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The map label for this gene is gadB [H]

Identifier: 124025483

GI number: 124025483

Start: 708551

End: 709921

Strand: Direct

Name: gadB [H]

Synonym: NATL1_07761

Alternate gene names: 124025483

Gene position: 708551-709921 (Clockwise)

Preceding gene: 124025481

Following gene: 124025487

Centisome position: 38.0

GC content: 35.89

Gene sequence:

>1371_bases
TTGGACCCTTTTGCTTCTCCTCAAAACTTAGATAAAGAACTGCGTTCTTTACTTGCTCAAGTCTCAAGTAATCTTTGTGA
TTGGTTTGCTGAATCAGCCAGTAAAGGTCCAATGCCCTATTCATTTGAATTGCCAGAGGTCTATCCAGCAAAAGAAGGTG
TTTCTAATGATGTTTTACTGAGTGAACTTCAATTACTAATGGATGGTTCCTATCGACCATCGCATCCAGGATCTCTTGCT
CATTTGGACCCACCTCCTCTATCAGCTTCAATAGCAGGAGAACTAATTTGTGCAGGTTTAAATAATAATCTTTTAGCCGA
TGAGCTATCCCCTAGCTTGTCTTCCTTGGAGAGAAACTTATGTAAATGGTTTTGTCACAAGCTTGGTCTTGGTGATTTGT
CTGGAGGTGTAGCGGCTAGCGGTGGGAGTTTGAGTAATTTAATGGCTTTAGTAATGGCAAGAAATAATTCTGGGCTAGAA
ACTGATCCTAAGGCTGTTTTTTTTGCAAGTCATGATTGTCATGTTTCATTCTCAAAAGCTTTTAGGATTATGGGGCTGAA
ACAGGAATCTCTACAAAAAGTTTCTACAGATGAAAATGGTGCATTAAATATTTCTAGTTTAAGAACAAGTTTAAATAAAA
TAAAATCTCAGGGTAAGAAATGCTTTGCTGTCGTAGCGACAGCTGGAACCACTGTAAGAGGGGCTATTGACCCACTTTCT
GAGATCGCTAAATTTTGTAAAAAAGAGAATGTTTGGTTTCATGTTGATGGCTCAATTGGTGGTATTTATGGTTTATCAGA
AATGACTTCAGAAATTGTTCAAGGCTTAGGTTTCGCTGACTCTTTAACTATTAATCCACAGAAATTATTGGGAATCCCAA
AAACTTCTTCTTTATTACTCGTAGCCAATAAAAACCATCTTTCTTCTACATTTTCAACCGGACTCCCTTATGTCGAACCA
ATTTCAGGAAATGACTTTCATGGAGGAGAGCTTGGAATCCAAGGTACTAGATCCGCAGAGACATTGAAATTGTGGATTGG
ATTAAGACAATTGGGTGAAGAGGGTATTGAAAAAATACTTTTGGGCTCAATTAAAAGAAGATGTTATTTAGAATCTATAA
TTGACCGATCAAAATTTAAAATAATATCAGGACCTCTTCATCTTTTAGCTTTTACACCTATTAATTATAGTTCTTCTCAA
GCATCCGATTGGTCTCTAAAAACAAGAAATTTTTTGTTAGCTAATAAGTTTATGCTCTCTAGGCCAATGTATGGAGATAG
ATATTATTTAAAAGCTGTTATGGGGAACCCTAATACTAAATTTGATGATTTAAAAATGTTGGCTAATCTTATTAATCATT
CAATTAGTTGA

Upstream 100 bases:

>100_bases
TAGATGTTTGGTGAACTATCAAATAAAATGTTTATCTAGAGATTAATCATTTTTTGGCTTGAACTGGATCATCCAATACT
ACAAATAGAGTTTTTTTTCT

Downstream 100 bases:

>100_bases
ATCTAATTATGAATAAGGATTTTTTTAATAAAAAAAATATATTGGCTTTAATAACAGCTTTAATATCAATTTTCGTTGGC
CTAATTTATTTAGCATTAGT

Product: pyridoxal-dependent decarboxylase family protein

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MDPFASPQNLDKELRSLLAQVSSNLCDWFAESASKGPMPYSFELPEVYPAKEGVSNDVLLSELQLLMDGSYRPSHPGSLA
HLDPPPLSASIAGELICAGLNNNLLADELSPSLSSLERNLCKWFCHKLGLGDLSGGVAASGGSLSNLMALVMARNNSGLE
TDPKAVFFASHDCHVSFSKAFRIMGLKQESLQKVSTDENGALNISSLRTSLNKIKSQGKKCFAVVATAGTTVRGAIDPLS
EIAKFCKKENVWFHVDGSIGGIYGLSEMTSEIVQGLGFADSLTINPQKLLGIPKTSSLLLVANKNHLSSTFSTGLPYVEP
ISGNDFHGGELGIQGTRSAETLKLWIGLRQLGEEGIEKILLGSIKRRCYLESIIDRSKFKIISGPLHLLAFTPINYSSSQ
ASDWSLKTRNFLLANKFMLSRPMYGDRYYLKAVMGNPNTKFDDLKMLANLINHSIS

Sequences:

>Translated_456_residues
MDPFASPQNLDKELRSLLAQVSSNLCDWFAESASKGPMPYSFELPEVYPAKEGVSNDVLLSELQLLMDGSYRPSHPGSLA
HLDPPPLSASIAGELICAGLNNNLLADELSPSLSSLERNLCKWFCHKLGLGDLSGGVAASGGSLSNLMALVMARNNSGLE
TDPKAVFFASHDCHVSFSKAFRIMGLKQESLQKVSTDENGALNISSLRTSLNKIKSQGKKCFAVVATAGTTVRGAIDPLS
EIAKFCKKENVWFHVDGSIGGIYGLSEMTSEIVQGLGFADSLTINPQKLLGIPKTSSLLLVANKNHLSSTFSTGLPYVEP
ISGNDFHGGELGIQGTRSAETLKLWIGLRQLGEEGIEKILLGSIKRRCYLESIIDRSKFKIISGPLHLLAFTPINYSSSQ
ASDWSLKTRNFLLANKFMLSRPMYGDRYYLKAVMGNPNTKFDDLKMLANLINHSIS
>Mature_456_residues
MDPFASPQNLDKELRSLLAQVSSNLCDWFAESASKGPMPYSFELPEVYPAKEGVSNDVLLSELQLLMDGSYRPSHPGSLA
HLDPPPLSASIAGELICAGLNNNLLADELSPSLSSLERNLCKWFCHKLGLGDLSGGVAASGGSLSNLMALVMARNNSGLE
TDPKAVFFASHDCHVSFSKAFRIMGLKQESLQKVSTDENGALNISSLRTSLNKIKSQGKKCFAVVATAGTTVRGAIDPLS
EIAKFCKKENVWFHVDGSIGGIYGLSEMTSEIVQGLGFADSLTINPQKLLGIPKTSSLLLVANKNHLSSTFSTGLPYVEP
ISGNDFHGGELGIQGTRSAETLKLWIGLRQLGEEGIEKILLGSIKRRCYLESIIDRSKFKIISGPLHLLAFTPINYSSSQ
ASDWSLKTRNFLLANKFMLSRPMYGDRYYLKAVMGNPNTKFDDLKMLANLINHSIS

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI194294551, Length=381, Percent_Identity=28.6089238845144, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI197383062, Length=408, Percent_Identity=26.9607843137255, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI197276620, Length=341, Percent_Identity=28.7390029325513, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI4503875, Length=341, Percent_Identity=28.7390029325513, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI58331246, Length=323, Percent_Identity=28.7925696594427, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI92110055, Length=358, Percent_Identity=27.3743016759777, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4503281, Length=364, Percent_Identity=24.4505494505494, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI132814448, Length=364, Percent_Identity=24.4505494505494, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI31982936, Length=293, Percent_Identity=25.5972696245734, Blast_Score=70, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555682, Length=303, Percent_Identity=28.7128712871287, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71993062, Length=303, Percent_Identity=28.7128712871287, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71993058, Length=303, Percent_Identity=28.7128712871287, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17534817, Length=414, Percent_Identity=22.7053140096618, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534819, Length=414, Percent_Identity=22.7053140096618, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981211, Length=357, Percent_Identity=21.2885154061625, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71981217, Length=201, Percent_Identity=23.3830845771144, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17136594, Length=348, Percent_Identity=28.448275862069, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21356415, Length=314, Percent_Identity=28.9808917197452, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24657193, Length=374, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24657185, Length=374, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24657188, Length=374, Percent_Identity=29.4117647058824, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573972, Length=369, Percent_Identity=27.10027100271, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24652373, Length=361, Percent_Identity=24.9307479224377, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24586044, Length=362, Percent_Identity=24.0331491712707, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17136190, Length=443, Percent_Identity=22.5733634311512, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24585135, Length=441, Percent_Identity=23.1292517006803, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24585139, Length=353, Percent_Identity=24.6458923512748, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221476190, Length=353, Percent_Identity=24.6458923512748, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24585143, Length=353, Percent_Identity=24.6458923512748, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 49468; Mature: 49468

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPFASPQNLDKELRSLLAQVSSNLCDWFAESASKGPMPYSFELPEVYPAKEGVSNDVLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCHHHH
SELQLLMDGSYRPSHPGSLAHLDPPPLSASIAGELICAGLNNNLLADELSPSLSSLERNL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCEEHHHCCHHHHHHHHHH
CKWFCHKLGLGDLSGGVAASGGSLSNLMALVMARNNSGLETDPKAVFFASHDCHVSFSKA
HHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEHHHH
FRIMGLKQESLQKVSTDENGALNISSLRTSLNKIKSQGKKCFAVVATAGTTVRGAIDPLS
HHHHCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEEECCCEEHHHHHHHH
EIAKFCKKENVWFHVDGSIGGIYGLSEMTSEIVQGLGFADSLTINPQKLLGIPKTSSLLL
HHHHHHHHCCCEEEECCCCCCHHCHHHHHHHHHHHCCCCCCEEECHHHHCCCCCCCCEEE
VANKNHLSSTFSTGLPYVEPISGNDFHGGELGIQGTRSAETLKLWIGLRQLGEEGIEKIL
EECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGSIKRRCYLESIIDRSKFKIISGPLHLLAFTPINYSSSQASDWSLKTRNFLLANKFMLS
HHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCHHCHHHHHHHHHHC
RPMYGDRYYLKAVMGNPNTKFDDLKMLANLINHSIS
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDPFASPQNLDKELRSLLAQVSSNLCDWFAESASKGPMPYSFELPEVYPAKEGVSNDVLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCHHHH
SELQLLMDGSYRPSHPGSLAHLDPPPLSASIAGELICAGLNNNLLADELSPSLSSLERNL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCCEEHHHCCHHHHHHHHHH
CKWFCHKLGLGDLSGGVAASGGSLSNLMALVMARNNSGLETDPKAVFFASHDCHVSFSKA
HHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEHHHH
FRIMGLKQESLQKVSTDENGALNISSLRTSLNKIKSQGKKCFAVVATAGTTVRGAIDPLS
HHHHCCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEEEECCCEEHHHHHHHH
EIAKFCKKENVWFHVDGSIGGIYGLSEMTSEIVQGLGFADSLTINPQKLLGIPKTSSLLL
HHHHHHHHCCCEEEECCCCCCHHCHHHHHHHHHHHCCCCCCEEECHHHHCCCCCCCCEEE
VANKNHLSSTFSTGLPYVEPISGNDFHGGELGIQGTRSAETLKLWIGLRQLGEEGIEKIL
EECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGSIKRRCYLESIIDRSKFKIISGPLHLLAFTPINYSSSQASDWSLKTRNFLLANKFMLS
HHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCHHCHHHHHHHHHHC
RPMYGDRYYLKAVMGNPNTKFDDLKMLANLINHSIS
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]