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The map label for this gene is groES [H]

Identifier: 124265620

GI number: 124265620

Start: 463403

End: 463693

Strand: Direct

Name: groES [H]

Synonym: Mpe_A0427

Alternate gene names: 124265620

Gene position: 463403-463693 (Clockwise)

Preceding gene: 124265619

Following gene: 124265621

Centisome position: 11.46

GC content: 60.48

Gene sequence:

>291_bases
ATGAAACTTCGTCCTTTGCACGATCGCGTGATCGTCAAGCGCCTCGAACAGGAAACCAAGACCGCTTCGGGCATCGTGAT
CCCCGACAACGCCGCCGAGAAGCCCGACCAGGGTGAAGTGCTGGCCGTGGGTCCGGGCAAGCGCAACGACAAGGGCGACT
TCATCGCCCTGAACTGCAAGGTCGGCGATCGCGTGCTGTTCGGCAAGTACAGCGGCCAGACCGTCAAGGTCGACGGTGAC
GAACTGCTGGTGATGCGCGAGGAAGACCTCTTCGCCGTGGTTGAAAAGTAA

Upstream 100 bases:

>100_bases
AGCCGGAGACGGCATCATCGTCTCTGGCTGCGCAATTGTGAGCTTGCGCTAACTGCGCGAAACAAGTCCGTAGATATTCG
ATACCCATCAAGGAGATGCG

Downstream 100 bases:

>100_bases
ATCGCGTGCGATTTGCTTTCGTCGCAGGCTGACTTCGCGCAGCGAAGTCAAGGCCCCAAGGGTCGGCCGTAGACAGAAGA
ATTCCCCGGCGCGAGCCGGC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKLRPLHDRVIVKRLEQETKTASGIVIPDNAAEKPDQGEVLAVGPGKRNDKGDFIALNCKVGDRVLFGKYSGQTVKVDGD
ELLVMREEDLFAVVEK

Sequences:

>Translated_96_residues
MKLRPLHDRVIVKRLEQETKTASGIVIPDNAAEKPDQGEVLAVGPGKRNDKGDFIALNCKVGDRVLFGKYSGQTVKVDGD
ELLVMREEDLFAVVEK
>Mature_96_residues
MKLRPLHDRVIVKRLEQETKTASGIVIPDNAAEKPDQGEVLAVGPGKRNDKGDFIALNCKVGDRVLFGKYSGQTVKVDGD
ELLVMREEDLFAVVEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=52.0833333333333, Blast_Score=95, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=43.956043956044, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=93, Percent_Identity=40.8602150537634, Blast_Score=79, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=45.360824742268, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=42.7083333333333, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10606; Mature: 10606

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPLHDRVIVKRLEQETKTASGIVIPDNAAEKPDQGEVLAVGPGKRNDKGDFIALNCK
CCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDRVLFGKYSGQTVKVDGDELLVMREEDLFAVVEK
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MKLRPLHDRVIVKRLEQETKTASGIVIPDNAAEKPDQGEVLAVGPGKRNDKGDFIALNCK
CCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDRVLFGKYSGQTVKVDGDELLVMREEDLFAVVEK
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA