Click here to switch to the map view.

The map label for this gene is acoR [H]

Identifier: 124265558

GI number: 124265558

Start: 401863

End: 403893

Strand: Direct

Name: acoR [H]

Synonym: Mpe_A0365

Alternate gene names: 124265558

Gene position: 401863-403893 (Clockwise)

Preceding gene: 124265549

Following gene: 124265559

Centisome position: 9.94

GC content: 71.44

Gene sequence:

>2031_bases
TTGATCCTGTCCCACCAACACGTCGACGAGATCCGCCGCATCGCCGCGGGTCACGCCCCCGCGGCCGGCACGCCCGACAG
CCTGATCCACCGCTCCTGGCACCGCTGCGTCAACACGCACGGCCTCGATCCCGCGCAGTCCTTCGGCCCGCGCGTCGAGA
GCCCGACACGGCTGCGCGAATCGCGCGAGCGCATCGAGGAGTACCTGCAGGTCGCGCGCGGCGGCATGGAGCAGCTCTTC
AAGCGCGTGTCCGACCTCGGCTACGTGCTGCTGCTGACCGACGCCGACGGCGTGACGGTCGACTACATCGGCAACGACTC
CTGGGGCAAGGACGCGCAGCGCGCCGGCCTCTACCTCGGCGCCAACTGGAAGGAAGAGATCGCCGGCACCAACGGCATCG
GCACCTGCATCTACGAACAGGCCGCGCTCACCTGCCACCGCGACGACCACTTCTACACCGGCAACGTCGGCCTGAGCTGC
AACACCGCGCCGCTGTTCCATCCCGACGGCAAGCTGATGGGCGTGCTCGACGTGTCGGCGCTGGCCATGCCCAACGCGCG
CGAGAGCCAGCACCTCGCGCTGCACCTCACCACGCTGTACGGGCAGATGATCGAGGACGCCAACTTCGTGCGTCACTTCC
GCGATCACTGGATCCTGCGGCTGGCCACCAGCTGGGCGCTGGTCGACGTGCTGGGCGACATGATGCTGGCCTTCGACAGC
GACGGCGTGCTGGCCGGCGCCAGCACCGGCGCCCGCAAGTGGCTGTCCGGCCTGGCGCTGCAGGGCGGCGACGACGCCCC
CATCGAGGGCCGCCACCTGACCGACGTGTTCCGCTGCTCGATGGACGACATCTGGCGCCTCGCGCGCTCGTCCAACGTGA
TGGACCGCGCGCTGCTGTCGGCGTTCGACCACCAGAGCTACTTCGGCAGCGTGGTCGCGCCGCGCATGCGCAGCGCGGCC
AGCAGCGCCGCGGGCCCGCGCGACGTGACCGACGCGGCGCCCGCGCTCGCGCCGGCCAGCCCGGCGCTCGAACGCCTGGC
CGGCGACGACAAGCAGATGCGCGCGCTGCAGGACCAGGCGCGCCGCCTGGCCAACAAGCGCATCAACATCCTGATCCAGG
GCGAGACCGGCACCGGCAAGGAAGTGTTCGCGAAGGCGCTGCACGAGTCGAGCACGCGCCACGACAAGCCCTTCGTCGCC
GTCAACTGTGCGTCGATCCCCGAGTCGCTGATCGAGAGCGAGCTGTTCGGCTACACCGCCGGCACCTTCACCGGCGCGCG
CAGCCGCGGCATGAAGGGCCTGATCGTGCAGGCCCACGGCGGCACGCTGTTCCTCGACGAGATCGGCGACATGCCGCTGC
ATCTGCAGACGCGCCTGCTGCGCGTGCTGTCCGAGCACGAGGTGCTGCCGCTCGGCGCCGACCGGCCCATCCGCGTGGAG
CTCACCGTCATCGCCGCCTCGCACCGCGACCTGCGCCAGCTCATCGCCGCCGGCAGCTTCCGCGAGGACCTGTACTACCG
CCTGTGCGGCGCCACACTGCCGCTGCCGGCGCTGCGCGACCGCCGCGATCTCGGCTACCTGATCGAGCTGATCCTGCGCG
AGGAAGCCGAGCACCTGGACACCCGCGCCTACATCGCCGACGAGGCGCTGGAGCTGCTGGAGCGCTACGAATGGCCGGGC
AACGTGCGGCAGCTGCGCAACGTGCTGCGCTTCGGCCTCGCGCTGTCGGACGGCGAGGGCATCTATCCCGAGCACCTGCC
GCCCGAGGTGACCGCGCCCCCGGTGCTGCTGTTGCTGCCGCCGGCCTCGGGCGCGGTGCCGGCGGTGTCCGTGGCGCAGT
CGCCTCCGGCGCGCGCGATGACGCGTCCGCCGGAGGCCGAGCGCCTGCTCGCTGCGCTGCAGGAGCACCGCTGGAACATC
ACCGCGGTGGCCGCGCAGGCCGGGCAGAACCGCACCACCATCTACCGGCAGATGAAGCGCTTCGGCATCGTCTCGCCCAC
GCAGCTGCCGCCCGAGGGCGAACGCTCCTAG

Upstream 100 bases:

>100_bases
TCGCGCAGCCGGACGCAGACGCCGGCATCAGGAGCCGTGAGCTCCTCGCACTGCGAGGCCACTCAACCACCGCCGTGCCG
ACTCTCAAGGAGCAGCCGAC

Downstream 100 bases:

>100_bases
CGGGCCCTGGCTAGAATCGCGGCTCCCACCCGTCATCGGGGAGTAGCCGCCCTGCATCCGTTGCAGGGGCTCGCGTCAAC
ACACTTGGCCTGCAGGCCAT

Product: transcriptional regulator AcoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MILSHQHVDEIRRIAAGHAPAAGTPDSLIHRSWHRCVNTHGLDPAQSFGPRVESPTRLRESRERIEEYLQVARGGMEQLF
KRVSDLGYVLLLTDADGVTVDYIGNDSWGKDAQRAGLYLGANWKEEIAGTNGIGTCIYEQAALTCHRDDHFYTGNVGLSC
NTAPLFHPDGKLMGVLDVSALAMPNARESQHLALHLTTLYGQMIEDANFVRHFRDHWILRLATSWALVDVLGDMMLAFDS
DGVLAGASTGARKWLSGLALQGGDDAPIEGRHLTDVFRCSMDDIWRLARSSNVMDRALLSAFDHQSYFGSVVAPRMRSAA
SSAAGPRDVTDAAPALAPASPALERLAGDDKQMRALQDQARRLANKRINILIQGETGTGKEVFAKALHESSTRHDKPFVA
VNCASIPESLIESELFGYTAGTFTGARSRGMKGLIVQAHGGTLFLDEIGDMPLHLQTRLLRVLSEHEVLPLGADRPIRVE
LTVIAASHRDLRQLIAAGSFREDLYYRLCGATLPLPALRDRRDLGYLIELILREEAEHLDTRAYIADEALELLERYEWPG
NVRQLRNVLRFGLALSDGEGIYPEHLPPEVTAPPVLLLLPPASGAVPAVSVAQSPPARAMTRPPEAERLLAALQEHRWNI
TAVAAQAGQNRTTIYRQMKRFGIVSPTQLPPEGERS

Sequences:

>Translated_676_residues
MILSHQHVDEIRRIAAGHAPAAGTPDSLIHRSWHRCVNTHGLDPAQSFGPRVESPTRLRESRERIEEYLQVARGGMEQLF
KRVSDLGYVLLLTDADGVTVDYIGNDSWGKDAQRAGLYLGANWKEEIAGTNGIGTCIYEQAALTCHRDDHFYTGNVGLSC
NTAPLFHPDGKLMGVLDVSALAMPNARESQHLALHLTTLYGQMIEDANFVRHFRDHWILRLATSWALVDVLGDMMLAFDS
DGVLAGASTGARKWLSGLALQGGDDAPIEGRHLTDVFRCSMDDIWRLARSSNVMDRALLSAFDHQSYFGSVVAPRMRSAA
SSAAGPRDVTDAAPALAPASPALERLAGDDKQMRALQDQARRLANKRINILIQGETGTGKEVFAKALHESSTRHDKPFVA
VNCASIPESLIESELFGYTAGTFTGARSRGMKGLIVQAHGGTLFLDEIGDMPLHLQTRLLRVLSEHEVLPLGADRPIRVE
LTVIAASHRDLRQLIAAGSFREDLYYRLCGATLPLPALRDRRDLGYLIELILREEAEHLDTRAYIADEALELLERYEWPG
NVRQLRNVLRFGLALSDGEGIYPEHLPPEVTAPPVLLLLPPASGAVPAVSVAQSPPARAMTRPPEAERLLAALQEHRWNI
TAVAAQAGQNRTTIYRQMKRFGIVSPTQLPPEGERS
>Mature_676_residues
MILSHQHVDEIRRIAAGHAPAAGTPDSLIHRSWHRCVNTHGLDPAQSFGPRVESPTRLRESRERIEEYLQVARGGMEQLF
KRVSDLGYVLLLTDADGVTVDYIGNDSWGKDAQRAGLYLGANWKEEIAGTNGIGTCIYEQAALTCHRDDHFYTGNVGLSC
NTAPLFHPDGKLMGVLDVSALAMPNARESQHLALHLTTLYGQMIEDANFVRHFRDHWILRLATSWALVDVLGDMMLAFDS
DGVLAGASTGARKWLSGLALQGGDDAPIEGRHLTDVFRCSMDDIWRLARSSNVMDRALLSAFDHQSYFGSVVAPRMRSAA
SSAAGPRDVTDAAPALAPASPALERLAGDDKQMRALQDQARRLANKRINILIQGETGTGKEVFAKALHESSTRHDKPFVA
VNCASIPESLIESELFGYTAGTFTGARSRGMKGLIVQAHGGTLFLDEIGDMPLHLQTRLLRVLSEHEVLPLGADRPIRVE
LTVIAASHRDLRQLIAAGSFREDLYYRLCGATLPLPALRDRRDLGYLIELILREEAEHLDTRAYIADEALELLERYEWPG
NVRQLRNVLRFGLALSDGEGIYPEHLPPEVTAPPVLLLLPPASGAVPAVSVAQSPPARAMTRPPEAERLLAALQEHRWNI
TAVAAQAGQNRTTIYRQMKRFGIVSPTQLPPEGERS

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=352, Percent_Identity=39.2045454545455, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1788905, Length=365, Percent_Identity=40.5479452054795, Blast_Score=229, Evalue=5e-61,
Organism=Escherichia coli, GI1788550, Length=320, Percent_Identity=38.75, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1790437, Length=318, Percent_Identity=40.251572327044, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI87082117, Length=369, Percent_Identity=40.1084010840108, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1786524, Length=329, Percent_Identity=42.2492401215805, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1790299, Length=324, Percent_Identity=41.0493827160494, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI87082152, Length=324, Percent_Identity=39.1975308641975, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789087, Length=326, Percent_Identity=36.8098159509202, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1787583, Length=324, Percent_Identity=35.8024691358025, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=37.9912663755458, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI87081858, Length=662, Percent_Identity=25.6797583081571, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1789828, Length=219, Percent_Identity=39.7260273972603, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74281; Mature: 74281

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSHQHVDEIRRIAAGHAPAAGTPDSLIHRSWHRCVNTHGLDPAQSFGPRVESPTRLRE
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHH
SRERIEEYLQVARGGMEQLFKRVSDLGYVLLLTDADGVTVDYIGNDSWGKDAQRAGLYLG
HHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCHHHCCEEEC
ANWKEEIAGTNGIGTCIYEQAALTCHRDDHFYTGNVGLSCNTAPLFHPDGKLMGVLDVSA
CCCHHHHCCCCCCHHHHHHHHHHEEECCCCEEECCCCCEECCCCCCCCCCCEEEEEEHHH
LAMPNARESQHLALHLTTLYGQMIEDANFVRHFRDHWILRLATSWALVDVLGDMMLAFDS
HCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGVLAGASTGARKWLSGLALQGGDDAPIEGRHLTDVFRCSMDDIWRLARSSNVMDRALLS
CCCEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHH
AFDHQSYFGSVVAPRMRSAASSAAGPRDVTDAAPALAPASPALERLAGDDKQMRALQDQA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHH
RRLANKRINILIQGETGTGKEVFAKALHESSTRHDKPFVAVNCASIPESLIESELFGYTA
HHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCC
GTFTGARSRGMKGLIVQAHGGTLFLDEIGDMPLHLQTRLLRVLSEHEVLPLGADRPIRVE
CCCCCHHHCCCCEEEEEECCCEEEEHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCEEEE
LTVIAASHRDLRQLIAAGSFREDLYYRLCGATLPLPALRDRRDLGYLIELILREEAEHLD
EEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
TRAYIADEALELLERYEWPGNVRQLRNVLRFGLALSDGEGIYPEHLPPEVTAPPVLLLLP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCEEEEEC
PASGAVPAVSVAQSPPARAMTRPPEAERLLAALQEHRWNITAVAAQAGQNRTTIYRQMKR
CCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHCCCCHHHHHHHHHH
FGIVSPTQLPPEGERS
HCCCCCCCCCCCCCCC
>Mature Secondary Structure
MILSHQHVDEIRRIAAGHAPAAGTPDSLIHRSWHRCVNTHGLDPAQSFGPRVESPTRLRE
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHH
SRERIEEYLQVARGGMEQLFKRVSDLGYVLLLTDADGVTVDYIGNDSWGKDAQRAGLYLG
HHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCEEEEECCCCCCCCHHHCCEEEC
ANWKEEIAGTNGIGTCIYEQAALTCHRDDHFYTGNVGLSCNTAPLFHPDGKLMGVLDVSA
CCCHHHHCCCCCCHHHHHHHHHHEEECCCCEEECCCCCEECCCCCCCCCCCEEEEEEHHH
LAMPNARESQHLALHLTTLYGQMIEDANFVRHFRDHWILRLATSWALVDVLGDMMLAFDS
HCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGVLAGASTGARKWLSGLALQGGDDAPIEGRHLTDVFRCSMDDIWRLARSSNVMDRALLS
CCCEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHH
AFDHQSYFGSVVAPRMRSAASSAAGPRDVTDAAPALAPASPALERLAGDDKQMRALQDQA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHH
RRLANKRINILIQGETGTGKEVFAKALHESSTRHDKPFVAVNCASIPESLIESELFGYTA
HHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCC
GTFTGARSRGMKGLIVQAHGGTLFLDEIGDMPLHLQTRLLRVLSEHEVLPLGADRPIRVE
CCCCCHHHCCCCEEEEEECCCEEEEHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCEEEE
LTVIAASHRDLRQLIAAGSFREDLYYRLCGATLPLPALRDRRDLGYLIELILREEAEHLD
EEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHH
TRAYIADEALELLERYEWPGNVRQLRNVLRFGLALSDGEGIYPEHLPPEVTAPPVLLLLP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCEEEEEC
PASGAVPAVSVAQSPPARAMTRPPEAERLLAALQEHRWNITAVAAQAGQNRTTIYRQMKR
CCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHCCCCHHHHHHHHHH
FGIVSPTQLPPEGERS
HCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]