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The map label for this gene is minD [H]

Identifier: 124025126

GI number: 124025126

Start: 378256

End: 379071

Strand: Reverse

Name: minD [H]

Synonym: NATL1_04131

Alternate gene names: 124025126

Gene position: 379071-378256 (Counterclockwise)

Preceding gene: 124025127

Following gene: 124025125

Centisome position: 20.33

GC content: 39.22

Gene sequence:

>816_bases
GTGGCGACAGATACACGAGTCATTCTTATTTGCTCAGGAAAGGGTGGGGTTGGTAAGACAACCCTGACAGCTAATCTTGG
CATTTCATTAGCAAGGCAGGGGTTAACCACTGCTGTTTTAGACGCAGACTTTGGTCTGAGAAATTTGGATTTACTATTAG
GTCTTGAAAATCGAATTGTATATACGGCTCAAGAAGTTCTAGAGGAAGAATGCAGACTTGATCAGGCCTTAGTGAAGCAC
AAGCAAGAATCCAATCTATCTTTACTTCCTGCGGGGAATCCAAGAATGCTTGATTGGTTAAAACCCGATGATATGAAGCG
CATAGTAGATATGTTAAAAGAACAGTTCAATTTCGTTTTAATTGACTGCCCTGCAGGAGTTGAAGATGGATTTAAAAATG
CTATGGCAGCCTCTCAAGAAGCAATTGTAGTTACCAACCCTGAGGTATCAGCAGTAAGAGATGCAGACAGAGTAATTGGT
CTACTTAACACAAATTCCATTAAACCAGTCCAATTAGTTCTTAATCGAGTTAGGCCAAAGATGATGGCCAACCAAGAAAT
GCTTTCTATCGATGATGTGACTGATATTTTAGCCTTACCTTTACTTGGCCTTGTGCTAGAGGATGAACAAGTAATTGTAA
GTACAAACCGAGGTGAGCCACTAACTTTAAATAGCGTTAATTCCCCAGCAGCTAAATGTTATCTAAATATTGCAAAGAGA
TTACAAGGAGAAGATATTCCACTTATTGATCCAGCAGAGGAGATTTCTGGATTTGGTGCGAAATTTAGAAGACTAATGCA
AACAAAAATTTTCTAA

Upstream 100 bases:

>100_bases
TAAAGATGTCTTCAAAAGCAAACCCAATGCAAACGATCTAACAATAAAGCTTTTTTCTTCATCAAAATCGAACTAAAGTT
TGTCGAATCCAAGGAGGTCA

Downstream 100 bases:

>100_bases
AGCAATGGCAATGACACTTAGAGACATTATCAACAAGTTACTACGTAGACAGCCTGCTAGCGCTAGTACCGCGAGAGAGA
GGTTGCAACTTGTTCTAGCT

Product: putative septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MATDTRVILICSGKGGVGKTTLTANLGISLARQGLTTAVLDADFGLRNLDLLLGLENRIVYTAQEVLEEECRLDQALVKH
KQESNLSLLPAGNPRMLDWLKPDDMKRIVDMLKEQFNFVLIDCPAGVEDGFKNAMAASQEAIVVTNPEVSAVRDADRVIG
LLNTNSIKPVQLVLNRVRPKMMANQEMLSIDDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLNSVNSPAAKCYLNIAKR
LQGEDIPLIDPAEEISGFGAKFRRLMQTKIF

Sequences:

>Translated_271_residues
MATDTRVILICSGKGGVGKTTLTANLGISLARQGLTTAVLDADFGLRNLDLLLGLENRIVYTAQEVLEEECRLDQALVKH
KQESNLSLLPAGNPRMLDWLKPDDMKRIVDMLKEQFNFVLIDCPAGVEDGFKNAMAASQEAIVVTNPEVSAVRDADRVIG
LLNTNSIKPVQLVLNRVRPKMMANQEMLSIDDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLNSVNSPAAKCYLNIAKR
LQGEDIPLIDPAEEISGFGAKFRRLMQTKIF
>Mature_270_residues
ATDTRVILICSGKGGVGKTTLTANLGISLARQGLTTAVLDADFGLRNLDLLLGLENRIVYTAQEVLEEECRLDQALVKHK
QESNLSLLPAGNPRMLDWLKPDDMKRIVDMLKEQFNFVLIDCPAGVEDGFKNAMAASQEAIVVTNPEVSAVRDADRVIGL
LNTNSIKPVQLVLNRVRPKMMANQEMLSIDDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLNSVNSPAAKCYLNIAKRL
QGEDIPLIDPAEEISGFGAKFRRLMQTKIF

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=256, Percent_Identity=24.21875, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI118572611, Length=270, Percent_Identity=24.8148148148148, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787423, Length=262, Percent_Identity=42.3664122137405, Blast_Score=206, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322188, Length=278, Percent_Identity=24.1007194244604, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29723; Mature: 29592

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDTRVILICSGKGGVGKTTLTANLGISLARQGLTTAVLDADFGLRNLDLLLGLENRIV
CCCCCEEEEEECCCCCCCCEEEEECCCHHHHHCCCCEEEEECCCCCCCCCEEEECCCCEE
YTAQEVLEEECRLDQALVKHKQESNLSLLPAGNPRMLDWLKPDDMKRIVDMLKEQFNFVL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCEEE
IDCPAGVEDGFKNAMAASQEAIVVTNPEVSAVRDADRVIGLLNTNSIKPVQLVLNRVRPK
EECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHCHH
MMANQEMLSIDDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLNSVNSPAAKCYLNIAKR
HHCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
LQGEDIPLIDPAEEISGFGAKFRRLMQTKIF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATDTRVILICSGKGGVGKTTLTANLGISLARQGLTTAVLDADFGLRNLDLLLGLENRIV
CCCCEEEEEECCCCCCCCEEEEECCCHHHHHCCCCEEEEECCCCCCCCCEEEECCCCEE
YTAQEVLEEECRLDQALVKHKQESNLSLLPAGNPRMLDWLKPDDMKRIVDMLKEQFNFVL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCEEE
IDCPAGVEDGFKNAMAASQEAIVVTNPEVSAVRDADRVIGLLNTNSIKPVQLVLNRVRPK
EECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHEEEEECCCCCCHHHHHHHHHCHH
MMANQEMLSIDDVTDILALPLLGLVLEDEQVIVSTNRGEPLTLNSVNSPAAKCYLNIAKR
HHCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
LQGEDIPLIDPAEEISGFGAKFRRLMQTKIF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]