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The map label for this gene is csd1 [H]

Identifier: 124265216

GI number: 124265216

Start: 24591

End: 26576

Strand: Reverse

Name: csd1 [H]

Synonym: Mpe_A0023

Alternate gene names: 124265216

Gene position: 26576-24591 (Counterclockwise)

Preceding gene: 124265217

Following gene: 124265215

Centisome position: 0.66

GC content: 73.51

Gene sequence:

>1986_bases
ATGTCCACGTCCGATGCCCTGAGCGGCCCGGTCGCGGCGGCGCAGCCCGCGTTGCCGCCCGGCCTGCCCGATCCCGCCAC
GCTCGCGCGTCTGGCGGGCGAATTCTTCGCCGCGCTGCCCGGCGACGGCGGCGCCCACGGCGGCGTGCCGGTGCCGGCAC
AGCCCACCCCGCCCGGCCTGTCGCTGCCCGGTGTGCTGACCGGCGGTCCGGCCACGCCCAACGTGCTGCCGCTCGGGGCC
GCGGCGCCCGGCGCCAACCTCGTGCCCAGCTCGCCCCAGCACGCCGCGGCGCACGGTGCGTCGGCCCCGGCGCTGGTGCC
GCATGCGGCCGCGCCGAACGGGCTGCCCGAGCACGTGGCCACCCTCCCGCCGACGCTCGATGGCCGCCTCGGCAGCCACG
CCCTCGGCGTGCCGCAGGTCGTGCCGGCCGCATCGCCGCTGGTCGGGCTGCCGTCGCACCCGTCGGCCGGCGGCGCACCC
GCGGCAACCGACACGCCATCGCCCTACTACTTCCTGTCGCACGCCACGTCCGGACCGGGCGCGAGCGAGGCGCGCATCGC
GCCGCTCGGCAGTGCACCGACCGGGCTACCGCAGGAGGCCGACCTGCGCTCGCTGCTGCGCAGCGACGCGCCGTCGTCCG
GCAGCGCCCCCGCGGCGTCGCCCGGCGCCTTCTACTTCCTCGACGCGCAGCGCCATCCCGGGCCGCACGGCAGCCACGCG
GGCGCCGTGCCGAACGCGGCGGCCTCGGCCCATCCGCCGTTCGACGTGCACGCGATCCGGCGCGACTTCCCGATCCTGCA
GGAGCGCGTCAACGGTCGCCCGCTCGTGTGGTTCGACAACGCCGCGACGACGCACAAGCCGCAGTCGGTGATCGACCGCA
TCGCCCATTTCTACGCGCACGAGAACTCCAACATCCACCGCGCCGCGCACGAGCTGGCGGCGCGCGCTACCGACGCCTAC
GAAGGCGCGCGCGAGACGGTGCGGCGCTTCATCGGCGCGAGCTCGGTGGAAGAGATCGTGTTCGTGCGCGGCACCACCGA
GGCCATCAACCTGGTGGCCAAGAGCTGGGGCGCGCAGAACATCGGTGCCGGCGACGAGATCGTGGTCTCGCACCTCGAGC
ACCACGCCAACATCGTGCCGTGGCAGCAGCTCGCCGCCGAGAAGGGCGCGAAGCTGCGCGTGATCCCGGTCGACGACAGC
GGCCAGGTGCGGCTCGACGAATACCGCAAGCTGCTGAACGACCGCACGAAGATCGTCTCGGTGACGCAGGTGTCCAACGC
GCTGGGCACCGTGGTGCCGGTGAAGGAGATCGTCGAGCTGGCGCACCGCGCCGGCGCGAAGGCGCTGGTCGACGGCGCGC
AGTCGGTCTCGCACCTGCGGGTGAACGTGCAGGCGCTCGACGCCGACTTCTTCGTGTTCTCCGGCCACAAGATCTTCGGT
CCCACCGGCATCGGCGTGGTCTACGGCAAGCGCGAGGTGCTCGAGGACATGCCCCCGTGGCAGGGCGGCGGCAACATGAT
CGCCGACGTGACTTTCGAGAAGACGGTCTACCACGGGCCGCCGACGCGCTTCGAGGCCGGCACCGGCAACATCGCCGACG
CGGTGGGCCTGGGCGCGGCGCTCGACTACGTGGAGCGCGTGGGCATCGAGAACATCGCGCGCTACGAGCACGACCTGCTC
GACTACGCGACGCACGCGCTGCGCCCGATCGCCGGCGTACGGCTGGTGGGCACCGCGCGCGACAAGGCCAGCGTGCTGTC
CTTCGTGCTCGACGGCTACACGACCGACGAGGTGGGCAAGGCGCTCAACGAGGAAGGCATCGCGGTGCGCACCGGCCACC
ACTGCGCCCAGCCCATCCTGCGCCGCTTCGGACTCGAGGCCACGGTGCGGCCCTCGCTGGCGTTCTACAACACCTGCGAG
GAAGTGGACCGCTTCATCGCGGTGGTGCGCCGGCTGAGCGGCGCGCGGCGCGTGCCGGCACGCTGA

Upstream 100 bases:

>100_bases
GCTGGCGGTGCAGACGCCCGACGCGCTGGCTGTGCTGGAGGACGTGGAGATCGGCAAGTACCACGACTATCCGGACACCT
ACAAGTAAGCAGGCGCCGCG

Downstream 100 bases:

>100_bases
CGGTCGGGCTTTTCCCGGCCGACGCAGAATCGGCTCCGGGTCACGCCGTCGCACCCCCTCGGGCGCGCGAGCCGGTGACC
GGGAGCCGAGATGTCCTACA

Product: putative cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MSTSDALSGPVAAAQPALPPGLPDPATLARLAGEFFAALPGDGGAHGGVPVPAQPTPPGLSLPGVLTGGPATPNVLPLGA
AAPGANLVPSSPQHAAAHGASAPALVPHAAAPNGLPEHVATLPPTLDGRLGSHALGVPQVVPAASPLVGLPSHPSAGGAP
AATDTPSPYYFLSHATSGPGASEARIAPLGSAPTGLPQEADLRSLLRSDAPSSGSAPAASPGAFYFLDAQRHPGPHGSHA
GAVPNAAASAHPPFDVHAIRRDFPILQERVNGRPLVWFDNAATTHKPQSVIDRIAHFYAHENSNIHRAAHELAARATDAY
EGARETVRRFIGASSVEEIVFVRGTTEAINLVAKSWGAQNIGAGDEIVVSHLEHHANIVPWQQLAAEKGAKLRVIPVDDS
GQVRLDEYRKLLNDRTKIVSVTQVSNALGTVVPVKEIVELAHRAGAKALVDGAQSVSHLRVNVQALDADFFVFSGHKIFG
PTGIGVVYGKREVLEDMPPWQGGGNMIADVTFEKTVYHGPPTRFEAGTGNIADAVGLGAALDYVERVGIENIARYEHDLL
DYATHALRPIAGVRLVGTARDKASVLSFVLDGYTTDEVGKALNEEGIAVRTGHHCAQPILRRFGLEATVRPSLAFYNTCE
EVDRFIAVVRRLSGARRVPAR

Sequences:

>Translated_661_residues
MSTSDALSGPVAAAQPALPPGLPDPATLARLAGEFFAALPGDGGAHGGVPVPAQPTPPGLSLPGVLTGGPATPNVLPLGA
AAPGANLVPSSPQHAAAHGASAPALVPHAAAPNGLPEHVATLPPTLDGRLGSHALGVPQVVPAASPLVGLPSHPSAGGAP
AATDTPSPYYFLSHATSGPGASEARIAPLGSAPTGLPQEADLRSLLRSDAPSSGSAPAASPGAFYFLDAQRHPGPHGSHA
GAVPNAAASAHPPFDVHAIRRDFPILQERVNGRPLVWFDNAATTHKPQSVIDRIAHFYAHENSNIHRAAHELAARATDAY
EGARETVRRFIGASSVEEIVFVRGTTEAINLVAKSWGAQNIGAGDEIVVSHLEHHANIVPWQQLAAEKGAKLRVIPVDDS
GQVRLDEYRKLLNDRTKIVSVTQVSNALGTVVPVKEIVELAHRAGAKALVDGAQSVSHLRVNVQALDADFFVFSGHKIFG
PTGIGVVYGKREVLEDMPPWQGGGNMIADVTFEKTVYHGPPTRFEAGTGNIADAVGLGAALDYVERVGIENIARYEHDLL
DYATHALRPIAGVRLVGTARDKASVLSFVLDGYTTDEVGKALNEEGIAVRTGHHCAQPILRRFGLEATVRPSLAFYNTCE
EVDRFIAVVRRLSGARRVPAR
>Mature_660_residues
STSDALSGPVAAAQPALPPGLPDPATLARLAGEFFAALPGDGGAHGGVPVPAQPTPPGLSLPGVLTGGPATPNVLPLGAA
APGANLVPSSPQHAAAHGASAPALVPHAAAPNGLPEHVATLPPTLDGRLGSHALGVPQVVPAASPLVGLPSHPSAGGAPA
ATDTPSPYYFLSHATSGPGASEARIAPLGSAPTGLPQEADLRSLLRSDAPSSGSAPAASPGAFYFLDAQRHPGPHGSHAG
AVPNAAASAHPPFDVHAIRRDFPILQERVNGRPLVWFDNAATTHKPQSVIDRIAHFYAHENSNIHRAAHELAARATDAYE
GARETVRRFIGASSVEEIVFVRGTTEAINLVAKSWGAQNIGAGDEIVVSHLEHHANIVPWQQLAAEKGAKLRVIPVDDSG
QVRLDEYRKLLNDRTKIVSVTQVSNALGTVVPVKEIVELAHRAGAKALVDGAQSVSHLRVNVQALDADFFVFSGHKIFGP
TGIGVVYGKREVLEDMPPWQGGGNMIADVTFEKTVYHGPPTRFEAGTGNIADAVGLGAALDYVERVGIENIARYEHDLLD
YATHALRPIAGVRLVGTARDKASVLSFVLDGYTTDEVGKALNEEGIAVRTGHHCAQPILRRFGLEATVRPSLAFYNTCEE
VDRFIAVVRRLSGARRVPAR

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=274, Percent_Identity=28.8321167883212, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI156713448, Length=295, Percent_Identity=28.4745762711864, Blast_Score=85, Evalue=3e-16,
Organism=Escherichia coli, GI1787970, Length=400, Percent_Identity=50.75, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1789175, Length=398, Percent_Identity=39.6984924623116, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI48994898, Length=402, Percent_Identity=28.3582089552239, Blast_Score=112, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI25143064, Length=216, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=382, Percent_Identity=25.9162303664921, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=232, Percent_Identity=30.1724137931034, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20129463, Length=430, Percent_Identity=27.4418604651163, Blast_Score=113, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 68830; Mature: 68699

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSDALSGPVAAAQPALPPGLPDPATLARLAGEFFAALPGDGGAHGGVPVPAQPTPPGL
CCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SLPGVLTGGPATPNVLPLGAAAPGANLVPSSPQHAAAHGASAPALVPHAAAPNGLPEHVA
CCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHH
TLPPTLDGRLGSHALGVPQVVPAASPLVGLPSHPSAGGAPAATDTPSPYYFLSHATSGPG
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
ASEARIAPLGSAPTGLPQEADLRSLLRSDAPSSGSAPAASPGAFYFLDAQRHPGPHGSHA
CCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
GAVPNAAASAHPPFDVHAIRRDFPILQERVNGRPLVWFDNAATTHKPQSVIDRIAHFYAH
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHC
ENSNIHRAAHELAARATDAYEGARETVRRFIGASSVEEIVFVRGTTEAINLVAKSWGAQN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCC
IGAGDEIVVSHLEHHANIVPWQQLAAEKGAKLRVIPVDDSGQVRLDEYRKLLNDRTKIVS
CCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHCCHHHEEE
VTQVSNALGTVVPVKEIVELAHRAGAKALVDGAQSVSHLRVNVQALDADFFVFSGHKIFG
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEEECCEEEEEECCEEEC
PTGIGVVYGKREVLEDMPPWQGGGNMIADVTFEKTVYHGPPTRFEAGTGNIADAVGLGAA
CCCCEEEECCHHHHHCCCCCCCCCCEEEEEEEECEEECCCCCCCCCCCCCHHHHHHHHHH
LDYVERVGIENIARYEHDLLDYATHALRPIAGVRLVGTARDKASVLSFVLDGYTTDEVGK
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCHHHHHH
ALNEEGIAVRTGHHCAQPILRRFGLEATVRPSLAFYNTCEEVDRFIAVVRRLSGARRVPA
HHCCCCCEEECCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
R
C
>Mature Secondary Structure 
STSDALSGPVAAAQPALPPGLPDPATLARLAGEFFAALPGDGGAHGGVPVPAQPTPPGL
CCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SLPGVLTGGPATPNVLPLGAAAPGANLVPSSPQHAAAHGASAPALVPHAAAPNGLPEHVA
CCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHH
TLPPTLDGRLGSHALGVPQVVPAASPLVGLPSHPSAGGAPAATDTPSPYYFLSHATSGPG
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
ASEARIAPLGSAPTGLPQEADLRSLLRSDAPSSGSAPAASPGAFYFLDAQRHPGPHGSHA
CCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
GAVPNAAASAHPPFDVHAIRRDFPILQERVNGRPLVWFDNAATTHKPQSVIDRIAHFYAH
CCCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHC
ENSNIHRAAHELAARATDAYEGARETVRRFIGASSVEEIVFVRGTTEAINLVAKSWGAQN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCCCCC
IGAGDEIVVSHLEHHANIVPWQQLAAEKGAKLRVIPVDDSGQVRLDEYRKLLNDRTKIVS
CCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHCCHHHEEE
VTQVSNALGTVVPVKEIVELAHRAGAKALVDGAQSVSHLRVNVQALDADFFVFSGHKIFG
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEEECCEEEEEECCEEEC
PTGIGVVYGKREVLEDMPPWQGGGNMIADVTFEKTVYHGPPTRFEAGTGNIADAVGLGAA
CCCCEEEECCHHHHHCCCCCCCCCCEEEEEEEECEEECCCCCCCCCCCCCHHHHHHHHHH
LDYVERVGIENIARYEHDLLDYATHALRPIAGVRLVGTARDKASVLSFVLDGYTTDEVGK
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCHHHHHH
ALNEEGIAVRTGHHCAQPILRRFGLEATVRPSLAFYNTCEEVDRFIAVVRRLSGARRVPA
HHCCCCCEEECCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]