNRDGVKEAYAAVG
IDDGVEVLAFIDDMAARLAHCDVVICRAGAVTVSELCAAGVASVLVPLIVSTTSHQRDNALYMAQHGAAIHLPQSELTPQ
ALAERLRTLDRPQLLGMAEKARALSRPRAAARVADEIERLVRKDGL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=360, Percent_Identity=45.5555555555556, Blast_Score=278, Evalue=6e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_METPP (A2SCY5)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019659.1
- ProteinModelPortal:   A2SCY5
- SMR:   A2SCY5
- STRING:   A2SCY5
- GeneID:   4784181
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0462
- NMPDR:   fig|279263.3.peg.2706
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   A2SCY5
- ProtClustDB:   PRK00726
- BioCyc:   MPET420662:MPE_A0462-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38651; Mature: 38519

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRHLVVMAAGTGGHIIPGLAVAQEMQHRGWTVSWLGTEQGMENRLVPPAAESGIEMDT
CCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHCCCCCHH
IAFSGLRGKGLLHTLTGGLRLLGAFAACAKILRRRATTAVLGMGGYVCFPGGLMASLLGK
HEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCC
PLILVNADAALLMSNRALKPVADRIAFGFDGAAAATTRQAVVTGNPVRAEIETLPEPPVR
CEEEEECCHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCCEEEECCCCEEHHHCCCCCCHH
YAGREGPLRVLVVGGSLGARVLNETLPQALALLAPAERPRVLHQTGQLNRDGVKEAYAAV
HCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHC
GIDDGVEVLAFIDDMAARLAHCDVVICRAGAVTVSELCAAGVASVLVPLIVSTTSHQRDN
CCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
ALYMAQHGAAIHLPQSELTPQALAERLRTLDRPQLLGMAEKARALSRPRAAARVADEIER
EEEEEECCCEEECCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LVRKDGL
HHHHCCC
>Mature Secondary Structure 
TQRHLVVMAAGTGGHIIPGLAVAQEMQHRGWTVSWLGTEQGMENRLVPPAAESGIEMDT
CCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHCCCCCHH
IAFSGLRGKGLLHTLTGGLRLLGAFAACAKILRRRATTAVLGMGGYVCFPGGLMASLLGK
HEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCC
PLILVNADAALLMSNRALKPVADRIAFGFDGAAAATTRQAVVTGNPVRAEIETLPEPPVR
CEEEEECCHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCCEEEECCCCEEHHHCCCCCCHH
YAGREGPLRVLVVGGSLGARVLNETLPQALALLAPAERPRVLHQTGQLNRDGVKEAYAAV
HCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHC
GIDDGVEVLAFIDDMAARLAHCDVVICRAGAVTVSELCAAGVASVLVPLIVSTTSHQRDN
CCCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
ALYMAQHGAAIHLPQSELTPQALAERLRTLDRPQLLGMAEKARALSRPRAAARVADEIER
EEEEEECCCEEECCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LVRKDGL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA