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The map label for this gene is aspC [H]

Identifier: 124025438

GI number: 124025438

Start: 673880

End: 675058

Strand: Reverse

Name: aspC [H]

Synonym: NATL1_07311

Alternate gene names: 124025438

Gene position: 675058-673880 (Counterclockwise)

Preceding gene: 124025442

Following gene: 124025437

Centisome position: 36.2

GC content: 35.45

Gene sequence:

>1179_bases
ATGACTGACAAATCACAGATATCTATAAGAGCTCTCTCCATAAAACCCTCTCTAACTCTTGAGATCAGCGCAAAAGCTAA
AGCTTTAAAAGCTGAAGGTAAAAATATTTGTAGTTTAAGCGCAGGGGAACCTGATTTCGATACCCCTGAATTTATTGTCG
ATGCAACTCTAAAAGCATTAAAAGATGGGAAAACTCGTTATGGGCCTGCAGCTGGAGATCCTGAATTAAGAGAAGCCATT
GCGCAAAAACAATCAGATATAAATAAAGTTCCAACAAAAACAGACAATGTTCTAGTAACCAATGGAGGTAAACAAGCAAT
ATACAATTTATTTCAAGTAGTTTTGAATCCCGGAGATGAAGTCCTGATACCAACTCCTTATTGGCTTAGTTATCCAGAGA
TAACTCTTTTAGCGGGTGCCAAGCCAATAAAAATTAAATCATCAACTAAAGATAAATTTAAAATAGATATCAATTCTCTA
GAAGAACACGTAACCGCAAAAACAAGGTTATTAATTATCAACTCTCCAAGTAATCCAACTGGCTGTGTTTTAACTGAGCA
AGAGATGAAAACTATTTCCGATTTTTTAAGAAGGCATCCAAGAATTTTATTAATGAGTGATGAAATTTATGAATTTCTTA
TTTCTCCAAATCAAGTTCATCACAGTTTCGCGAAAATCGCACCAGACCTAAAAAATAGAATTTTCACCGTCAACGGTTTT
GCCAAGGCGTGGGCAATGACTGGTTGGAGGATTGGCTACTTAACAGGAAACGCCGAGGTAATAAAGAAAGCCATTGCTTT
ACAAAGTCAAAGTACAAGCAATGTATGTAGTTTTGCTCAAAAAGGGGCTATTGCAGCACTTCAAGGCTCAAAAGATTGCG
TTCATGAAATGGCAAATATTTATAACAAAAGGAGGTTATTAATAACAGAAAGACTAAAAAAAATAAAACATATTTCTTTT
GTCCCTCCCAATGGAGCTTTCTATGTTTTCCCAGAAATTAATCTAGAGGAGATCGATTCAATAAGTTTCTGCAAATTGGC
ACTAGAAAAGGTCGGTCTAGCAATAGTGCCAGGAATTGCTTTCGGTGATGACAAATGTATAAGAATCTCATACGCAGCTT
CAAATAAAATGATCGAAGATGGAGTTAATAGGCTAGAAAGACTATTAAATGATTTTTAG

Upstream 100 bases:

>100_bases
CAAAGGCATGCAAGTATCTGATTAAGTAGTAAGTTTATAATTAGATGAATTCACTTTAAAAGTGAATCTAATAAAAACAT
TTTGAAGTTATGCTTCGAAG

Downstream 100 bases:

>100_bases
AAAGAATGGATCAAAAGCCAAGAGGAATAAAACTTATAAAAATAGCTTTTGCAGTTTTATCACTATCTAATTTATTTTCT
ATTGGTTCATTAAAAGCAGA

Product: aminotransferases class-I

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTDKSQISIRALSIKPSLTLEISAKAKALKAEGKNICSLSAGEPDFDTPEFIVDATLKALKDGKTRYGPAAGDPELREAI
AQKQSDINKVPTKTDNVLVTNGGKQAIYNLFQVVLNPGDEVLIPTPYWLSYPEITLLAGAKPIKIKSSTKDKFKIDINSL
EEHVTAKTRLLIINSPSNPTGCVLTEQEMKTISDFLRRHPRILLMSDEIYEFLISPNQVHHSFAKIAPDLKNRIFTVNGF
AKAWAMTGWRIGYLTGNAEVIKKAIALQSQSTSNVCSFAQKGAIAALQGSKDCVHEMANIYNKRRLLITERLKKIKHISF
VPPNGAFYVFPEINLEEIDSISFCKLALEKVGLAIVPGIAFGDDKCIRISYAASNKMIEDGVNRLERLLNDF

Sequences:

>Translated_392_residues
MTDKSQISIRALSIKPSLTLEISAKAKALKAEGKNICSLSAGEPDFDTPEFIVDATLKALKDGKTRYGPAAGDPELREAI
AQKQSDINKVPTKTDNVLVTNGGKQAIYNLFQVVLNPGDEVLIPTPYWLSYPEITLLAGAKPIKIKSSTKDKFKIDINSL
EEHVTAKTRLLIINSPSNPTGCVLTEQEMKTISDFLRRHPRILLMSDEIYEFLISPNQVHHSFAKIAPDLKNRIFTVNGF
AKAWAMTGWRIGYLTGNAEVIKKAIALQSQSTSNVCSFAQKGAIAALQGSKDCVHEMANIYNKRRLLITERLKKIKHISF
VPPNGAFYVFPEINLEEIDSISFCKLALEKVGLAIVPGIAFGDDKCIRISYAASNKMIEDGVNRLERLLNDF
>Mature_391_residues
TDKSQISIRALSIKPSLTLEISAKAKALKAEGKNICSLSAGEPDFDTPEFIVDATLKALKDGKTRYGPAAGDPELREAIA
QKQSDINKVPTKTDNVLVTNGGKQAIYNLFQVVLNPGDEVLIPTPYWLSYPEITLLAGAKPIKIKSSTKDKFKIDINSLE
EHVTAKTRLLIINSPSNPTGCVLTEQEMKTISDFLRRHPRILLMSDEIYEFLISPNQVHHSFAKIAPDLKNRIFTVNGFA
KAWAMTGWRIGYLTGNAEVIKKAIALQSQSTSNVCSFAQKGAIAALQGSKDCVHEMANIYNKRRLLITERLKKIKHISFV
PPNGAFYVFPEINLEEIDSISFCKLALEKVGLAIVPGIAFGDDKCIRISYAASNKMIEDGVNRLERLLNDF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=359, Percent_Identity=22.8412256267409, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI169881279, Length=359, Percent_Identity=22.8412256267409, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI56713254, Length=272, Percent_Identity=29.0441176470588, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI56713256, Length=272, Percent_Identity=29.0441176470588, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=25.6, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI169881281, Length=266, Percent_Identity=19.9248120300752, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI149944424, Length=318, Percent_Identity=25.7861635220126, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7705897, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33469970, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI215599424, Length=370, Percent_Identity=22.7027027027027, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI19263340, Length=371, Percent_Identity=22.6415094339623, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI187936925, Length=294, Percent_Identity=25.8503401360544, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14211921, Length=294, Percent_Identity=25.8503401360544, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=27.1052631578947, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788627, Length=351, Percent_Identity=26.7806267806268, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=27.0618556701031, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790797, Length=361, Percent_Identity=23.8227146814404, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=332, Percent_Identity=27.4096385542169, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=400, Percent_Identity=25.5, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=400, Percent_Identity=25.5, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=329, Percent_Identity=28.8753799392097, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=340, Percent_Identity=25.2941176470588, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=405, Percent_Identity=25.679012345679, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321236, Length=304, Percent_Identity=23.6842105263158, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28573069, Length=263, Percent_Identity=25.4752851711027, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646114, Length=263, Percent_Identity=25.4752851711027, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573067, Length=263, Percent_Identity=25.4752851711027, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573065, Length=263, Percent_Identity=25.4752851711027, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=22.7748691099476, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43337; Mature: 43205

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKSQISIRALSIKPSLTLEISAKAKALKAEGKNICSLSAGEPDFDTPEFIVDATLKAL
CCCCCEEEEEEEEECCCEEEEECCCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
KDGKTRYGPAAGDPELREAIAQKQSDINKVPTKTDNVLVTNGGKQAIYNLFQVVLNPGDE
HCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
VLIPTPYWLSYPEITLLAGAKPIKIKSSTKDKFKIDINSLEEHVTAKTRLLIINSPSNPT
EEECCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHHCCEEEEEEEECCCCCC
GCVLTEQEMKTISDFLRRHPRILLMSDEIYEFLISPNQVHHSFAKIAPDLKNRIFTVNGF
CEEEEHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCHHHHHHHHHCHHHHCCEEEEECH
AKAWAMTGWRIGYLTGNAEVIKKAIALQSQSTSNVCSFAQKGAIAALQGSKDCVHEMANI
HHHHHCCCEEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHH
YNKRRLLITERLKKIKHISFVPPNGAFYVFPEINLEEIDSISFCKLALEKVGLAIVPGIA
HHCCCHHHHHHHHHHHHEEEECCCCCEEEEECCCHHHHCCHHHHHHHHHHCCEEEECCEE
FGDDKCIRISYAASNKMIEDGVNRLERLLNDF
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDKSQISIRALSIKPSLTLEISAKAKALKAEGKNICSLSAGEPDFDTPEFIVDATLKAL
CCCCEEEEEEEEECCCEEEEECCCHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHH
KDGKTRYGPAAGDPELREAIAQKQSDINKVPTKTDNVLVTNGGKQAIYNLFQVVLNPGDE
HCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
VLIPTPYWLSYPEITLLAGAKPIKIKSSTKDKFKIDINSLEEHVTAKTRLLIINSPSNPT
EEECCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHHCCEEEEEEEECCCCCC
GCVLTEQEMKTISDFLRRHPRILLMSDEIYEFLISPNQVHHSFAKIAPDLKNRIFTVNGF
CEEEEHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCHHHHHHHHHCHHHHCCEEEEECH
AKAWAMTGWRIGYLTGNAEVIKKAIALQSQSTSNVCSFAQKGAIAALQGSKDCVHEMANI
HHHHHCCCEEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHH
YNKRRLLITERLKKIKHISFVPPNGAFYVFPEINLEEIDSISFCKLALEKVGLAIVPGIA
HHCCCHHHHHHHHHHHHEEEECCCCCEEEEECCCHHHHCCHHHHHHHHHHCCEEEECCEE
FGDDKCIRISYAASNKMIEDGVNRLERLLNDF
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]