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The map label for this gene is 124265351

Identifier: 124265351

GI number: 124265351

Start: 166142

End: 166852

Strand: Direct

Name: 124265351

Synonym: Mpe_A0158

Alternate gene names: NA

Gene position: 166142-166852 (Clockwise)

Preceding gene: 124265348

Following gene: 124265352

Centisome position: 4.11

GC content: 68.35

Gene sequence:

>711_bases
ATGAAGTCACCCAAGCCGTCCCTCTCCGTCCAAGCCGTGCTGTTCGACGCGTACGGCACGCTGTTCGACGTCTACAGCGT
CGGTACGCTGGCCGAGCAGCTGTTTCCCGGCCAGGGCGAGGCGCTGGCGGTGCTGTGGCGTGACAAGCAGATCGAGTACA
CGCGCCTGGTGTCGATGAGCCAGCGCTACCGGCCGTTCTGGGAGCTCACGCGCGCGGGGCTGCGCTACGCCTGCGCGCGG
CTGCAGCTCGACCTGACGCCGGAGCGCGAGACCCAGTTGCTCAACCAGTACCGCCACCTCGGTGCCTTTCCCGAGAACAA
GGCGGTGCTGACGGCGCTGAAGGCGCGCGGCGTGACCACCGGCATCCTCAGCAACGGCGACCCCGAGATGCTGGGCATCG
CGGTGCGCAGCGCCGGCTACGTGGACGACAAGGGCCAGGGCCTGCTCGACCACGTGCTCAGCGTCGAGAGCGTGCAGCGC
TTCAAGACCGACCCGGCCGCCTATGCGCTGGGCCCGCAGGCGCTGGGCATTCCGGCCCGGCAGATCCTGTTCGTTTCCAG
CAACGGCTGGGACGCGATCGGCGCGACTTGGTACGGTTACTGCACGCTGTGGGTGAACCGCTTCAAGCTGCCGCTCGAGG
CCCTCGACACCGAGCCGACGCGCACCGGCAGCAGCCTGCGCGACGTGCTCGACTTCTTTCCCAAGACCTGA

Upstream 100 bases:

>100_bases
ATGGGGCGGATTCGGGGCAGATTACTGATGCTTCAGTAAAAGATCAAGCGCAAATCGGTCGCTAAATGCGCACTCAGGTT
CGTAATAAAGTGGCCTCTCG

Downstream 100 bases:

>100_bases
AACTCCCTGTCCCTAGGAGCTGACCATGACGACCCTCCAACTGCCCGCCGGCCTGCAGATCAACGCGGCGATCCTGCCGG
GCTTCGAGACCATCCTCACG

Product: 2-haloacid dehalogenase

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase; Halocarboxylic acid halidohydrolase; L-2-haloacid dehalogenase; L-DEX [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKSPKPSLSVQAVLFDAYGTLFDVYSVGTLAEQLFPGQGEALAVLWRDKQIEYTRLVSMSQRYRPFWELTRAGLRYACAR
LQLDLTPERETQLLNQYRHLGAFPENKAVLTALKARGVTTGILSNGDPEMLGIAVRSAGYVDDKGQGLLDHVLSVESVQR
FKTDPAAYALGPQALGIPARQILFVSSNGWDAIGATWYGYCTLWVNRFKLPLEALDTEPTRTGSSLRDVLDFFPKT

Sequences:

>Translated_236_residues
MKSPKPSLSVQAVLFDAYGTLFDVYSVGTLAEQLFPGQGEALAVLWRDKQIEYTRLVSMSQRYRPFWELTRAGLRYACAR
LQLDLTPERETQLLNQYRHLGAFPENKAVLTALKARGVTTGILSNGDPEMLGIAVRSAGYVDDKGQGLLDHVLSVESVQR
FKTDPAAYALGPQALGIPARQILFVSSNGWDAIGATWYGYCTLWVNRFKLPLEALDTEPTRTGSSLRDVLDFFPKT
>Mature_236_residues
MKSPKPSLSVQAVLFDAYGTLFDVYSVGTLAEQLFPGQGEALAVLWRDKQIEYTRLVSMSQRYRPFWELTRAGLRYACAR
LQLDLTPERETQLLNQYRHLGAFPENKAVLTALKARGVTTGILSNGDPEMLGIAVRSAGYVDDKGQGLLDHVLSVESVQR
FKTDPAAYALGPQALGIPARQILFVSSNGWDAIGATWYGYCTLWVNRFKLPLEALDTEPTRTGSSLRDVLDFFPKT

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 26237; Mature: 26237

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSPKPSLSVQAVLFDAYGTLFDVYSVGTLAEQLFPGQGEALAVLWRDKQIEYTRLVSMS
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
QRYRPFWELTRAGLRYACARLQLDLTPERETQLLNQYRHLGAFPENKAVLTALKARGVTT
HHCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
GILSNGDPEMLGIAVRSAGYVDDKGQGLLDHVLSVESVQRFKTDPAAYALGPQALGIPAR
EECCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCHHCCCCCE
QILFVSSNGWDAIGATWYGYCTLWVNRFKLPLEALDTEPTRTGSSLRDVLDFFPKT
EEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKSPKPSLSVQAVLFDAYGTLFDVYSVGTLAEQLFPGQGEALAVLWRDKQIEYTRLVSMS
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
QRYRPFWELTRAGLRYACARLQLDLTPERETQLLNQYRHLGAFPENKAVLTALKARGVTT
HHCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
GILSNGDPEMLGIAVRSAGYVDDKGQGLLDHVLSVESVQRFKTDPAAYALGPQALGIPAR
EECCCCCCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCHHCCCCCE
QILFVSSNGWDAIGATWYGYCTLWVNRFKLPLEALDTEPTRTGSSLRDVLDFFPKT
EEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7944368; 7490277; 8702766; 9614112 [H]