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The map label for this gene is bioD [H]

Identifier: 124022166

GI number: 124022166

Start: 457341

End: 458039

Strand: Reverse

Name: bioD [H]

Synonym: P9303_04561

Alternate gene names: 124022166

Gene position: 458039-457341 (Counterclockwise)

Preceding gene: 124022167

Following gene: 124022165

Centisome position: 17.07

GC content: 53.51

Gene sequence:

>699_bases
ATGGCTGATCCAACTGCTTTTAATCCAGCGATGACTGAGGCAAAGACTCCTCTAATCGTCTGCGGCACAGACACCAACGT
CGGCAAGACCGTGGTGAGTGCATTGCTAGTGCAAGGATTAGTTGCCACCTACTGGAAGCCAATCCAAAGCGGCCTAGAGG
AAGACGGTGGAGACCGCAATAGGGTTTGTCAACTCCTTAACCTTCCCGCCGAACGTTGGCACCCAGAGGTCTATAACCTC
CAGGCCGCAGTATCACCCCACTGGGCCGCAGAACAAGAGAACTGCTGCATCAACCCCGATCAACTTGTATTGCCTGATCT
ATCTGGTCCCCTAGTGATAGAAACTGCTGGCGGCCTAATGGTGCCACTCAACCGTCAATGGCTACAACTCGATCAACTCG
TGCGTTGGCAACTACCGCTCATCCTCGTTGCACGCAGTGGCCTGGGTACCCTCAACCACACCCTGCTCAGCCTTGAAGCA
CTGCGCTTGCGCAATCTGAAGGTCTTAGGTTTGGTGCTCAATGGTCCACCCCACCCCGACAATCCAAAAACCCTGGAACA
ATTTGGTGGTGTTCCAGTCATCGCTCAGTTGCCTCACTTACCCAATCTCACGGCAGCAACACTCGCAGAGCAGTGGCATC
TGCAAGACCTGAGCCTTACCTTCAAACGGCTACTGAAATCCTGGAGTCAAGTTCAATGA

Upstream 100 bases:

>100_bases
GTGCCCAGGCCAGCCCTTGCCCAAGCATGGGGGTTGGCAACTGGCGCCATCTCAAACAAGCCTGGCCACGTTGCCAGAAC
AGTGGAGATGCACAACTCAC

Downstream 100 bases:

>100_bases
ACAAGCGTCAGTCATGGGCCACAGTTGGAGTTGTTCTTCTCTGTGGAGGAATCCTTGTGCTATTCACCGACATTGAAGTC
GGCATGGTGCGCTGGGTCAA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MADPTAFNPAMTEAKTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCQLLNLPAERWHPEVYNL
QAAVSPHWAAEQENCCINPDQLVLPDLSGPLVIETAGGLMVPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEA
LRLRNLKVLGLVLNGPPHPDNPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ

Sequences:

>Translated_232_residues
MADPTAFNPAMTEAKTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCQLLNLPAERWHPEVYNL
QAAVSPHWAAEQENCCINPDQLVLPDLSGPLVIETAGGLMVPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEA
LRLRNLKVLGLVLNGPPHPDNPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ
>Mature_231_residues
ADPTAFNPAMTEAKTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCQLLNLPAERWHPEVYNLQ
AAVSPHWAAEQENCCINPDQLVLPDLSGPLVIETAGGLMVPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEAL
RLRNLKVLGLVLNGPPHPDNPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=202, Percent_Identity=29.7029702970297, Blast_Score=68, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324385, Length=197, Percent_Identity=40.1015228426396, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 25506; Mature: 25375

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPTAFNPAMTEAKTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRN
CCCCCCCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RVCQLLNLPAERWHPEVYNLQAAVSPHWAAEQENCCINPDQLVLPDLSGPLVIETAGGLM
HHHHHHCCCHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCEE
VPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEALRLRNLKVLGLVLNGPPHPD
EECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCC
NPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ
CCHHHHHHCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADPTAFNPAMTEAKTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRN
CCCCCCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RVCQLLNLPAERWHPEVYNLQAAVSPHWAAEQENCCINPDQLVLPDLSGPLVIETAGGLM
HHHHHHCCCHHHCCCHHHEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCCEE
VPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEALRLRNLKVLGLVLNGPPHPD
EECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCC
NPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ
CCHHHHHHCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA